/*! tailwindcss v4.2.1 | MIT License | https://tailwindcss.com */
@layer properties{@supports (((-webkit-hyphens:none)) and (not (margin-trim:inline))) or ((-moz-orient:inline) and (not (color:rgb(from red r g b)))){*,:before,:after{--tw-rotate-x:initial;--tw-rotate-y:initial;--tw-rotate-z:initial;--tw-skew-x:initial;--tw-skew-y:initial;--tw-border-style:solid;--tw-ordinal:initial;--tw-slashed-zero:initial;--tw-numeric-figure:initial;--tw-numeric-spacing:initial;--tw-numeric-fraction:initial;--tw-shadow:0 0 #0000;--tw-shadow-color:initial;--tw-shadow-alpha:100%;--tw-inset-shadow:0 0 #0000;--tw-inset-shadow-color:initial;--tw-inset-shadow-alpha:100%;--tw-ring-color:initial;--tw-ring-shadow:0 0 #0000;--tw-inset-ring-color:initial;--tw-inset-ring-shadow:0 0 #0000;--tw-ring-inset:initial;--tw-ring-offset-width:0px;--tw-ring-offset-color:#fff;--tw-ring-offset-shadow:0 0 #0000;--tw-outline-style:solid;--tw-blur:initial;--tw-brightness:initial;--tw-contrast:initial;--tw-grayscale:initial;--tw-hue-rotate:initial;--tw-invert:initial;--tw-opacity:initial;--tw-saturate:initial;--tw-sepia:initial;--tw-drop-shadow:initial;--tw-drop-shadow-color:initial;--tw-drop-shadow-alpha:100%;--tw-drop-shadow-size:initial}::backdrop{--tw-rotate-x:initial;--tw-rotate-y:initial;--tw-rotate-z:initial;--tw-skew-x:initial;--tw-skew-y:initial;--tw-border-style:solid;--tw-ordinal:initial;--tw-slashed-zero:initial;--tw-numeric-figure:initial;--tw-numeric-spacing:initial;--tw-numeric-fraction:initial;--tw-shadow:0 0 #0000;--tw-shadow-color:initial;--tw-shadow-alpha:100%;--tw-inset-shadow:0 0 #0000;--tw-inset-shadow-color:initial;--tw-inset-shadow-alpha:100%;--tw-ring-color:initial;--tw-ring-shadow:0 0 #0000;--tw-inset-ring-color:initial;--tw-inset-ring-shadow:0 0 #0000;--tw-ring-inset:initial;--tw-ring-offset-width:0px;--tw-ring-offset-color:#fff;--tw-ring-offset-shadow:0 0 #0000;--tw-outline-style:solid;--tw-blur:initial;--tw-brightness:initial;--tw-contrast:initial;--tw-grayscale:initial;--tw-hue-rotate:initial;--tw-invert:initial;--tw-opacity:initial;--tw-saturate:initial;--tw-sepia:initial;--tw-drop-shadow:initial;--tw-drop-shadow-color:initial;--tw-drop-shadow-alpha:100%;--tw-drop-shadow-size:initial}}}@layer theme{:root,:host{--font-sans:ui-sans-serif, system-ui, sans-serif, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", "Noto Color Emoji";--font-mono:ui-monospace, SFMono-Regular, Menlo, Monaco, Consolas, "Liberation Mono", "Courier New", monospace;--spacing:.25rem;--default-transition-duration:.15s;--default-transition-timing-function:cubic-bezier(.4, 0, .2, 1);--default-font-family:var(--font-sans);--default-mono-font-family:var(--font-mono)}}@layer base{*,:after,:before{box-sizing:border-box;border:0 solid;margin:0;padding:0}::backdrop{box-sizing:border-box;border:0 solid;margin:0;padding:0}::file-selector-button{box-sizing:border-box;border:0 solid;margin:0;padding:0}html,:host{-webkit-text-size-adjust:100%;tab-size:4;line-height:1.5;font-family:var(--default-font-family,ui-sans-serif, system-ui, sans-serif, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", "Noto Color Emoji");font-feature-settings:var(--default-font-feature-settings,normal);font-variation-settings:var(--default-font-variation-settings,normal);-webkit-tap-highlight-color:transparent}hr{height:0;color:inherit;border-top-width:1px}abbr:where([title]){-webkit-text-decoration:underline dotted;text-decoration:underline dotted}h1,h2,h3,h4,h5,h6{font-size:inherit;font-weight:inherit}a{color:inherit;-webkit-text-decoration:inherit;-webkit-text-decoration:inherit;-webkit-text-decoration:inherit;-webkit-text-decoration:inherit;text-decoration:inherit}b,strong{font-weight:bolder}code,kbd,samp,pre{font-family:var(--default-mono-font-family,ui-monospace, SFMono-Regular, Menlo, Monaco, Consolas, "Liberation Mono", "Courier New", monospace);font-feature-settings:var(--default-mono-font-feature-settings,normal);font-variation-settings:var(--default-mono-font-variation-settings,normal);font-size:1em}small{font-size:80%}sub,sup{vertical-align:baseline;font-size:75%;line-height:0;position:relative}sub{bottom:-.25em}sup{top:-.5em}table{text-indent:0;border-color:inherit;border-collapse:collapse}:-moz-focusring{outline:auto}progress{vertical-align:baseline}summary{display:list-item}ol,ul,menu{list-style:none}img,svg,video,canvas,audio,iframe,embed,object{vertical-align:middle;display:block}img,video{max-width:100%;height:auto}button,input,select,optgroup,textarea{font:inherit;font-feature-settings:inherit;font-variation-settings:inherit;letter-spacing:inherit;color:inherit;opacity:1;background-color:#0000;border-radius:0}::file-selector-button{font:inherit;font-feature-settings:inherit;font-variation-settings:inherit;letter-spacing:inherit;color:inherit;opacity:1;background-color:#0000;border-radius:0}:where(select:is([multiple],[size])) optgroup{font-weight:bolder}:where(select:is([multiple],[size])) optgroup option{padding-inline-start:20px}::file-selector-button{margin-inline-end:4px}::placeholder{opacity:1}@supports (not ((-webkit-appearance:-apple-pay-button))) or (contain-intrinsic-size:1px){::placeholder{color:currentColor}@supports (color:color-mix(in lab, red, red)){::placeholder{color:color-mix(in oklab, currentcolor 50%, transparent)}}}textarea{resize:vertical}::-webkit-search-decoration{-webkit-appearance:none}::-webkit-date-and-time-value{min-height:1lh;text-align:inherit}::-webkit-datetime-edit{display:inline-flex}::-webkit-datetime-edit-fields-wrapper{padding:0}::-webkit-datetime-edit{padding-block:0}::-webkit-datetime-edit-year-field{padding-block:0}::-webkit-datetime-edit-month-field{padding-block:0}::-webkit-datetime-edit-day-field{padding-block:0}::-webkit-datetime-edit-hour-field{padding-block:0}::-webkit-datetime-edit-minute-field{padding-block:0}::-webkit-datetime-edit-second-field{padding-block:0}::-webkit-datetime-edit-millisecond-field{padding-block:0}::-webkit-datetime-edit-meridiem-field{padding-block:0}::-webkit-calendar-picker-indicator{line-height:1}:-moz-ui-invalid{box-shadow:none}button,input:where([type=button],[type=reset],[type=submit]){-webkit-appearance:button;appearance:button}::file-selector-button{-webkit-appearance:button;appearance:button}::-webkit-inner-spin-button{height:auto}::-webkit-outer-spin-button{height:auto}[hidden]:where(:not([hidden=until-found])){display:none!important}}@layer components;@layer utilities{.collapse{visibility:collapse}.invisible{visibility:hidden}.visible{visibility:visible}.absolute{position:absolute}.fixed{position:fixed}.relative{position:relative}.static{position:static}.sticky{position:sticky}.start{inset-inline-start:var(--spacing)}.end{inset-inline-end:var(--spacing)}.top-100{top:calc(var(--spacing) * 100)}.container{width:100%}@media (min-width:40rem){.container{max-width:40rem}}@media (min-width:48rem){.container{max-width:48rem}}@media (min-width:64rem){.container{max-width:64rem}}@media (min-width:80rem){.container{max-width:80rem}}@media (min-width:96rem){.container{max-width:96rem}}.block{display:block}.contents{display:contents}.flex{display:flex}.grid{display:grid}.hidden{display:none}.inline{display:inline}.table{display:table}.shrink{flex-shrink:1}.grow{flex-grow:1}.transform{transform:var(--tw-rotate-x,) var(--tw-rotate-y,) var(--tw-rotate-z,) var(--tw-skew-x,) var(--tw-skew-y,)}.resize{resize:both}.rounded{border-radius:.25rem}.border{border-style:var(--tw-border-style);border-width:1px}.lowercase{text-transform:lowercase}.uppercase{text-transform:uppercase}.italic{font-style:italic}.ordinal{--tw-ordinal:ordinal;font-variant-numeric:var(--tw-ordinal,) var(--tw-slashed-zero,) var(--tw-numeric-figure,) var(--tw-numeric-spacing,) var(--tw-numeric-fraction,)}.shadow{--tw-shadow:0 1px 3px 0 var(--tw-shadow-color,#0000001a), 0 1px 2px -1px var(--tw-shadow-color,#0000001a);box-shadow:var(--tw-inset-shadow), var(--tw-inset-ring-shadow), var(--tw-ring-offset-shadow), var(--tw-ring-shadow), var(--tw-shadow)}.ring{--tw-ring-shadow:var(--tw-ring-inset,) 0 0 0 calc(1px + var(--tw-ring-offset-width)) var(--tw-ring-color,currentcolor);box-shadow:var(--tw-inset-shadow), var(--tw-inset-ring-shadow), var(--tw-ring-offset-shadow), var(--tw-ring-shadow), var(--tw-shadow)}.outline{outline-style:var(--tw-outline-style);outline-width:1px}.blur{--tw-blur:blur(8px);filter:var(--tw-blur,) var(--tw-brightness,) var(--tw-contrast,) var(--tw-grayscale,) var(--tw-hue-rotate,) var(--tw-invert,) var(--tw-saturate,) var(--tw-sepia,) var(--tw-drop-shadow,)}.grayscale{--tw-grayscale:grayscale(100%);filter:var(--tw-blur,) var(--tw-brightness,) var(--tw-contrast,) var(--tw-grayscale,) var(--tw-hue-rotate,) var(--tw-invert,) var(--tw-saturate,) var(--tw-sepia,) var(--tw-drop-shadow,)}.invert{--tw-invert:invert(100%);filter:var(--tw-blur,) var(--tw-brightness,) var(--tw-contrast,) var(--tw-grayscale,) var(--tw-hue-rotate,) var(--tw-invert,) var(--tw-saturate,) var(--tw-sepia,) var(--tw-drop-shadow,)}.filter{filter:var(--tw-blur,) var(--tw-brightness,) var(--tw-contrast,) var(--tw-grayscale,) var(--tw-hue-rotate,) var(--tw-invert,) var(--tw-saturate,) var(--tw-sepia,) var(--tw-drop-shadow,)}.transition{transition-property:color,background-color,border-color,outline-color,text-decoration-color,fill,stroke,--tw-gradient-from,--tw-gradient-via,--tw-gradient-to,opacity,box-shadow,transform,translate,scale,rotate,filter,-webkit-backdrop-filter,backdrop-filter,display,content-visibility,overlay,pointer-events;transition-timing-function:var(--tw-ease,var(--default-transition-timing-function));transition-duration:var(--tw-duration,var(--default-transition-duration))}}:root{--ink:#1f4e79;--muted:#666;--paper:#fff;--cyan:#35cbf5;--red:#ff2d16;--line:#f5f5f5;--serif:Georgia, "Songti SC", "STSong", serif;--sans:"Helvetica Neue", Arial, "PingFang SC", "Microsoft YaHei", sans-serif}*{box-sizing:border-box}html{scroll-behavior:smooth;scroll-padding-top:110px}body{background:var(--paper);color:var(--ink);font-family:var(--sans);-webkit-font-smoothing:antialiased;margin:0}a{color:inherit;text-decoration:none}button,input,select{font:inherit}:is(a:focus-visible,button:focus-visible){outline:3px solid var(--red);outline-offset:6px}p{line-height:1.85}h1,h2,h3,p{margin-top:0}.skip{z-index:100;background:#fff;padding:15px;position:fixed;top:-100px;left:20px}.skip:focus{top:10px}.site-header{border-bottom:1px solid var(--line);justify-content:space-between;align-items:center;gap:30px;min-height:110px;margin:0 4.5%;display:flex}.logo{width:125px;height:auto}.site-header nav{align-items:center;gap:38px;font-size:14px;display:flex}.site-header nav a:hover,.text-link:hover{color:#014694}.hero{grid-template-columns:1.1fr 1fr;gap:5%;padding:72px 4.5% 64px;display:grid}.eyebrow{letter-spacing:.14em;text-transform:uppercase;margin-bottom:32px;font-size:12px;font-weight:600}.hero h1{letter-spacing:-.04em;margin-bottom:30px;font-size:clamp(40px,4.2vw,67px);line-height:1.32}.hero h1 span{color:#666}.hero-deck{max-width:430px;margin-bottom:36px;font-size:17px;line-height:1.9}.text-link{border-bottom:1px solid var(--ink);justify-content:space-between;gap:45px;padding:10px 0;font-size:14px;display:inline-flex}.hero-evidence{padding-top:7px}.hero-evidence .eyebrow{margin-bottom:24px}.facility-window{aspect-ratio:1.15;background-color:#f5f5f5;background-image:url(/assets/platform-source.png);background-position:95% 75%;background-repeat:no-repeat;background-size:238%;width:100%}.image-caption{letter-spacing:.08em;justify-content:space-between;padding-top:14px;font-size:11px;display:flex}.image-caption span{color:var(--muted)}.company-strip{border-top:1px solid var(--line);border-bottom:1px solid var(--line);grid-template-columns:1fr 2fr .7fr;align-items:baseline;gap:4%;margin:0 4.5%;padding:30px 0;display:grid}.company-strip p{margin:0}.company-strip p:nth-child(2){font-size:19px;line-height:1.7}.company-strip a{text-align:right;font-size:13px}.section{padding:85px 4.5%}.section-heading{grid-template-columns:1fr 2.8fr;gap:4%;margin-bottom:36px;display:grid}.section h2{letter-spacing:-.025em;font-size:36px;line-height:1.4}.program-preview{background:#f5f5f5;grid-template-columns:1fr 1.6fr;gap:8%;padding:42px;display:grid}.small-label{letter-spacing:.035em;font-size:12px}.program-preview h3{margin:20px 0;font-size:30px}.program-preview p{font-size:14px}.status-rows>div{border-bottom:1px solid #d3d3d3;justify-content:space-between;gap:20px;padding:16px 0;font-size:14px;display:flex}.status-rows strong{font-weight:500}.status-rows span{color:#666}.source-note{margin:20px 0 0;font-size:11px!important}.source-note a{text-underline-offset:4px;text-decoration:underline}.investor-preview{background:#f5f5f5}.document-row{border-top:1px solid #d3d3d3;border-bottom:1px solid #d3d3d3;grid-template-columns:1fr 2fr 1fr;align-items:center;gap:30px;padding:28px 0;display:grid}.document-row time{font-size:13px}.document-row h3{margin:0;font-size:20px}.document-row>span{text-align:right;font-size:12px}.site-footer{grid-template-columns:1fr 1fr;gap:24px;padding:55px 4.5%;display:grid}.site-footer p{margin:0}.site-footer>a{text-underline-offset:6px;font-size:14px;text-decoration:underline}.site-footer .small-label{color:var(--muted)}@media (max-width:760px){.site-header{min-height:90px}.logo{width:100px}.site-header nav{gap:16px;font-size:12px}.site-header nav a:nth-child(-n+2){display:none}.hero{grid-template-columns:1fr;gap:44px;padding-top:42px}.hero h1{font-size:42px}.hero-deck{font-size:16px}.hero-evidence{max-width:550px}.company-strip{grid-template-columns:1fr;gap:18px;padding:25px 0}.company-strip a{text-align:left}.company-strip p:nth-child(2){font-size:17px}.section{padding-top:50px;padding-bottom:50px}.section-heading{grid-template-columns:1fr;gap:0}.section-heading .eyebrow{margin-bottom:20px}.section h2{font-size:30px}.program-preview{grid-template-columns:1fr;gap:15px;padding:25px 20px}.status-rows>div{gap:10px;font-size:12px}.document-row{grid-template-columns:1fr;gap:12px}.document-row>span{text-align:left}.site-footer{grid-template-columns:1fr}.eyebrow{margin-bottom:24px}}@media (prefers-reduced-motion:reduce){html{scroll-behavior:auto}}.site{--ink:#1f4e79;--paper:#fff;--line:#d3d3d3;color:var(--ink);background:var(--paper)}.site h1,.site h2{font-family:var(--serif);letter-spacing:-.035em;font-weight:400}.site h1{font-size:clamp(42px,5vw,74px);line-height:1.16}.site h2{font-size:39px;line-height:1.3}.site h3{letter-spacing:-.015em;font-size:23px;line-height:1.45}.site p{font-size:16px}.site .eyebrow{font-family:var(--sans);letter-spacing:.1em;font-size:12px;font-weight:650;line-height:1.5}.site .source-note{color:#666;line-height:1.75;font-size:12px!important}.site .small-label{font-size:12px}.site-header .brand{flex-shrink:0}.site .site-header{height:110px;margin:0 4.5%}.site .site-header .logo{object-fit:contain}.site .desktop-nav a{white-space:nowrap;font-size:13px;position:relative}.desktop-nav a[aria-current=page]:after{content:"";background:var(--red);height:2px;position:absolute;bottom:-18px;left:0;right:0}.header-actions{align-items:center;gap:20px;font-size:13px;display:flex}.locale-link{border-left:1px solid var(--line);padding:10px}.menu-toggle{color:inherit;background:0 0;border:0;padding:10px 0;display:none}.mobile-navigation{display:none}.red-rule{align-items:center;gap:15px;display:flex}.red-rule:before{content:"";background:var(--red);flex-shrink:0;width:26px;height:3px;display:inline-block}.home-hero{padding:62px 4.5% 44px}.hero-title h1{max-width:1180px;margin:40px 0 48px}.home-hero-bottom{grid-template-columns:1.35fr 1fr;align-items:start;gap:8%;display:grid}.home-hero figure{margin:0}.documentary-photo{aspect-ratio:1.85;background:#f5f5f5 url(/assets/platform-source.png) 94% 71%/245% no-repeat;width:100%}.site figcaption{letter-spacing:.025em;color:#666;margin-top:11px;font-size:11px;line-height:1.7}.hero-intro{padding-top:0}.hero-intro>p:first-child{margin-bottom:35px;font-size:17px;line-height:1.85}.hero-intro .text-link{width:100%;margin:0 0 15px}.milestone-band{color:#fff;background:#1f4e79;grid-template-columns:1.3fr 1fr 1fr 1fr .75fr;align-items:baseline;gap:28px;padding:33px 4.5%;display:grid}.milestone-band>.eyebrow{color:#35cbf5;max-width:150px;margin:0}.milestone-band>div{border-left:1px solid #666;padding-left:23px}.milestone-band>div>span{font-family:var(--serif);font-size:27px;line-height:1}.milestone-band p{margin:10px 0 0;font-size:12px;line-height:1.5}.milestone-band>a{white-space:nowrap;font-size:12px}.site .section{padding:76px 4.5%}.split-heading{justify-content:space-between;align-items:end;gap:35px;margin-bottom:34px;display:flex}.split-heading h2{max-width:750px;margin:0}.split-heading .eyebrow{margin-bottom:19px}.split-heading>.text-link{white-space:nowrap;flex-shrink:0}.program-overview{border-top:3px solid var(--cyan);border-bottom:1px solid var(--line);grid-template-columns:1fr 1.6fr;gap:6%;padding:35px 0;display:grid}.program-overview>div:first-child{border-right:1px solid var(--line);padding-right:35px}.program-overview h3{margin:20px 0}.program-overview p{font-size:14px}.site .status-rows>div{align-items:start;gap:20px;padding:17px 0;font-size:14px}.status-rows>div>strong{flex-shrink:0;width:44%}.status-rows>div>span{text-align:right}.site .home-investors{background:#f5f5f5;grid-template-columns:1fr 1.6fr;gap:8%;display:grid}.home-investors>div>p:not(.eyebrow){font-size:13px}.site .home-investors .document-row{grid-template-columns:1fr;align-content:center;align-self:center;gap:14px;padding:26px 0}.home-investors .document-row h3{font-size:24px}.home-investors .document-row p{margin:0;font-size:14px}.home-investors .document-row>span{text-align:left;color:#014694}.journal-links{grid-template-columns:1fr 1fr;gap:8%;display:grid}.journal-links>a{border-top:1px solid var(--line);padding:25px 0}.journal-links time{color:var(--muted);font-size:13px}.journal-links h3{max-width:510px;margin:23px 0 35px;font-size:26px;line-height:1.45}.journal-links>a>span{font-size:13px}.page-heading{border-bottom:1px solid var(--line);padding:62px 4.5% 55px}.page-heading h1{max-width:1160px;margin:32px 0 30px}.page-heading>p:not(.eyebrow){max-width:700px;font-size:17px}.page-heading .eyebrow{margin-bottom:0}.page-heading .text-link{margin-top:15px}.footer{color:#fff;background:#1f4e79;padding:60px 4.5% 25px}.footer-top{grid-template-columns:1fr 1fr 1.2fr;gap:8%;padding-bottom:42px;display:grid}.footer-top>div:first-child>p{max-width:220px;margin:24px 0 12px;font-size:14px}.footer-nav{grid-template-columns:1fr 1fr;align-content:start;gap:16px 20px;font-size:13px;display:grid}.footer-contact .eyebrow{color:#d3d3d3;margin-bottom:25px}.footer-contact>a{overflow-wrap:anywhere;border-bottom:1px solid #d3d3d3;padding-bottom:8px;font-size:16px}.footer-contact p:not(.eyebrow){color:#f5f5f5;margin-top:24px;font-size:13px;line-height:1.8}.safety-strip{border-top:1px solid #666;border-bottom:1px solid #666;justify-content:space-between;align-items:center;gap:28px;padding:26px 0;display:flex}.safety-strip>div{align-items:center;gap:26px;display:flex}.safety-strip strong{color:#f5f5f5;font-size:12px;font-weight:400}.safety-strip>div>a{white-space:nowrap;font-size:19px}.safety-strip>a{overflow-wrap:anywhere;font-size:13px}.footer-bottom{color:#d3d3d3;justify-content:space-between;gap:25px;margin-top:25px;font-size:11px;display:flex}.site a:hover{color:#014694}.footer a:hover{color:#35cbf5}.page-heading+.section{padding-top:55px}.science-intro{grid-template-columns:1.2fr 1fr;gap:10%;display:grid}.science-intro h2{font-size:36px}.science-definition{border-top:3px solid var(--cyan);background:#f5f5f5;padding:35px 35px 20px}.science-definition>div+div{border-top:1px solid #d3d3d3;margin-top:25px;padding-top:25px}.science-definition span{font-family:var(--serif);font-size:31px}.science-definition h3{margin:10px 0;font-size:16px}.science-definition p{font-size:14px}.science-definition>p{color:var(--muted);margin:30px 0 0}.pipeline-section{background:#f5f5f5}.pipeline-intro{grid-template-columns:1.5fr 1fr;gap:8%;margin-bottom:28px;display:grid}.filter-tabs{border-bottom:1px solid var(--line);flex-wrap:wrap;gap:3px;padding-bottom:0;display:flex}.filter-tabs button{color:var(--ink);cursor:pointer;background:0 0;border:0;border-bottom:3px solid #0000;padding:14px 20px;font-size:13px}.filter-tabs button[aria-pressed=true]{border-bottom-color:var(--cyan);font-weight:600}.results-count{color:var(--muted);margin:18px 0;font-size:12px!important}.pipeline-labels,.pipeline-row{grid-template-columns:1fr 1fr 1.55fr;gap:4%;display:grid}.pipeline-labels{color:var(--muted);border-bottom:1px solid #d3d3d3;padding:14px 0;font-size:12px}.pipeline-row{border-bottom:1px solid #d3d3d3;align-items:start;padding:30px 0}.pipeline-row h3{margin:0 0 8px;font-size:20px}.pipeline-row p{margin:8px 0;font-size:13px;line-height:1.8}.status-badge{border:1px solid #d3d3d3;margin-bottom:6px;padding:5px 9px;font-size:11px;line-height:1.4;display:inline-block}.marketed .status-badge{color:#fff;background:#1f4e79;border-color:#1f4e79}.pipeline-row .source-note{text-underline-offset:4px;text-decoration:underline;font-size:11px!important}.process-list{grid-template-columns:repeat(7,1fr);margin:40px 0;padding:0;list-style:none;display:grid}.process-list li{border-top:1px solid var(--line);border-right:1px solid var(--line);padding:20px 18px;font-size:13px;line-height:1.65}.process-list li:first-child{padding-left:0}.process-list li:last-child{border-right:0}.process-list span{color:#666;margin-bottom:12px;font-size:11px;display:block}.platform-detail{grid-template-columns:1.3fr 1fr;align-items:start;gap:7%;display:grid}.platform-detail figure{margin:0}.platform-detail img{max-width:100%;display:block}.platform-detail p{font-size:14px}.publications{background:#f5f5f5}.publication-row{border-top:1px solid #d3d3d3;grid-template-columns:.25fr 2fr .1fr;gap:35px;padding:28px 0;display:grid}.publication-row time{font-size:13px}.publication-row h3{margin-bottom:12px;font-size:22px}.publication-row p{margin-bottom:0;font-size:13px}.company-intro{grid-template-columns:1fr 1.4fr;gap:10%;display:grid}.company-intro h2{font-size:33px}.mission-section{background:#f5f5f5;grid-template-columns:1fr 1fr;gap:8%;display:grid}.mission-section h2{font-size:32px}.mission-section p{font-size:15px}.history-grid{grid-template-columns:.7fr 1.5fr;align-items:start;gap:12%;display:grid}.history-grid figure{margin:0;position:sticky;top:40px}.history-grid img{width:100%;max-width:280px;display:block}.history-row{border-top:1px solid var(--line);grid-template-columns:.28fr 1fr;gap:40px;padding:24px 0;display:grid}.history-row time{font-family:var(--serif);font-size:29px}.history-row p{margin:0;font-size:14px;line-height:1.9}.leadership-section{background:#f5f5f5}.people-grid{grid-template-columns:repeat(4,1fr);gap:35px;margin-top:42px;display:grid}.people-grid img{aspect-ratio:1;object-fit:cover;object-position:top;filter:grayscale();background:#fff;width:100%}.people-grid h3{margin:22px 0 10px;font-size:21px}.people-grid p{font-size:13px;line-height:1.7}.people-grid span{font-size:12px}.company-links{gap:60px;display:flex}.company-links a{border-top:1px solid var(--line);font-size:20px;font-family:var(--serif);flex:1;justify-content:space-between;gap:30px;padding-top:23px;display:flex}.institution-grid{grid-template-columns:repeat(3,1fr);gap:30px;display:grid}.institution-grid>a{border-top:1px solid var(--line);flex-direction:column;justify-content:space-between;gap:35px;padding:22px 0;display:flex}.institution-grid h2{font-size:26px}.institution-grid span{font-size:12px}.source-institutions{max-width:100%;margin:auto;display:block}.archive-controls{align-items:end;gap:25px;padding-bottom:20px;display:flex}.archive-controls label{flex-direction:column;gap:10px;font-size:12px;display:flex}.archive-controls input,.archive-controls select{min-height:43px;color:var(--ink);background:0 0;border:1px solid #d3d3d3;border-radius:0;padding:11px 12px}.archive-controls input{width:280px}.archive-controls select{min-width:115px}.archive-controls>span{align-self:center;margin-left:auto;font-size:12px}.plain-button{border:0;border-bottom:1px solid var(--line);color:var(--ink);cursor:pointer;background:0 0;padding:12px 0;font-size:12px}.news-row{border-top:1px solid var(--line);grid-template-columns:.4fr 2fr .1fr;align-items:baseline;gap:8%;padding:31px 0;display:grid}.news-row time{color:var(--muted);font-size:13px}.site .news-row h2,.site .news-row h3{font-family:var(--sans);letter-spacing:-.015em;margin:0;font-size:23px;font-weight:400;line-height:1.6}.news-row>span{text-align:right;font-size:20px}.pagination{flex-wrap:wrap;justify-content:center;gap:6px;margin:35px 0 0;display:flex}.pagination button{border:1px solid var(--line);min-width:40px;min-height:40px;color:var(--ink);cursor:pointer;background:0 0;padding:10px 13px;font-size:13px}.pagination button[aria-current=page]{background:var(--ink);border-color:var(--ink);color:#fff}.pagination button:disabled{opacity:.35;cursor:default}.empty-state{border-top:1px solid var(--line);padding:60px 0}.detail-page{padding:45px 4.5% 70px}.detail-heading{max-width:980px;margin:0 0 50px 18%}.back-link{margin-bottom:55px;font-size:13px;display:inline-block}.article-meta{color:var(--muted);gap:25px;margin-bottom:22px;font-size:12px;display:flex}.site .detail-heading h1{letter-spacing:-.02em;margin-bottom:23px;font-size:clamp(32px,3.3vw,49px);line-height:1.35}.detail-subtitle{line-height:1.5;font-size:19px!important}.article-layout{grid-template-columns:.55fr 2fr;gap:6%;max-width:1100px;margin:auto;display:grid}.article-aside{border-top:1px solid var(--line);padding-top:20px;font-size:12px}.article-aside p{color:var(--muted);margin:0 0 17px;font-size:12px;line-height:1.75}.article-aside>a{text-underline-offset:4px;margin-bottom:22px;font-size:12px;text-decoration:underline;display:inline-block}.article-body{overflow-wrap:anywhere;min-width:0}.article-body p{margin:0 0 24px;font-size:17px;line-height:1.95}.article-body h3{margin:36px 0 20px;font-size:25px;font-weight:500}.article-body ul,.article-body ol{margin:24px 0;padding-left:1.5em}.article-body li{margin:0 0 12px;font-size:16px;line-height:1.9}.article-body li p{margin:0 0 10px}.article-body a{text-underline-offset:4px;color:#014694;text-decoration:underline}.article-body figure{margin:32px 0}.article-body figure img{max-width:100%;height:auto;margin:0 auto;display:block}.article-body video{width:100%}.article-body strong{font-weight:600}.article-body .table-scroll{border:1px solid var(--line);margin:30px 0;overflow:auto}.article-body table{border-collapse:collapse;width:100%;min-width:500px}.article-body td,.article-body th{border:1px solid var(--line);text-align:left;padding:12px}.article-body td p,.article-body th p{margin:0;font-size:13px}.context-note{border-left:3px solid var(--cyan);background:#f5f5f5;margin-bottom:35px;padding:20px 25px}.article-body .context-note p{margin:0 0 12px;font-size:13px;line-height:1.9}.context-note a{font-size:12px}.context-note strong{margin-bottom:12px;font-size:14px;display:block}.article-end{border-top:1px solid var(--line);margin-top:45px;padding:25px 0;font-size:14px}.detail-bottom{padding:0 4.5% 60px}.investor-layout{grid-template-columns:.65fr 2.1fr;gap:7%;padding:50px 4.5% 75px;display:grid}.investor-nav{flex-direction:column;align-self:start;display:flex;position:sticky;top:25px}.investor-nav a{border-top:1px solid var(--line);justify-content:space-between;gap:15px;padding:18px 0;font-size:14px;display:flex}.investor-nav a[aria-current=page]{color:#014694;border-top:2px solid var(--cyan);font-weight:600}.investor-nav span{font-size:12px}.investor-content{min-width:0}.investor-content>h2{margin:35px 0 25px;font-size:31px}.investor-content>h2:first-child{margin-top:0}.filing-row{border-top:1px solid var(--line);grid-template-columns:.32fr 1fr;gap:35px;padding:24px 0;display:grid}.filing-row time{font-size:12px;line-height:1.6;display:block}.filing-row .small-label{color:var(--muted);margin-top:8px;line-height:1.65;display:block}.filing-title{font-size:17px;line-height:1.65;display:block}.document-editions{color:#014694;flex-wrap:wrap;gap:24px;margin-top:14px;font-size:11px;display:flex}.board-list>div{border-top:1px solid var(--line);justify-content:space-between;gap:22px;padding:14px 0;display:flex}.board-list strong{font-size:14px;font-weight:500}.board-list span{color:var(--muted);font-size:12px}.committee-grid{grid-template-columns:1fr 1fr;gap:25px 40px;margin-bottom:45px;display:grid}.committee-grid h3{font-size:19px}.committee-grid ul{padding:0;list-style:none}.committee-grid li{font-size:13px;line-height:1.9}.archive-disclosure{border-top:1px solid var(--line);border-bottom:1px solid var(--line);margin:35px 0;padding:20px 0}.archive-disclosure summary{cursor:pointer;font-size:15px}.archive-disclosure>p{margin:20px 0;font-size:13px}.archive-disclosure .article-body{background:#f5f5f5;margin:30px 0;padding:25px}.contact-note{border-top:1px solid var(--line);margin-top:40px;padding-top:30px}.contact-grid{grid-template-columns:1fr 1fr;gap:10%;display:grid}.contact-grid>div{min-width:0}.contact-grid .eyebrow{margin-bottom:28px;display:block}.contact-grid h2{margin-bottom:30px;font-size:32px}.contact-big{font-family:var(--serif);overflow-wrap:anywhere;margin:25px 0;font-size:28px;display:block}.safety-email{overflow-wrap:anywhere;text-underline-offset:4px;font-size:14px;text-decoration:underline}.team-gallery{grid-template-columns:1fr 1fr;gap:35px;display:grid}.team-gallery figure{margin:0}.team-gallery img{width:100%;height:auto}.team-gallery ul{padding:0;list-style:none}.team-gallery li{margin-bottom:25px}.people-life{background:#f5f5f5}@media (max-width:1100px){.site .desktop-nav{gap:16px}.site .desktop-nav a{font-size:12px}.site .logo{width:110px}.milestone-band{grid-template-columns:1fr 1fr 1fr}.milestone-band>.eyebrow{grid-column:1/-1;max-width:none}.milestone-band>a{grid-column:1/-1}.footer-top{gap:35px}.safety-strip>div{flex-direction:column;align-items:start;gap:10px}.safety-strip{align-items:start}.archive-controls{flex-wrap:wrap}.archive-controls input{width:240px}}@media (max-width:820px){.site .desktop-nav{display:none}.site .site-header{height:88px;min-height:88px}.site .menu-toggle{align-items:center;gap:15px;display:flex}.mobile-navigation{border-bottom:1px solid var(--line);background:#f5f5f5;padding:15px 4.5% 30px;display:block}.mobile-navigation>a{border-bottom:1px solid #d3d3d3;align-items:center;gap:24px;padding:18px 0;font-size:20px;display:flex}.mobile-navigation>a>span:first-child{color:var(--muted);font-size:11px}.mobile-navigation>a>span:last-child{margin-left:auto}.mobile-navigation>div{gap:40px;margin-top:25px;font-size:13px;display:flex}.home-hero{padding-top:40px}.site h1{font-size:clamp(39px,6.8vw,58px)}.hero-title h1{margin:25px 0 35px}.home-hero-bottom{grid-template-columns:1fr;gap:30px}.home-hero figure{max-width:580px}.hero-intro>p:first-child{margin-bottom:23px;font-size:16px}.hero-intro .text-link{width:auto;min-width:260px}.home-hero{padding-bottom:32px}.milestone-band{gap:20px;padding-top:28px;padding-bottom:28px}.milestone-band>div{padding-left:15px}.milestone-band>div>span{font-size:23px}.milestone-band p{font-size:11px}.site .section{padding:50px 4.5%}.site h2{font-size:32px}.split-heading{flex-direction:column;align-items:start;gap:20px}.program-overview{grid-template-columns:1fr;gap:20px}.program-overview>div:first-child{border:0;padding-right:0}.site .home-investors{grid-template-columns:1fr;gap:32px}.home-investors>div .eyebrow{margin-bottom:16px}.site .home-investors .document-row{padding-top:25px}.journal-links{gap:30px}.journal-links h3{font-size:21px}.page-heading{padding:40px 4.5%}.page-heading>p:not(.eyebrow){font-size:16px}.footer{padding-top:40px}.footer-top{grid-template-columns:1fr 1fr;gap:35px}.footer-contact{grid-column:1/-1}.footer-contact p:not(.eyebrow){margin-bottom:0}.safety-strip{flex-direction:column;gap:20px}.safety-strip>div{flex-direction:row;align-items:center;gap:20px}.safety-strip>a{font-size:12px}.science-intro{grid-template-columns:1fr;gap:30px}.pipeline-intro{grid-template-columns:1fr;gap:0}.pipeline-labels{display:none}.pipeline-row{grid-template-columns:1fr 1.5fr;gap:18px 20px;padding:25px 0}.pipeline-row>div:last-child{border-top:1px dotted #d3d3d3;grid-column:1/-1;padding-top:17px}.pipeline-row h3{font-size:20px}.pipeline-row h4{font-size:14px}.filter-tabs button{padding:12px 13px;font-size:12px}.process-list{grid-template-columns:repeat(3,1fr);row-gap:25px}.process-list li:nth-child(4){padding-left:0}.platform-detail{grid-template-columns:1fr;gap:30px}.publication-row{grid-template-columns:.2fr 2fr .1fr;gap:20px}.publication-row h3{font-size:19px}.company-intro{grid-template-columns:1fr;gap:20px}.mission-section{grid-template-columns:1fr;gap:35px}.mission-section h2{font-size:28px}.history-grid{grid-template-columns:1fr;gap:35px}.history-grid figure{max-width:230px;position:static}.history-grid img{object-fit:contain;max-height:230px}.history-row{grid-template-columns:.25fr 1fr;gap:25px}.history-row time{font-size:26px}.people-grid{grid-template-columns:1fr 1fr;gap:35px 25px}.people-grid h3{font-size:20px}.company-links{flex-wrap:wrap;gap:30px}.company-links>a{min-width:160px}.institution-grid{grid-template-columns:1fr 1fr;gap:30px}.institution-grid h2{font-size:23px}.archive-controls{gap:15px}.archive-controls input{width:210px}.archive-controls label{font-size:11px}.archive-controls>span{margin-left:0}.news-row{grid-template-columns:1fr .1fr;gap:14px 18px;padding:24px 0}.news-row time{grid-column:1/-1;font-size:12px}.site .news-row h2,.site .news-row h3{font-size:21px;line-height:1.55}.pagination{gap:4px}.pagination button{min-width:36px;padding:8px 10px;font-size:12px}.detail-page{padding-top:30px}.detail-heading{margin-bottom:30px;margin-left:0}.back-link{margin-bottom:30px}.site .detail-heading h1{font-size:33px}.article-layout{grid-template-columns:1fr;gap:25px}.article-aside{flex-wrap:wrap;align-items:baseline;gap:10px 22px;padding-top:18px;display:flex}.article-aside p,.article-aside>a{margin:0}.article-aside>p:nth-last-child(-n+2){flex-basis:100%}.article-body p{font-size:16px;line-height:1.9}.article-body h3{font-size:23px}.article-body .context-note{padding:18px}.detail-bottom{padding-bottom:40px}.investor-layout{grid-template-columns:1fr;gap:30px;padding-top:25px}.investor-nav{grid-template-columns:1fr 1fr;gap:0 25px;display:grid;position:static}.investor-nav a{padding:13px 0;font-size:12px}.filing-row{grid-template-columns:1fr;gap:10px}.filing-title{font-size:16px;line-height:1.65}.document-editions{gap:20px;font-size:11px}.committee-grid{gap:20px}.committee-grid h3{font-size:17px}.board-list strong{font-size:13px}.board-list span{font-size:11px}.contact-grid{grid-template-columns:1fr;gap:50px}.contact-big{font-size:27px}.team-gallery{grid-template-columns:1fr}.contact-grid h2{font-size:29px}}@media (max-width:450px){.site h1{font-size:38px;line-height:1.24}.site[lang=zh-CN] .hero-title h1{letter-spacing:-.035em;font-size:34px}.milestone-band{grid-template-columns:1fr 1fr;gap:23px}.milestone-band>div:last-of-type{grid-column:1/-1}.milestone-band p{font-size:12px}.journal-links{grid-template-columns:1fr;gap:10px}.footer-top{grid-template-columns:1fr}.footer-nav{grid-column:1/-1;gap:17px}.footer-bottom{flex-wrap:wrap;gap:15px;font-size:10px}.safety-strip>div{flex-direction:column;align-items:start;gap:10px}.safety-strip>a{font-size:11px}.archive-controls input{width:190px}.archive-controls select{min-width:100px}.institution-grid,.committee-grid{grid-template-columns:1fr}.process-list{grid-template-columns:repeat(2,1fr)}.process-list li:nth-child(odd){padding-left:0}.process-list li:nth-child(2n){padding-left:18px}.contact-big{font-size:23px}}.primary-button{color:#fff;cursor:pointer;background:#1f4e79;border:1px solid #1f4e79;padding:15px 22px;font-size:14px;line-height:1.5}.professional-dialog{color:var(--ink);background:var(--paper);border:0;width:calc(100% - 36px);max-width:580px;max-height:calc(100dvh - 36px);margin:auto;padding:40px;overflow-y:auto;box-shadow:0 15px 80px #1f4e7960}.professional-dialog::backdrop{-webkit-backdrop-filter:blur(4px);backdrop-filter:blur(4px);background:#1f4e79b8}.professional-dialog h2{font-size:30px}.professional-dialog p{font-size:15px}.dialog-actions{flex-direction:column;gap:15px;margin-top:25px;display:flex}.dialog-actions .plain-button{align-self:center}.dialog-safety{border-top:1px solid var(--line);margin-top:26px;padding-top:20px;font-size:12px;display:block}.medicine-details{grid-template-columns:1.1fr 1fr;gap:8%;display:grid}.medicine-details h2{font-size:38px}.presentations h3{margin-top:0}.presentation{border-top:1px solid var(--line);align-items:center;gap:25px;padding:25px 0;display:flex}.presentation img{aspect-ratio:1.15;object-fit:contain;background:#fff;width:130px}.presentation strong{font-family:var(--serif);font-size:26px;font-weight:400}.presentation p{margin:10px 0 0;font-size:13px}.medicine-resources{background:#f5f5f5;grid-template-columns:1fr 1fr;gap:8%;display:grid}.medicine-resources h2{font-size:32px}.medicine-resources p{font-size:15px}.medicine-resources video{aspect-ratio:16/9;background:#1f4e79;width:100%;min-height:180px}.original-resource{text-underline-offset:4px;margin:24px 0;font-size:12px;text-decoration:underline;display:block}.medicine-safety{border-top:1px solid var(--line)}.medicine-safety>a{overflow-wrap:anywhere;margin:18px 0;font-size:22px;display:block}.medicine-safety>a:last-child{font-size:14px}.source-page{max-width:1000px;margin:auto}.source-page h2{margin:42px 0 20px;font-size:30px}.source-page h2:first-child{margin-top:0}.source-page ul{padding-left:20px}.source-page li{margin:15px 0}.source-page a{text-underline-offset:4px;text-decoration:underline}.source-page .context-note{margin-top:45px}.not-found{max-width:900px;padding:80px 8%}.not-found .eyebrow{margin:50px 0 25px}.not-found h1{font-family:var(--serif);font-size:45px}.not-found>div{gap:35px;margin-top:35px;display:flex}.not-found a{text-decoration:underline}.professional-dialog:not([open]){display:none}@media (max-width:820px){.medicine-details,.medicine-resources{grid-template-columns:1fr;gap:40px}.medicine-details h2{font-size:30px}.professional-dialog{padding:26px}.professional-dialog h2{font-size:27px}.medicine-safety h2{font-size:29px}.medicine-safety>a:last-child{font-size:12px}}.site .home-investors .document-row>span{color:#014694}.process-list span{color:#666}.documentary-photo{background-position:91% 63%}.section-nav{border-block:1px solid var(--line);flex-wrap:wrap;gap:20px 42px;margin:0 4.5%;padding:22px 0;font-size:14px;display:flex}.section-nav a{border-bottom:1px solid #0000;padding:7px 0}.section-nav a:hover{border-color:var(--cyan)}.original-title{max-width:850px;margin:24px 0;font-size:14px}.original-title summary,.image-transcript summary,.video-transcript summary{cursor:pointer;line-height:1.7}.original-title p{margin-top:14px}.image-transcript{background:#f5f5f5;margin-top:12px;padding:18px 22px;font-size:14px}.image-transcript p{color:var(--ink);margin-top:18px;margin-bottom:0}.video-transcript{margin-top:20px;font-size:14px}.video-transcript li{margin-top:14px;line-height:1.8}@media (max-width:600px){.section-nav{gap:10px 22px}.image-transcript{padding:16px}}.follow-qr{margin:18px 0;font-size:14px}.follow-qr summary{cursor:pointer;text-underline-offset:5px;text-decoration:underline}.follow-qr img{width:190px;max-width:100%;height:auto;margin-top:20px;display:block}.follow-section{border-top:1px solid var(--line);padding-top:36px;padding-bottom:36px}.source-supplement{border-top:1px solid var(--line);margin-top:42px;padding-top:28px}.source-supplement h2{font-size:22px;line-height:1.5}.source-version-note{margin:24px 0;font-size:14px}.source-version-note summary{cursor:pointer}.source-version-note p{margin-top:20px}:root{--ink:#1f4e79;--paper:#fff;--red:#ff2d16;--cyan:#35cbf5;--muted:#666;--line:#d3d3d3}.site{color:#1f4e79;background:#fff}.milestone-band,.footer{background:#1f4e79}.milestone-band .eyebrow,.footer a:hover{color:#35cbf5}.site .logo{filter:none;opacity:1;mix-blend-mode:normal;object-fit:contain;height:auto;transform:none}.label-clarification{margin:0 0 24px}.label-clarification h3{font-size:19px}.label-clarification p{font-size:14px}.science-source-links{flex-wrap:wrap;align-items:baseline;gap:16px 28px;margin-top:24px;display:flex}.science-source-links .source-note{margin:0}@property --tw-rotate-x{syntax:"*";inherits:false}@property --tw-rotate-y{syntax:"*";inherits:false}@property --tw-rotate-z{syntax:"*";inherits:false}@property --tw-skew-x{syntax:"*";inherits:false}@property --tw-skew-y{syntax:"*";inherits:false}@property --tw-border-style{syntax:"*";inherits:false;initial-value:solid}@property --tw-ordinal{syntax:"*";inherits:false}@property --tw-slashed-zero{syntax:"*";inherits:false}@property --tw-numeric-figure{syntax:"*";inherits:false}@property --tw-numeric-spacing{syntax:"*";inherits:false}@property --tw-numeric-fraction{syntax:"*";inherits:false}@property --tw-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-shadow-color{syntax:"*";inherits:false}@property --tw-shadow-alpha{syntax:"<percentage>";inherits:false;initial-value:100%}@property --tw-inset-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-inset-shadow-color{syntax:"*";inherits:false}@property --tw-inset-shadow-alpha{syntax:"<percentage>";inherits:false;initial-value:100%}@property --tw-ring-color{syntax:"*";inherits:false}@property --tw-ring-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-inset-ring-color{syntax:"*";inherits:false}@property --tw-inset-ring-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-ring-inset{syntax:"*";inherits:false}@property --tw-ring-offset-width{syntax:"<length>";inherits:false;initial-value:0}@property --tw-ring-offset-color{syntax:"*";inherits:false;initial-value:#fff}@property --tw-ring-offset-shadow{syntax:"*";inherits:false;initial-value:0 0 #0000}@property --tw-outline-style{syntax:"*";inherits:false;initial-value:solid}@property --tw-blur{syntax:"*";inherits:false}@property --tw-brightness{syntax:"*";inherits:false}@property --tw-contrast{syntax:"*";inherits:false}@property --tw-grayscale{syntax:"*";inherits:false}@property --tw-hue-rotate{syntax:"*";inherits:false}@property --tw-invert{syntax:"*";inherits:false}@property --tw-opacity{syntax:"*";inherits:false}@property --tw-saturate{syntax:"*";inherits:false}@property --tw-sepia{syntax:"*";inherits:false}@property --tw-drop-shadow{syntax:"*";inherits:false}@property --tw-drop-shadow-color{syntax:"*";inherits:false}@property --tw-drop-shadow-alpha{syntax:"<percentage>";inherits:false;initial-value:100%}@property --tw-drop-shadow-size{syntax:"*";inherits:false}.site{--body-text:#333;color:var(--body-text)}.site-header{border-bottom-color:#d3d3d3;min-height:112px}.desktop-nav a{color:var(--ink);font-weight:600}.desktop-nav a[aria-current=page]{border-bottom:0;padding-bottom:0}.header-actions{color:var(--ink)}.page-heading h1,.section h2,.split-heading h2{font-family:var(--sans);color:var(--ink);letter-spacing:-.045em;font-weight:600}.page-heading h1{max-width:1050px}.eyebrow{font-weight:600}.research-page{--chapter-space:clamp(64px, 7vw, 112px)}.research-page h1,.research-page h2,.research-page h3,.research-page h4{font-family:var(--sans);color:var(--ink)}.research-page h1,.research-page h2,.research-page h3{font-weight:600}.research-page p{line-height:1.7}.research-page a,.resource-nav a{text-underline-offset:4px}.research-hero{grid-template-columns:1.05fr 1fr;align-items:center;gap:6%;padding:76px 4.5% 72px;display:grid}.research-hero-copy>.eyebrow{border-left:4px solid var(--red);color:var(--ink);justify-content:space-between;margin-bottom:35px;padding-left:18px;display:flex}.research-hero-copy>.eyebrow span{letter-spacing:.16em;font-size:11px}.research-hero h1{letter-spacing:-.055em;margin:0 0 30px;font-size:clamp(40px,4.45vw,72px);line-height:1.06}.research-hero h1 em{font-style:normal}.research-hero-copy>p:not(.eyebrow){max-width:620px;font-size:17px}.research-hero-actions{color:var(--ink);flex-wrap:wrap;gap:25px;margin-top:32px;font-size:14px;font-weight:600;display:flex}.research-hero-actions a{border-bottom:1px solid var(--ink);align-items:center;gap:26px;padding:0 0 9px;display:flex}.molecule-composition{background:var(--ink);color:#fff;min-width:0;margin:0;padding:30px 30px 24px;position:relative}.research-hero>*{min-width:0}.fusion-illustration{width:100%;height:auto;margin:7px 0 0;display:block;overflow:visible}.fusion-mobile-key{display:none}@media (max-width:760px){.fusion-labels text[font-size="12"],.fusion-labels text[font-size="13"]{display:none}.fusion-labels text[font-weight="600"]{font-size:36px}.fusion-mobile-key{margin:0 0 23px;display:block}.fusion-mobile-key>div{grid-template-columns:62px 1fr;gap:15px;padding:7px 0;font-size:12px;line-height:1.5;display:grid}.fusion-mobile-key dt{font-weight:600}.fusion-mobile-key dd{margin:0}}.composition-note a{color:#fff;text-underline-offset:3px;text-decoration:underline}.clinical-program-sources{padding:0;list-style:none}.clinical-program-sources time{color:#666;margin-top:3px;font-size:10px;display:block}.composition-caption{letter-spacing:.06em;border-bottom:1px solid var(--cyan);justify-content:space-between;align-items:center;gap:22px;padding-bottom:18px;font-size:10px;display:flex}.composition-caption span:first-child{letter-spacing:0;white-space:nowrap;font-size:15px;font-weight:600}.composition-caption span:last-child{text-align:right;max-width:175px}.composition-components{grid-template-columns:1fr 25px 1fr;align-items:center;gap:9px;padding-top:42px;display:grid}.composition-components>div{flex-direction:column;min-height:160px;padding:20px;display:flex}.composition-glp{border-top:5px solid var(--red);color:var(--ink);background:#fff}.composition-fc{border-top:5px solid var(--cyan);background:var(--cyan);color:var(--ink)}.composition-components span{font-size:13px}.composition-components strong{letter-spacing:-.06em;white-space:nowrap;font-size:clamp(25px,3vw,45px);font-weight:600;line-height:1.4}.composition-components small{margin-top:auto;font-size:12px}.composition-components>.composition-plus{text-align:center;font-size:25px}.composition-connector{border:1px solid var(--cyan);border-top:0;width:56%;height:34px;margin:0 auto 33px;position:relative}.composition-connector span{border-left:1px solid var(--cyan);height:34px;position:absolute;bottom:-34px;left:50%}.composition-result{border-top:1px solid var(--cyan);text-align:center;padding-top:19px}.composition-result>span{letter-spacing:-.035em;font-size:clamp(22px,2.5vw,34px);font-weight:600}.composition-result p{margin:6px 0 0;font-size:13px}.molecule-composition .composition-note{color:#fff;opacity:.8;text-align:center;margin:34px 0 0;font-size:11px}.research-nav{z-index:20;border-top:1px solid var(--ink);background:#fff;border-bottom:1px solid #d3d3d3;grid-template-columns:repeat(5,1fr);margin:0 4.5%;display:grid;position:sticky;top:0}.research-nav a{color:var(--ink);border-right:1px solid #d3d3d3;align-items:center;gap:13px;padding:21px 12px;font-size:13px;font-weight:600;display:flex}.research-nav a:last-child{border-right:0}.research-nav a span{color:#666;font-size:11px;font-weight:400}.research-nav a:hover{background:var(--cyan)}.research-chapter{padding:var(--chapter-space) 4.5%;scroll-margin-top:85px}.chapter-heading{grid-template-columns:1.2fr 1fr;align-items:end;column-gap:9%;margin-bottom:45px;display:grid}.chapter-heading .eyebrow{color:var(--ink);grid-column:1/-1;margin-bottom:22px}.chapter-heading h2{letter-spacing:-.045em;white-space:pre-line;margin:0;font-size:clamp(30px,3.5vw,51px);line-height:1.13}.chapter-heading>p:last-child:not(.eyebrow){margin:0;font-size:16px}.foundation-grid{grid-template-columns:repeat(3,1fr);gap:40px;display:grid}.foundation-grid article{border-top:3px solid var(--ink);padding:20px 0 0}.chapter-index{color:var(--ink);font-size:13px}.foundation-grid h3{letter-spacing:-.025em;margin:34px 0 15px;font-size:23px;line-height:1.25}.foundation-grid p{margin:0;font-size:15px}.research-citation{color:var(--ink);border-top:1px solid #d3d3d3;flex-wrap:wrap;gap:15px 30px;margin-top:40px;padding-top:28px;font-size:12px;display:flex}.research-citation>span{color:#666}.clinical-chapter{background:#f5f5f5}.clinical-feature{border-top:5px solid var(--cyan);background:#fff;grid-template-columns:1.05fr 1fr;display:grid}.clinical-study-copy{padding:36px 40px}.study-kicker{color:#666;flex-wrap:wrap;align-items:center;gap:10px 25px;font-size:12px;display:flex}.study-kicker strong{color:var(--ink);letter-spacing:-.02em;font-size:17px}.clinical-study-copy h3{letter-spacing:-.025em;margin:35px 0 22px;font-size:30px;line-height:1.2}.clinical-study-copy p{font-size:15px}.clinical-study-copy>p+p{margin-top:12px}.research-button{background:var(--ink);color:#fff;justify-content:space-between;gap:40px;margin-top:14px;padding:14px 20px;font-size:13px;font-weight:600;display:inline-flex}.research-button:hover{background:var(--cyan);color:var(--ink)}.clinical-study-result{background:var(--ink);color:#fff;padding:42px 40px 24px}.clinical-study-result h4{color:#fff;margin:16px 0 0;font-size:23px;font-weight:600;line-height:1.3}.clinical-study-result .eyebrow{color:#fff;font-size:11px}.chart-unit{margin:5px 0 25px;font-size:12px}.study-bar{margin:22px 0}.study-bar>span{margin-bottom:9px;font-size:12px;display:block}.study-bar>div{padding-right:68px;display:block;position:relative}.study-bar i{background:var(--cyan);flex-shrink:1;height:36px;display:block}.study-bar strong{letter-spacing:-.03em;flex-shrink:0;font-size:30px;position:absolute;top:0;right:0}.study-bar.comparator i{background:#fff}.clinical-study-result>p:last-child{margin-top:30px;font-size:12px}.clinical-study-note{color:#666;border:1px solid #d3d3d3;border-top:0;grid-column:1/-1;margin:0;padding:20px 40px;font-size:12px}.clinical-tracks{grid-template-columns:repeat(3,1fr);gap:40px;margin-top:45px;display:grid}.clinical-tracks article{border-top:1px solid #d3d3d3;padding-top:25px}.track-dot{background:var(--ink);width:12px;height:12px;display:block}.track-dot.investigational{background:var(--cyan)}.clinical-tracks h3{letter-spacing:-.025em;margin:18px 0 12px;font-size:23px}.clinical-tracks p{font-size:14px}.research-date{color:#666;margin:32px 0 0;font-size:12px}.research-date a{color:var(--ink);text-decoration:underline}.pipeline-chapter .chapter-heading{margin-bottom:38px}.research-page .filter-tabs{border:0;flex-wrap:wrap;gap:8px;margin:0;display:flex}.research-page .filter-tabs button{font:500 13px var(--sans);color:var(--ink);background:#fff;border:1px solid #d3d3d3;border-radius:0;min-height:44px;padding:12px 15px}.research-page .filter-tabs button[aria-pressed=true]{background:var(--ink);color:#fff;border-color:var(--ink)}.research-page .filter-tabs button:hover{border-color:var(--ink)}.pipeline-controls{justify-content:space-between;align-items:center;gap:16px;display:flex}.results-count{color:#666;flex-shrink:0;font-size:12px}.research-page .pipeline-legend{border-bottom:0;justify-content:space-between;align-items:baseline;gap:35px;margin:0;padding:18px 0;display:flex}.research-page .pipeline-legend p{max-width:810px;margin:0;font-size:12px}.pipeline-legend>a{white-space:nowrap;color:var(--ink);font-size:12px}.pipeline-collection{margin-top:35px}.pipeline-collection>header{background:var(--ink);color:#fff;justify-content:space-between;gap:60px;padding:26px 28px;display:flex}.pipeline-collection>header>div{flex:1;align-items:baseline;gap:24px;display:flex}.collection-label{color:var(--cyan);font-size:12px}.pipeline-collection>header h3{letter-spacing:-.03em;color:#fff;margin:0;font-size:27px;line-height:1.2}.pipeline-collection>header p{flex:1;max-width:480px;margin:0;font-size:13px}.research-page .pipeline-table{border:0;margin:0}.research-page .pipeline-labels{color:#666;background:#f5f5f5;grid-template-columns:.9fr 1fr 1.5fr;gap:38px;padding:15px 28px;font-size:11px;display:grid}.research-page .pipeline-row{background:#fff;border:0;border-bottom:1px solid #d3d3d3;grid-template-columns:.9fr 1fr 1.5fr;align-items:start;gap:38px;padding:25px 28px;display:grid}.research-page .pipeline-row.marketed{border-left:4px solid var(--cyan);padding-left:24px}.pipeline-row h4{margin:0 0 6px;font-size:16px;font-weight:600;line-height:1.4}.research-page .pipeline-row p{margin:5px 0;font-size:13px;line-height:1.6}.research-page .pipeline-row .small-label{color:#666;text-transform:none;letter-spacing:0;font-size:12px}.research-page .pipeline-row .source-note{color:var(--ink);margin-top:5px;display:inline-block;font-size:11px!important}.status-badge{color:var(--ink);border:1px solid #d3d3d3;margin-bottom:4px;padding:4px 8px;font-size:11px;display:inline-block}.stage-marketed{background:var(--cyan);border-color:var(--cyan)}.collection-other>header{color:var(--body-text);border-top:4px solid var(--red);background:#f5f5f5}.collection-other>header h3,.collection-other .collection-label{color:var(--ink)}.collection-companion>header{color:var(--body-text);border-top:4px solid var(--cyan);background:#fff;border-bottom:1px solid #d3d3d3}.collection-companion>header h3,.collection-companion .collection-label{color:var(--ink)}.platform-chapter{background:#f5f5f5}.platform-pillars{grid-template-columns:repeat(3,1fr);gap:38px;display:grid}.platform-pillars article{border-top:1px solid var(--ink);padding-top:20px}.platform-pillars article>span{color:var(--ink);font-size:13px}.platform-pillars h3{letter-spacing:-.025em;margin:30px 0 15px;font-size:24px;line-height:1.25}.platform-pillars p{font-size:14px}.platform-pillars a{color:var(--ink);font-size:13px}.platform-operations{border-top:1px solid #d3d3d3;grid-template-columns:1.2fr 1fr;align-items:center;gap:6%;margin-top:54px;padding-top:64px;display:grid}.platform-operations figure{margin:0}.platform-operations img{width:100%;height:auto;display:block}.platform-operations figcaption{color:#666;margin-top:12px;font-size:11px}.platform-operations h3{letter-spacing:-.035em;margin:20px 0;font-size:32px;line-height:1.2}.platform-operations p{font-size:14px}.platform-operations a{color:var(--ink);font-size:13px}.research-library{grid-template-columns:repeat(2,1fr);column-gap:70px;display:grid}.research-paper{border-top:1px solid var(--ink);flex-direction:column;margin-top:35px;padding:25px 0 35px;display:flex}.paper-meta{color:var(--ink);justify-content:space-between;gap:20px;font-size:11px;display:flex}.paper-meta time{font-weight:600}.research-paper h3{letter-spacing:-.025em;margin:25px 0 7px;font-size:26px;line-height:1.25}.research-paper .paper-journal{color:#666;margin:0 0 8px;font-size:12px}.paper-publication-link{color:var(--ink);align-self:flex-start;margin-bottom:25px;font-size:13px;font-weight:600}.research-paper h4{margin:0;font-size:15px;font-weight:600;line-height:1.5}.research-paper>p{font-size:14px}.research-paper .paper-limit{border-left:3px solid var(--cyan);color:#666;margin:8px 0 24px;padding-left:14px;font-size:12px}.paper-links{color:var(--ink);gap:25px;margin-top:auto;font-size:13px;font-weight:600;display:flex}.paper-copy{flex-direction:column;height:100%;display:flex}.paper-copy>p{font-size:14px}.research-paper-illustrated{grid-column:1/-1;grid-template-columns:1.08fr 1fr;align-items:center;gap:7%;padding:38px 0;display:grid}.paper-figure{border:1px solid #d3d3d3;margin:0;padding:15px}.paper-figure img{width:100%;height:auto;display:block}.paper-figure figcaption{color:#666;margin-top:15px;font-size:11px}.research-paper-illustrated h3{font-size:31px}@media (max-width:760px){.research-paper-illustrated{grid-template-columns:1fr;gap:25px}.research-paper-illustrated h3{font-size:26px}.research-paper-illustrated .paper-copy{height:auto}}.research-next{background:var(--ink);color:#fff;border-top:5px solid var(--cyan);justify-content:space-between;align-items:flex-end;gap:40px;margin:0 4.5% 70px;padding:50px;display:flex}.research-next h2{color:#fff;letter-spacing:-.04em;white-space:pre-line;margin:18px 0 0;font-size:38px;line-height:1.15}.research-next>a{border-bottom:1px solid var(--cyan);justify-content:space-between;gap:30px;padding-bottom:12px;font-size:14px;display:flex}.clinical-program-map{margin-top:50px}.clinical-program-heading{grid-template-columns:1fr 1.2fr;gap:15px 60px;margin-bottom:30px;display:grid}.clinical-program-heading .eyebrow{grid-column:1/-1;margin:0}.clinical-program-heading h3{letter-spacing:-.03em;margin:0;font-size:30px;line-height:1.2}.clinical-program-heading>p:last-child{margin:0;font-size:14px}.clinical-program-columns,.clinical-program-item{grid-template-columns:.8fr 1.25fr 1.1fr;gap:40px;display:grid}.clinical-program-columns{border-top:1px solid var(--ink);color:#666;padding:14px 0;font-size:11px}.clinical-program-list{margin:0;padding:0;list-style:none}.clinical-program-item{border-top:1px solid #d3d3d3;padding:25px 0}.clinical-program-item h4{margin:10px 0;font-size:19px;font-weight:600;line-height:1.3}.clinical-program-number{color:#666;font-size:11px}.clinical-program-item p{margin:0 0 12px;font-size:13px}.clinical-program-identity p{color:#666;font-size:12px}.clinical-program-item .clinical-program-setting{color:var(--ink);font-weight:600}.clinical-program-sources{color:var(--ink);flex-direction:column;gap:10px;font-size:11px;display:flex}.clinical-program-sources a{text-decoration:underline}.company-source-context{border-top:1px solid #d3d3d3;border-bottom:1px solid #d3d3d3;margin:30px 0;padding:25px 0}.company-source-context h3{font:600 24px var(--sans);color:var(--ink);margin:0 0 18px;line-height:1.25}.company-source-context a{color:var(--ink);font-size:12px}@media (max-width:760px){.clinical-program-heading{display:block}.clinical-program-heading h3{margin:18px 0;font-size:28px}.clinical-program-columns{display:none}.clinical-program-item{grid-template-columns:1fr;gap:10px}.clinical-program-identity{grid-template-columns:25px 1fr;align-items:baseline;gap:4px 12px;display:grid}.clinical-program-identity h4{margin:0}.clinical-program-identity p{grid-column:2}.clinical-program-question,.clinical-program-evidence{margin-left:37px}}.resource-heading{padding-top:60px;padding-bottom:42px}.resource-heading h1{letter-spacing:-.055em;margin-bottom:20px;font-size:clamp(60px,8vw,110px);line-height:1}.medicine-access,.medicine-access-pending{min-height:70vh;color:var(--ink)}.medicine-access-pending>a{text-underline-offset:4px;text-decoration:underline}.resource-heading .resource-generic{color:var(--ink);max-width:900px;margin-bottom:18px;font-size:24px}.resource-heading>p:last-child{max-width:850px;font-size:16px}.resource-nav{border-top:1px solid var(--ink);color:var(--ink);border-bottom:1px solid #d3d3d3;gap:36px;margin:0 4.5%;padding:19px 0;font-size:13px;font-weight:600;display:flex}.medicine-details.resource-overview{grid-template-columns:.95fr 1.05fr;align-items:center;gap:6%;padding-top:60px;display:grid}.resource-overview h2{margin:20px 0;font-size:39px;line-height:1.15}.resource-overview-copy>p{font-size:15px;line-height:1.7}.resource-facts{margin-top:28px}.resource-facts>div{border-top:1px solid #d3d3d3;grid-template-columns:1fr 1.3fr;gap:20px;padding:12px 0;font-size:13px;display:grid}.resource-facts dt{color:#666}.resource-facts dd{color:var(--ink);margin:0}.resource-sources{color:var(--ink);grid-template-columns:1fr auto;gap:8px 20px;margin-top:24px;font-size:11px;display:grid}.resource-sources span{color:#666}.resource-pack-hero{border-bottom:5px solid var(--cyan);margin:0;padding:50px 15px 24px}.resource-pack-hero img{width:100%;height:auto;display:block}.resource-pack-hero figcaption{color:#666;margin-top:40px;font-size:11px}.resource-treatment{background:var(--ink);color:#fff}.resource-treatment .eyebrow,.resource-treatment h2,.resource-treatment h3{color:#fff}.resource-section-heading{max-width:720px;margin-bottom:35px}.resource-section-heading h2{margin:22px 0;font-size:39px;line-height:1.15}.resource-section-heading p{font-size:15px;line-height:1.7}.resource-treatment-grid{grid-template-columns:1fr 1fr;gap:65px;display:grid}.resource-index{color:var(--cyan);font-size:13px}.resource-treatment-grid h3{margin:22px 0 15px;font-size:26px;font-weight:600;line-height:1.25}.resource-treatment-grid p{max-width:530px;font-size:15px;line-height:1.7}.resource-treatment>.source-note{margin-top:40px;color:#fff!important;font-size:12px!important}.resource-presentation-grid{grid-template-columns:1fr 1fr;gap:65px;display:grid}.presentation.resource-presentation{border-top:1px solid #d3d3d3;flex-direction:column;gap:20px;padding:25px 0;display:flex}.resource-presentation img{aspect-ratio:auto;width:100%;height:auto;display:block}.resource-presentation figcaption{color:#666;flex-wrap:wrap;justify-content:space-between;align-items:baseline;gap:8px 20px;width:100%;font-size:13px;display:flex}.resource-presentation figcaption strong{font-family:var(--sans);color:var(--ink);font-size:25px;font-weight:600}.resource-presentation figcaption p{margin:0;font-size:12px}.resource-document{background:#f5f5f5;grid-template-columns:1fr 1fr;align-items:start;gap:8%;display:grid}.resource-document-intro h2{margin:24px 0;font-size:43px;line-height:1.15}.resource-document-intro p{font-size:15px;line-height:1.7}.resource-document-card{border-top:5px solid var(--red);background:#fff;padding:30px}.resource-document-format{color:var(--ink);justify-content:space-between;align-items:center;gap:25px;font-size:12px;display:flex}.resource-document-card h3{color:var(--ink);margin:30px 0;font-size:24px;font-weight:600;line-height:1.35}.resource-document-meta>div{border-top:1px solid #d3d3d3;grid-template-columns:1fr 1.4fr;gap:24px;padding:12px 0;font-size:12px;display:grid}.resource-document-meta dd{margin:0}.resource-document-meta dt{color:#666}.resource-document-card .primary-button{margin-top:20px;font-size:13px}.resource-document-card .original-resource{margin-top:18px;font-size:12px;display:block}.medicine-resources.resource-guidance{grid-template-columns:.65fr 1.35fr;align-items:start;gap:6%;display:grid}.resource-guidance .resource-section-heading h2{font-size:36px}.resource-guidance .resource-video-meta{color:#666;font-size:12px}.resource-video-content{min-width:0}.resource-video-content video{width:100%;margin-top:25px;display:block}.resource-video-content .label-clarification{border-left:4px solid var(--red);background:#f5f5f5;margin:0;padding:22px}.resource-video-content .label-clarification h3{font-family:var(--sans);color:var(--ink);font-size:18px;line-height:1.3}.resource-video-content .label-clarification p{font-size:13px;line-height:1.65}.resource-video-content .label-clarification a{font-size:12px}.resource-chapters{border-bottom:1px solid #d3d3d3;grid-template-columns:repeat(4,1fr);display:grid}.resource-chapters button{text-align:left;font:12px var(--sans);color:var(--ink);cursor:pointer;background:#fff;border:0;border-right:1px solid #d3d3d3;padding:16px 10px}.resource-chapters button:last-child{border-right:0}.resource-chapters button span{color:#666;margin-bottom:6px;font-size:11px;display:block}.resource-chapters button:hover{background:#f5f5f5}.resource-transcript-time{font-variant-numeric:tabular-nums;color:var(--ink);margin-right:8px;font-size:12px;font-weight:600}.resource-safety{background:var(--ink);color:#fff;border-top:5px solid var(--cyan)}.resource-safety h2,.resource-safety .eyebrow,.resource-safety a{color:#fff}.resource-safety h2{font-size:38px}.resource-safety a{overflow-wrap:anywhere;width:fit-content;display:block}.resource-safety a[href^=tel]{letter-spacing:-.035em;margin:16px 0;font-size:36px;font-weight:600}.resource-source-statement{border-left:3px solid var(--cyan);margin:25px 0;padding-left:18px}.resource-source-statement .eyebrow{font-size:10px}.resource-source-statement blockquote{margin:12px 0;font-size:14px;line-height:1.65}.resource-source-statement>a{color:var(--ink);font-size:12px}.pipeline-rights{border-left:3px solid var(--cyan);background:#f5f5f5;margin:5px 0 30px;padding:18px 22px;font-size:13px}.pipeline-rights a,.platform-proposition a{color:var(--ink);text-decoration:underline}.pipeline-history{border:1px solid #d3d3d3;grid-template-columns:1fr 1fr;gap:20px 60px;margin-top:40px;padding:32px;display:grid}.pipeline-history h3{letter-spacing:-.025em;margin:20px 0;font-size:25px;line-height:1.3}.pipeline-history p,.pipeline-history li{font-size:13px;line-height:1.7}.pipeline-history ul{margin:0;padding-left:18px}.pipeline-history li{margin-bottom:12px}.pipeline-history details{border-top:1px solid #d3d3d3;grid-column:1/-1;padding-top:20px}.pipeline-history summary{cursor:pointer;color:var(--ink);font-size:14px;font-weight:600}.pipeline-history figure{margin:25px 0}.pipeline-history img{width:100%;height:auto;display:block}.pipeline-history figcaption{color:#666;margin-top:15px;font-size:12px}.historical-pipeline-text{max-width:1000px}.platform-proposition{border-left:3px solid var(--cyan);max-width:1000px;margin:38px 0 0;padding-left:20px;font-size:14px}.platform-operations{margin-top:35px;padding-top:35px}.front-development-drawing .front-drawing-note{border-top:1px solid #ffffff50;grid-column:1/-1;margin:-12px 0 0;padding-top:15px;font-size:11px}.front-development-drawing .front-drawing-note a{font-size:11px}.front-composition-input.front-input-glp{border-left-color:var(--red)}.front-branch-heading h3{text-transform:none;letter-spacing:-.015em}.front-branch-heading .front-label{color:var(--cyan);font-size:10px}.front-research-paths{margin:0;padding:0;list-style:none}.front-research-paths li{padding:12px 0}.front-research-paths strong{font-size:13px;font-weight:500;display:block}.front-research-paths span{margin-top:5px;font-size:11px;display:block}.front-research-paths p{margin:5px 0;font-size:12px}@media (max-width:760px){.front-composition-inputs>.front-label{grid-column:1/-1}.front-development-drawing .front-drawing-note{margin-top:0}}.front-caption-rail{grid-column:1/-1;justify-content:space-between;align-items:end;gap:70px;margin:27px 0 38px;display:flex}.front-caption-rail .front-intro{max-width:775px}.front-caption-rail .front-actions{flex-shrink:0;margin:0!important}.front-development-drawing{background:var(--ink);color:#fff;border-top:4px solid var(--cyan);grid-template-columns:.75fr 1.1fr 1.2fr;align-items:center;gap:70px;padding:42px;display:grid;position:relative}.front-development-drawing h2,.front-development-drawing h3,.front-development-drawing a,.front-development-drawing .front-label,.front-page .front-development-drawing h2,.front-page .front-development-drawing h3{color:#fff}.front-development-drawing p{font-size:13px;line-height:1.6}.front-development-drawing a{text-underline-offset:4px;font-size:12px;text-decoration:underline}.front-composition-inputs,.front-medicine-node,.front-development-branches{min-width:0;position:relative}.front-composition-inputs:after{content:"";border:1px solid var(--cyan);border-left:0;width:22px;position:absolute;top:18%;bottom:33%;right:-34px}.front-composition-input{border-left:4px solid var(--cyan);padding-left:17px}.front-composition-input:first-child{border-left-color:var(--red)}.front-composition-input span{font-size:12px}.front-composition-input strong{letter-spacing:-.025em;margin:4px 0;font-size:31px;line-height:1.2;display:block}.front-composition-plus{color:var(--cyan);padding:7px 17px;font-size:23px;display:block}.front-composition-note{max-width:260px;margin:25px 0 15px;font-size:11px!important}.front-medicine-node:before{content:"";border-top:1px solid var(--cyan);width:27px;position:absolute;top:44%;left:-36px}.front-medicine-node h2{letter-spacing:-.035em;margin:16px 0 20px;font-size:36px;line-height:1.14}.front-medicine-node>p{max-width:310px}.front-medicine-node a{margin-top:13px;display:inline-block}.front-development-branches{border-left:1px solid var(--cyan);padding-left:30px}.front-development-branches:before{content:"";border-top:1px solid var(--cyan);width:40px;position:absolute;top:50%;left:-41px}.front-approved-branch{padding-bottom:24px}.front-research-branch{border-top:1px dashed var(--cyan);padding-top:22px}.front-branch-heading{color:var(--cyan);text-transform:uppercase;letter-spacing:.04em;margin:0;font-weight:600;font-size:11px!important}.front-development-branches h3{letter-spacing:-.015em;margin:12px 0;font-size:22px;line-height:1.25}.front-territory-dates{margin:17px 0}.front-territory-dates>div{justify-content:space-between;gap:22px;margin-bottom:10px;font-size:12px;display:flex}.front-territory-dates dt,.front-territory-dates dd{margin:0}.front-territory-dates dd{text-align:right}.front-drawing-source{opacity:.85;font-size:10px!important}@media (min-width:761px){.front-hero:has(.front-development-drawing) .front-hero-copy{display:block}.front-hero:has(.front-development-drawing) h1{max-width:1300px;font-size:clamp(48px,5vw,82px)}}@media (max-width:1050px){.front-caption-rail{gap:35px}.front-caption-rail .front-actions{flex-direction:column;align-items:start;gap:12px}.front-development-drawing{grid-template-columns:.7fr 1fr 1.15fr;gap:40px;padding:30px}.front-composition-input strong{font-size:25px}.front-medicine-node h2{font-size:29px}.front-development-branches{padding-left:18px}.front-composition-inputs:after{width:14px;right:-24px}.front-medicine-node:before{width:12px;left:-16px}.front-development-branches:before{width:22px;left:-23px}}@media (max-width:760px){.front-caption-rail{margin:20px 0 30px;display:block}.front-caption-rail .front-actions{flex-direction:row;gap:20px;margin-top:25px!important}.front-development-drawing{grid-template-columns:1fr;gap:35px;padding:28px 25px}.front-composition-inputs{grid-template-columns:1fr auto 1fr;gap:10px;display:grid}.front-composition-input{padding-left:12px}.front-composition-input strong{font-size:23px}.front-composition-plus{align-self:center;padding:10px 0}.front-composition-note,.front-composition-inputs>a{grid-column:1/-1;margin:8px 0}.front-composition-inputs:after{display:none}.front-medicine-node{border-top:1px solid var(--cyan);padding-top:26px}.front-medicine-node:before{border-top:0;border-left:1px solid var(--cyan);width:1px;height:22px;top:-23px;left:50%}.front-medicine-node h2{font-size:33px}.front-development-branches:before{display:none}.front-development-branches{padding-left:20px}.front-drawing-source{font-size:11px!important}}.front-page{color:var(--body-text)}.front-page h1,.front-page h2,.front-page h3{font-family:var(--sans);color:var(--ink);font-weight:600}.front-page p{line-height:1.7}.front-kicker{color:var(--ink);letter-spacing:.07em;text-transform:uppercase;font-size:11px;font-weight:600}.front-hero{padding:55px 4.5% 0}.front-hero-copy{grid-template-columns:1.65fr 1fr;align-items:end;column-gap:8%;display:grid}.front-hero-copy .front-kicker{border-left:4px solid var(--red);grid-column:1/-1;margin:5px 0 27px;padding-left:16px}.front-hero h1{letter-spacing:-.06em;margin:0;font-size:clamp(48px,5.1vw,82px);font-weight:600;line-height:1.03}.front-hero h1 span{display:block}.front-intro{max-width:560px;margin:0;font-size:16px}.front-actions{flex-wrap:wrap;align-items:center;gap:30px;display:flex}.front-hero .front-actions{grid-column:1/-1;margin:30px 0 42px}.front-button{background:var(--ink);color:#fff;align-items:center;gap:35px;padding:14px 22px;font-size:13px;font-weight:600;display:inline-flex}.front-button:hover{background:var(--cyan);color:var(--ink)}.front-link{color:var(--ink);border-bottom:1px solid #d3d3d3;align-items:center;gap:20px;padding-bottom:6px;font-size:13px;font-weight:600;display:inline-flex}.front-link:hover{border-bottom-color:var(--ink)}.front-journey{background:var(--ink);color:#fff;grid-template-columns:repeat(3,1fr);margin:0;padding:0;list-style:none;display:grid}.front-journey li{border-top:5px solid var(--cyan);flex-direction:column;padding:28px 30px;display:flex;position:relative}.front-journey li:first-child{border-top-color:var(--red)}.front-journey li+li{border-left:1px solid #ffffff50}.front-journey h2{color:#fff;letter-spacing:-.03em;margin:20px 0 15px;font-size:29px;line-height:1.2}.front-journey h2 span{color:var(--cyan);display:block}.front-journey p{max-width:350px;margin:0 0 22px;font-size:13px}.front-journey .front-label{color:#fff;opacity:.85;margin:0;font-size:11px}.front-journey a{color:#fff;text-underline-offset:5px;margin-top:auto;font-size:12px;text-decoration:underline}.front-journey-use{background:var(--cyan)}.front-journey-use h2,.front-journey-use p,.front-journey-use a,.front-journey-use .front-label{color:var(--ink)}.front-milestones{grid-template-columns:repeat(3,1fr) auto;align-items:center;gap:35px;padding:25px 4.5% 30px;display:grid}.front-milestones>div{align-items:baseline;gap:18px;display:flex}.front-year{letter-spacing:-.03em;color:var(--ink);white-space:nowrap;font-size:19px;font-weight:600}.front-milestones p{margin:0;font-size:11px}.front-milestones>a{color:var(--ink);gap:22px;font-size:12px;display:flex}.front-section{padding:80px 4.5%}.front-heading{justify-content:space-between;align-items:end;gap:60px;margin-bottom:38px;display:flex}.front-heading h2{letter-spacing:-.04em;max-width:820px;margin:20px 0 0;font-size:43px;line-height:1.15}.front-heading>.front-link{flex-shrink:0}.front-label{text-transform:uppercase;letter-spacing:.04em;color:var(--ink);font-size:11px}.front-programs{border-top:1px solid #d3d3d3}.front-program-layout{grid-template-columns:.85fr 1.15fr;gap:9%;display:grid}.front-program-intro{border-top:4px solid var(--cyan);padding-top:24px}.front-program-intro h3{letter-spacing:-.04em;margin:20px 0;font-size:38px;line-height:1.12}.front-program-intro>p{font-size:15px}.front-program-intro .front-link{margin-top:20px}.front-program{border-top:1px solid #d3d3d3;padding:22px 0}.front-program:first-child{border:0;padding-top:0}.front-program-title{justify-content:space-between;align-items:baseline;gap:20px;display:flex}.front-program-title h3{letter-spacing:-.015em;margin:0;font-size:20px;line-height:1.3}.front-status{color:var(--ink);border:1px solid #d3d3d3;flex-shrink:0;padding:5px 8px;font-size:11px}.front-program-marketed .front-status{background:var(--cyan);border-color:var(--cyan)}.front-program>p{margin:10px 0;font-size:13px}.front-program .front-territory,.front-program .front-program-date{color:#666;font-size:11px}.front-source-note{color:#666;margin:30px 0 0;font-size:11px}.front-source-note a{color:var(--ink);text-underline-offset:3px;text-decoration:underline}.front-research{background:#f5f5f5}.front-section-intro{max-width:870px;font-size:16px}.front-research-list{grid-template-columns:repeat(3,1fr);gap:40px;margin-top:35px;display:grid}.front-research-item{border-top:1px solid var(--ink);flex-direction:column;padding-top:22px;display:flex}.front-research-meta{color:#666;justify-content:space-between;align-items:baseline;gap:25px;font-size:11px;display:flex}.front-research-meta time{color:var(--ink);font-weight:600}.front-research-item h3{letter-spacing:-.025em;margin:26px 0 15px;font-size:23px;line-height:1.3}.front-research-item p{font-size:14px}.front-research-item .front-research-scope{color:#666;border-left:3px solid var(--cyan);margin-bottom:24px;padding-left:13px;font-size:12px}.front-research-item>a{color:var(--ink);justify-content:space-between;gap:20px;margin-top:auto;font-size:12px;display:flex}.front-platform-link{margin-top:38px}.front-company{grid-template-columns:1.05fr 1fr;align-items:start;gap:7%;display:grid}.front-company-photo{margin:0}.front-company-photo img{aspect-ratio:1;object-fit:cover;width:100%;height:auto;display:block}.front-company-photo figcaption{color:#666;margin-top:13px;font-size:11px}.front-company h2{letter-spacing:-.04em;margin:24px 0;font-size:39px;line-height:1.15}.front-company-copy>p{font-size:14px}.front-company .front-actions{gap:20px;margin-top:24px}.front-founder{border-top:1px solid #d3d3d3;gap:23px;margin-top:30px;padding-top:28px;display:flex}.front-founder>img{object-fit:cover;object-position:top;width:84px;height:110px}.front-founder .front-label{margin:0;font-size:10px}.front-founder h3{letter-spacing:-.02em;margin:10px 0;font-size:20px}.front-founder p{font-size:12px}.front-founder a{color:var(--ink);font-size:12px}.front-news{border-top:1px solid #d3d3d3}.front-news-grid{grid-template-columns:1.1fr 1fr;gap:7%;display:grid}.front-news-feature{display:block}.front-news-feature figure{margin:0 0 20px}.front-news-feature img{aspect-ratio:1.9;object-fit:cover;width:100%;height:auto;display:block}.front-news-feature figcaption{color:#666;margin-top:10px;font-size:11px}.front-news-feature h3{letter-spacing:-.03em;margin:18px 0;font-size:28px;line-height:1.25}.front-news-feature p{font-size:14px}.front-news-feature time,.front-news-list time{color:#666;font-size:11px}.front-news-list>a,.front-news-list>article{border-top:1px solid #d3d3d3;padding:22px 0;display:block}.front-news-list>:first-child{border-top:1px solid var(--ink)}.front-news-list h3{letter-spacing:-.015em;margin:10px 0;font-size:20px;line-height:1.35}.front-news-list>a>span{color:var(--ink);font-size:12px}.front-investors{background:var(--ink);color:#fff}.front-investors .front-kicker,.front-investors h2,.front-investors h3,.front-investors .front-link,.front-investors a,.front-investors .front-label{color:#fff}.front-investors .front-heading{margin-bottom:35px}.front-investor-grid{grid-template-columns:1fr 1fr;gap:7%;display:grid}.front-results{border-top:3px solid var(--cyan);padding:25px 0}.front-results h3{letter-spacing:-.03em;margin:20px 0;font-size:28px}.front-results p{font-size:14px}.front-results time{font-size:12px}.front-editions{flex-wrap:wrap;gap:25px;margin-top:25px;font-size:13px;display:flex}.front-disclosures>article,.front-disclosures>a{border-top:1px solid #ffffff60;padding:19px 0;display:block}.front-disclosures time{font-size:11px}.front-disclosures h3{margin:10px 0;font-size:17px;line-height:1.35}.front-disclosures .front-editions{margin-top:12px;font-size:11px}.front-resources{grid-template-columns:repeat(2,1fr);gap:65px;padding:45px 4.5%;display:grid}.front-resources>div{border-top:1px solid #d3d3d3;padding-top:20px}.front-resources h2{letter-spacing:-.025em;max-width:500px;font-size:25px;line-height:1.25}.front-feature-body{padding-top:22px}.front-news-list h3 a{justify-content:space-between;align-items:start;gap:30px;display:flex}.front-news-list h3 a span{font-size:16px}.front-resources>a{color:var(--ink);border-top:1px solid #d3d3d3;padding-top:20px;display:block}.front-resources h3{margin:12px 0;font-size:20px}.front-resources p{font-size:13px}.company-local-nav{border-top:1px solid var(--ink);color:var(--ink);border-bottom:1px solid #d3d3d3;gap:28px;margin:0 4.5%;padding:20px 0;font-size:13px;font-weight:600;display:flex;overflow-x:auto}.company-heading h1{margin:22px 0 20px;font-size:clamp(48px,5.5vw,80px)}.company-heading>p:not(.eyebrow){max-width:740px;margin-bottom:0}.company-facts{color:var(--ink);border-top:1px solid #d3d3d3;grid-template-columns:repeat(3,1fr);gap:30px;margin:38px 0 0;padding-top:22px;display:grid}.company-facts dt{letter-spacing:-.03em;font-size:25px;font-weight:600}.company-facts dd{color:#333;margin:6px 0 0;font-size:13px}.company-founder figure{max-width:260px;margin:30px 0 0}.company-founder img{width:100%;height:auto}.company-founder figcaption a{color:var(--ink);font-size:15px;font-weight:600}.company-founder figcaption span{margin-top:4px;font-size:12px;display:block}.institution-listed{border-top:1px solid #d3d3d3;padding:22px 0}.institution-listed .source-institutions{width:180px;height:auto;margin:22px 0 0}.company-local-nav a{flex-shrink:0}.investor-company-context{border-left:4px solid var(--cyan);background:#f5f5f5;margin:0 4.5% 40px;padding:30px;font-size:14px;line-height:1.7}.investor-company-context h2{font:600 26px var(--sans);color:var(--ink);margin:0 0 20px}.investor-results-link{color:var(--ink);flex-wrap:wrap;align-items:baseline;gap:12px 30px;margin-top:28px;display:flex}.investor-results-link a:first-child{text-underline-offset:5px;font-weight:600;text-decoration:underline}.investor-results-link a:last-child{font-size:13px}@media (max-width:760px){.company-heading{padding-top:40px;padding-bottom:30px}.company-facts{grid-template-columns:1fr;gap:15px;margin-top:25px}.company-facts>div{grid-template-columns:100px 1fr;align-items:baseline;gap:15px;display:grid}.company-facts dt{font-size:21px}.company-facts dd{margin:0;font-size:12px}.company-local-nav{flex-wrap:wrap;gap:8px 25px;padding:13px 0}.company-local-nav a{align-items:center;min-height:36px;display:flex}.company-intro{padding-top:40px}.company-founder figure{grid-template-columns:100px 1fr;align-items:center;gap:20px;max-width:none;display:grid}.company-founder figcaption{margin-top:0}.investors-heading{padding-top:40px;padding-bottom:30px}.investor-results-link{margin-top:20px}}@media (max-width:1050px){.front-hero-copy{grid-template-columns:1.5fr 1fr;gap:20px 5%}.front-hero h1{font-size:48px}.front-journey li{padding:24px}.front-journey h2{font-size:25px}.front-milestones{gap:25px}.front-milestones>div{display:block}.front-heading h2{font-size:37px}.front-program-layout{gap:6%}.front-program-title{align-items:start}.front-program-title h3{font-size:18px}.front-research-list{gap:25px}.front-company{gap:5%}.front-company h2{font-size:33px}.front-news-feature h3{font-size:25px}}@media (max-width:760px){.pipeline-history{padding:23px;display:block}.pipeline-history>ul{margin:25px 0}.pipeline-history h3{font-size:24px}.front-hero{padding-top:37px}.front-hero-copy{display:block}.front-hero h1{font-size:clamp(37px,9.7vw,63px);line-height:1.07}.front-intro{margin-top:24px;font-size:15px}.front-hero .front-actions{margin:25px 0 33px}.front-journey{grid-template-columns:1fr}.front-journey li{border-top:0;border-left:4px solid var(--cyan);padding:25px}.front-journey li:first-child{border-left-color:var(--red)}.front-journey li+li{border-left:4px solid var(--cyan);border-top:1px solid #ffffff60}.front-journey h2{margin:16px 0;font-size:27px}.front-journey h2 span{display:inline}.front-journey p{margin-bottom:20px}.front-milestones{grid-template-columns:1fr;gap:0;padding-top:15px;padding-bottom:15px}.front-milestones>div{border-bottom:1px solid #d3d3d3;grid-template-columns:95px 1fr;padding:15px 0;display:grid}.front-milestones>a{justify-content:space-between;padding-top:18px}.front-section{padding:58px 4.5%}.front-heading{margin-bottom:30px;display:block}.front-heading h2{font-size:33px}.front-heading .front-link{margin-top:25px}.front-program-layout,.front-research-list,.front-company,.front-news-grid,.front-investor-grid,.front-resources{grid-template-columns:1fr;gap:32px}.front-program-intro h3{font-size:32px}.front-program-title{flex-direction:column;gap:12px}.front-program-title h3{font-size:21px}.front-program-list{border-top:1px solid #d3d3d3;padding-top:25px}.front-research-item h3{font-size:24px}.front-company-photo img{aspect-ratio:1.25}.front-company h2{font-size:33px}.front-news-feature h3{font-size:27px}.front-news-list h3{font-size:21px}.front-resources{padding:35px 4.5%}.investor-company-context{padding:23px}}@media (min-width:1700px){.research-hero,.research-chapter{padding-left:max(4.5%,50vw - 775px);padding-right:max(4.5%,50vw - 775px)}}@media (max-width:1050px){.research-hero{gap:4%}.research-hero h1{font-size:43px}.molecule-composition{padding:24px 22px}.composition-components>div{min-height:140px;padding:16px 12px}.composition-components strong{font-size:30px}.research-nav a{gap:8px;padding:19px 10px;font-size:12px}.chapter-heading{column-gap:5%}.foundation-grid,.clinical-tracks,.platform-pillars{gap:25px}.clinical-study-copy,.clinical-study-result{padding:28px}.pipeline-controls{flex-direction:column;align-items:flex-start;gap:0}.research-page .pipeline-legend{flex-direction:column;gap:12px}.pipeline-collection>header{gap:30px;padding:22px}.research-page .pipeline-row,.research-page .pipeline-labels{gap:25px;padding-left:22px;padding-right:22px}.research-library{column-gap:40px}.resource-overview h2,.resource-section-heading h2,.resource-document-intro h2{font-size:34px}.resource-sources{grid-template-columns:1fr;gap:5px}.resource-sources span{margin-bottom:10px}}@media (max-width:760px){.site-header{min-height:90px}.research-hero{grid-template-columns:1fr;gap:42px;padding-top:44px;padding-bottom:40px}.research-hero h1{font-size:clamp(38px,7.5vw,57px)}.research-hero-copy>.eyebrow{margin-bottom:26px}.research-hero-copy>p:not(.eyebrow){font-size:16px}.research-hero-actions{gap:22px;margin-top:24px;font-size:13px}.molecule-composition{padding:25px 24px}.composition-components{padding-top:30px}.composition-components>div{min-height:130px;padding:16px}.composition-components strong{font-size:clamp(26px,6.5vw,40px)}.composition-result>span{font-size:28px}.research-nav{grid-template-columns:repeat(3,minmax(0,1fr))}.research-nav a{min-height:44px;padding:8px 10px;line-height:1.4}.research-nav a:nth-child(-n+3){border-bottom:1px solid #d3d3d3}.research-nav a:nth-child(3){border-right:0}.research-nav a span{display:none}.chapter-heading{margin-bottom:32px;display:block}.chapter-heading h2{font-size:34px}.chapter-heading>p:last-child:not(.eyebrow){margin-top:22px;font-size:15px}.foundation-grid,.clinical-tracks,.platform-pillars{grid-template-columns:1fr;gap:28px}.foundation-grid article{border-top-width:1px}.foundation-grid h3{margin-top:16px;font-size:23px}.foundation-grid p{font-size:14px}.research-citation{flex-direction:column;gap:14px}.clinical-feature{grid-template-columns:1fr}.clinical-study-copy{padding:26px 23px}.clinical-study-copy h3{margin-top:25px;font-size:29px}.clinical-study-result{padding:28px 23px}.clinical-study-note{padding:20px 23px}.clinical-tracks{margin-top:32px}.clinical-tracks h3{margin-top:15px}.research-page .filter-tabs{gap:7px}.research-page .filter-tabs button{padding:11px 13px;font-size:12px}.results-count{margin:14px 0 0}.pipeline-collection{margin-top:24px}.pipeline-collection>header{padding:23px;display:block}.pipeline-collection>header h3{font-size:25px}.pipeline-collection>header p{margin-top:17px;font-size:13px}.research-page .pipeline-labels{display:none}.research-page .pipeline-row{grid-template-columns:1fr 1fr;gap:16px 22px;padding:23px 18px}.research-page .pipeline-row.marketed{padding-left:14px}.research-page .pipeline-row>div:last-child{border-top:1px solid #d3d3d3;grid-column:1/-1;padding-top:14px}.pipeline-row h4{font-size:15px}.platform-pillars h3{margin-top:18px}.platform-operations{grid-template-columns:1fr;gap:28px;margin-top:35px;padding-top:34px}.platform-operations h3{font-size:29px}.research-library{grid-template-columns:1fr}.research-paper{padding-bottom:5px}.research-paper h3{font-size:26px}.research-next{margin-bottom:45px;padding:28px 24px;display:block}.research-next h2{font-size:32px}.research-next>a{margin-top:32px;font-size:13px}.resource-heading{padding-top:45px;padding-bottom:30px}.resource-heading h1{font-size:65px}.resource-heading .resource-generic{font-size:21px}.resource-nav{grid-template-columns:repeat(2,minmax(0,1fr));gap:0 18px;padding:8px 0;display:grid}.resource-nav a{align-items:center;min-height:44px;padding:7px 0;display:flex}.medicine-details.resource-overview{grid-template-columns:1fr;gap:30px;padding-top:45px}.resource-overview h2{font-size:32px}.resource-sources{grid-template-columns:1fr auto;font-size:10px}.resource-pack-hero{padding:20px 0}.resource-pack-hero figcaption{margin-top:28px}.resource-treatment-grid,.resource-presentation-grid,.resource-document,.medicine-resources.resource-guidance{grid-template-columns:1fr;gap:28px}.resource-section-heading h2,.resource-document-intro h2{font-size:32px}.resource-treatment-grid h3{font-size:24px}.resource-presentation figcaption strong{font-size:21px}.resource-document-card{padding:25px}.resource-guidance .resource-section-heading{margin:0}.resource-chapters{grid-template-columns:1fr 1fr}.resource-chapters button{border-bottom:1px solid #d3d3d3}.resource-chapters button:nth-child(2){border-right:0}.resource-safety h2{font-size:32px}}.contact-channels{flex-wrap:wrap;gap:16px 30px;margin-top:28px;font-size:15px;display:flex}.contact-channels a{border-bottom:1px solid var(--ink);color:var(--ink);padding-bottom:7px}.contact-directory{grid-template-columns:repeat(2,minmax(0,1fr));gap:4%}.contact-directory>div,.contact-directory #investor-contact{scroll-margin-top:28px}.contact-directory h2{min-height:2.5em;margin-bottom:18px;font-size:28px}.contact-directory .contact-big{font-size:clamp(20px,1.8vw,26px)}.contact-directory .text-link{margin-top:20px}.news-row-copy{min-width:0}.news-heading{padding-top:34px;padding-bottom:28px}.site .news-heading h1{margin:0 0 14px;font-size:clamp(36px,4vw,52px)}.news-heading>p{margin:0}.news-heading+.news-archive{padding-top:28px}.article-provenance{width:100%}.article-provenance summary{cursor:pointer;color:var(--ink);line-height:1.7}.article-aside .article-provenance p{margin-top:16px}.article-provenance a{text-underline-offset:3px;text-decoration:underline}.article-aside>.article-provenance+p{margin-top:18px}.news-row-copy>p{color:#555;max-width:65ch;margin:10px 0 0;font-size:15px;line-height:1.65}.news-row-copy:lang(zh)>p{line-height:1.8}.detail-heading .article-standfirst{color:#333;max-width:68ch;margin:24px 0 20px;font-size:19px;line-height:1.65}.detail-heading:lang(zh) .article-standfirst{max-width:40em;line-height:1.8}.article-body .context-note h2{margin:0 0 12px;font-size:18px;font-weight:500;line-height:1.45}.article-record-heading{border-bottom:1px solid var(--line);color:var(--ink);flex-wrap:wrap;align-items:baseline;gap:10px 20px;margin:0 0 24px;padding:0 0 14px;display:flex}.article-record-heading h2{margin:0;font-size:16px;font-weight:500;line-height:1.5}.article-record-heading time{color:#666;font-size:13px}@media (max-width:1000px){.contact-directory{grid-template-columns:1fr;gap:40px}.contact-directory>div+div{border-top:1px solid var(--line);padding-top:36px}.contact-directory h2{min-height:0}.contact-directory .contact-big{font-size:clamp(22px,6.8vw,27px)}}@media (max-width:450px){.contact-channels{gap:14px 22px}.news-row-copy>p{font-size:15px}.detail-heading .article-standfirst{margin-top:20px;font-size:17px}}.investors-heading{grid-template-columns:1.05fr 1fr;gap:12px 8%;padding-top:36px;padding-bottom:34px;display:grid}.investors-heading h1{grid-area:1/1/3;margin:0;font-size:50px;line-height:1.1}.investors-heading>p:not(.eyebrow){grid-area:1/2/3;max-width:590px;margin:0;font-size:16px;line-height:1.7}.investor-results-link{flex-wrap:wrap;grid-column:2;gap:12px 24px;margin:5px 0 0;display:flex}.investor-results-link a:first-child{font-size:16px}.investor-report-results{border-top:1px solid var(--line);grid-column:2;margin-top:12px;padding-top:18px}.site .investor-report-results h2{letter-spacing:-.015em;margin:0 0 9px;font-size:20px;font-weight:500;line-height:1.4}.site .investor-report-results p{color:var(--muted);margin:0;font-size:13px;line-height:1.6}.investor-report-results .document-editions{flex-wrap:wrap;gap:12px 24px;margin-top:14px}.investor-report-results .document-editions a{font-size:13px}.investor-layout{padding-top:0;display:block}.investor-nav{grid-template-columns:repeat(7,minmax(0,1fr));gap:18px;margin-bottom:30px;display:grid;position:static}.investor-nav a{border-top:2px solid var(--line);border-bottom:0;min-height:65px;padding:12px 0;font-size:14px;line-height:1.4;display:block}.investor-nav a[aria-current=page]{border-top-color:var(--ink)}.investor-nav a span{margin-left:6px;display:inline-block}.investor-content{max-width:none;scroll-margin-top:24px}.investor-content>.archive-controls{background:#f5f5f5;margin:0;padding:22px 24px}.investor-content>.archive-controls label,.investor-results-header .plain-button{font-size:13px}.investor-content>.archive-controls input,.investor-content>.archive-controls select{font-size:14px}.investor-results-header{justify-content:space-between;align-items:center;gap:16px;min-height:44px;margin:10px 0;display:flex}.investor-results-header .results-count{margin:0}.investor-results-header .plain-button{white-space:nowrap;min-height:44px}.investor-content .filing-row{grid-template-columns:130px minmax(0,1fr) 280px;align-items:baseline;gap:28px;padding:25px 0;display:grid}.investor-content .filing-row>div:nth-child(2){display:contents}.investor-content .filing-row .filing-title{font-size:18px;line-height:1.45}.investor-content .filing-row .document-editions{flex-wrap:wrap;justify-content:flex-end;gap:12px 20px;margin:0}.investor-content .filing-row .document-editions a{font-size:13px}.investor-content .filing-row .source-note{grid-column:2/-1}@media (max-width:760px){.investors-heading{padding-top:30px;padding-bottom:28px;display:block}.investors-heading h1{margin:0 0 18px;font-size:36px}.investors-heading>p:not(.eyebrow){font-size:16px}.investor-results-link{gap:12px 16px;margin-top:18px}.investor-report-results{margin-top:22px}.investor-layout{padding-top:16px}.investor-nav{grid-template-columns:1fr 1fr;gap:0 22px;margin-bottom:24px}.investor-nav a{min-height:0;padding:12px 0;font-size:14px}.investor-content>.archive-controls{gap:12px;padding:20px 14px}.investor-content>.archive-controls label:first-child{flex:1;min-width:125px}.investor-content>.archive-controls input{width:100%}.investor-content .filing-row{padding:23px 0;display:block}.investor-content .filing-row .filing-title{margin:12px 0;font-size:17px;display:block}.investor-content .filing-row .document-editions{justify-content:flex-start;margin-top:18px}}.investor-nav a{justify-content:space-between;align-items:baseline;gap:8px;display:flex}.investor-nav a span{flex:none;margin-left:0}@media (min-width:761px) and (max-width:1100px){.investors-heading h1{font-size:clamp(36px,4.7vw,50px)}.investor-nav{grid-template-columns:repeat(4,minmax(0,1fr));gap:10px 22px}.investor-content .filing-row{grid-template-columns:95px minmax(0,1fr) 195px;gap:22px}}.investors-heading>*{min-width:0}.investor-nav a>span:first-child{min-width:0;font-size:inherit;flex:1}.investor-nav a>span:last-child{flex:none}.investor-content .filing-row .source-note{margin:0}@media (max-width:760px){.investors-heading h1{overflow-wrap:break-word;font-size:clamp(31px,9.2vw,36px)}.investor-content .filing-row .source-note{margin-top:14px}}.investors-heading:lang(zh) h1{letter-spacing:0;font-size:46px;line-height:1.2}.investors-heading:lang(zh)>p:not(.eyebrow){line-height:1.8}.investor-content:lang(zh) h2,.investor-content:lang(zh) h3,.investor-content:lang(zh) .filing-title,.investor-company-context:lang(zh) h2{letter-spacing:0}.investor-company-context{grid-template-columns:minmax(0,.8fr) minmax(0,1.2fr);gap:6%;display:grid}.investor-company-context>div:nth-child(2){min-width:0;max-width:760px}.investor-tools .investor-section-picker,.investor-mobile-navigation,.investor-ir-shortcut,.investor-results-label,.investor-results-date,.investor-mobile-introduction,.investor-content>.investor-tools-section-only{display:none}@media (max-width:760px){.investors-heading--overview{padding-bottom:24px;position:relative}.investors-heading--overview h1{margin-bottom:24px}.investor-desktop-introduction,.investor-results-inline-date,.investor-browse-shortcut,.investor-nav{display:none}.investor-ir-shortcut{font-size:13px;display:block;position:absolute;top:30px;right:18px}.investor-results-spotlight{margin-top:0;display:block}.investors-heading .investor-results-label{color:var(--ink);margin:0 0 7px;font-size:12px;font-weight:500;line-height:1.5;display:block}.investor-results-spotlight>a:first-child{font-size:17px;font-weight:500;line-height:1.42;text-decoration:none;display:block}.investor-results-spotlight .investor-results-title{text-underline-offset:3px;text-decoration:underline;text-decoration-thickness:1px}.investor-results-date{color:#666;margin-top:8px;font-size:12px;display:block}.investor-layout{padding-top:22px}.investor-content>.archive-controls.investor-tools{background:0 0;grid-template-columns:minmax(0,1fr) 88px;gap:15px 16px;margin:0;padding:0;display:grid}.investor-tools label,.investor-tools .investor-section-picker,.investor-mobile-navigation .investor-section-picker{gap:7px;min-width:0;margin:0;font-size:12px;display:grid}.investor-content>.investor-tools label:first-child{min-width:0}.investor-tools .investor-section-picker{grid-area:1/1}.investor-tools .investor-year-control{grid-area:1/2}.investor-tools .investor-search-control{grid-area:2/1/auto/-1}.investor-content>.investor-tools-section-only .investor-section-picker{grid-column:1/-1}.investor-tools select,.investor-tools input,.investor-mobile-navigation select{background:0 0;border:1px solid #aab4bb;border-radius:0;width:100%;min-width:0;max-width:100%;min-height:44px;margin:0;padding-inline:12px;font-size:14px}.investor-mobile-navigation{margin-bottom:24px;display:block}.investor-results-header{margin-top:20px}.investor-mobile-introduction{margin-top:22px;display:block}}@media (min-width:541px) and (max-width:760px){.investor-ir-shortcut{right:32px}.investor-content>.archive-controls.investor-tools{grid-template-columns:minmax(0,1fr) 104px minmax(0,1.35fr);align-items:end}.investor-tools .investor-search-control{grid-area:1/3}}.investor-company-context h2{font-size:28px;line-height:1.25}.investor-company-context .company-local-nav{flex-wrap:wrap;gap:12px 22px;margin-inline:0}@media (max-width:760px){.investors-heading:lang(zh) h1{font-size:34px}.investor-company-context{grid-template-columns:minmax(0,1fr);gap:18px}.investor-company-context h2{font-size:25px}}#pipeline .pipeline-overview-heading{justify-content:space-between;align-items:baseline;gap:24px;margin-bottom:24px;display:flex}#pipeline .pipeline-overview-heading h2{letter-spacing:-.025em;color:#1f4e79;align-items:baseline;gap:20px;margin:0;font-size:32px;font-weight:600;line-height:1.2;display:flex}#pipeline .pipeline-overview-heading h2 span{color:#666;letter-spacing:0;font-size:13px;font-weight:400}#pipeline .pipeline-overview-heading>a{white-space:nowrap;text-underline-offset:4px;font-size:12px}#pipeline .pipeline-overview-tools{border-bottom:1px solid #d3d3d3;align-items:center;gap:24px;padding-bottom:14px;display:flex}#pipeline .filter-tabs{flex-wrap:wrap;gap:4px 17px;display:flex}#pipeline .filter-tabs button{color:#444;background:#fff;border:0;border-bottom:2px solid #0000;border-radius:0;min-height:44px;padding:10px 0;font-size:13px}#pipeline .filter-tabs button[aria-pressed=true]{color:#1f4e79;border-bottom-color:#35cbf5;font-weight:600}#pipeline .filter-tabs button:hover{color:#1f4e79;border-bottom-color:#1f4e79}#pipeline .results-count{color:#666;flex-shrink:0;margin:0 0 0 auto;font-size:12px}#pipeline .pipeline-filter-select{display:none}#pipeline .pipeline-program-group{margin-top:30px}#pipeline .pipeline-program-group+.pipeline-program-group{margin-top:44px}#pipeline .pipeline-group-heading{grid-template-columns:minmax(0,1fr) minmax(0,1fr);align-items:baseline;gap:30px;padding-bottom:20px;display:grid}#pipeline .pipeline-group-heading h3{letter-spacing:-.025em;color:#1f4e79;margin:0;font-size:24px;font-weight:600;line-height:1.3}#pipeline .pipeline-group-heading h3 span{letter-spacing:0;color:#666;white-space:nowrap;margin-left:22px;font-size:12px;font-weight:400}#pipeline .pipeline-group-heading p{color:#555;max-width:580px;margin:0;font-size:13px;line-height:1.55}#pipeline .pipeline-molecule{border-top:1px solid #d3d3d3;grid-template-columns:180px minmax(0,1fr);gap:24px;padding:22px 0;display:grid}#pipeline .pipeline-molecule-core{border-top:0;padding:0;display:block}#pipeline .pipeline-molecule:not(.pipeline-molecule-core) .pipeline-indication+.pipeline-indication{border-top:1px solid #e0e0e0;margin-top:18px;padding-top:18px}#pipeline .pipeline-molecule-heading h4{color:#1f4e79;margin:0 0 8px;font-size:19px;font-weight:600;line-height:1.3}#pipeline .pipeline-molecule-heading p{color:#666;margin:0;font-size:12px;line-height:1.5}#pipeline .pipeline-molecule-heading .pipeline-target-definition{text-wrap:pretty;margin-top:6px}#pipeline .pipeline-indication{grid-template-columns:minmax(170px,.7fr) minmax(0,2fr);gap:30px;display:grid}#pipeline .pipeline-molecule-core .pipeline-indication{border-top:1px solid #d3d3d3;grid-template-columns:minmax(200px,.72fr) minmax(0,2fr);padding:23px 0}#pipeline .pipeline-indication>h4,#pipeline .pipeline-indication>h5{color:#333;letter-spacing:0;margin:0;font-size:16px;font-weight:600;line-height:1.5}#pipeline .pipeline-territory{grid-template-columns:minmax(110px,.7fr) minmax(150px,1fr) minmax(0,1.7fr);align-items:start;column-gap:24px;display:grid}#pipeline .pipeline-territory+.pipeline-territory{border-top:1px solid #e0e0e0;margin-top:20px;padding-top:20px}#pipeline .pipeline-territory-location p{color:#333;margin:0;font-size:14px;line-height:1.5}#pipeline .pipeline-status{color:#1f4e79;font-size:14px;font-weight:500;line-height:1.45;display:inline}#pipeline .pipeline-status-marketed{border-left:3px solid #35cbf5;padding-left:8px;font-weight:600}#pipeline .pipeline-status-scope{color:#666;margin:8px 0 0;font-size:13px;line-height:1.65}#pipeline .pipeline-territory-detail>p{color:#444;margin:0;font-size:14px;line-height:1.6}#pipeline .pipeline-territory-detail>p+p{margin-top:9px}#pipeline .pipeline-territory-detail .pipeline-regimen{color:#666;font-size:13px}#pipeline .pipeline-territory-detail .pipeline-status-date{color:#666;margin-top:10px;font-size:13px}#pipeline .pipeline-reading-notes{border-top:1px solid #d3d3d3;grid-template-columns:minmax(200px,.72fr) minmax(0,2fr);gap:30px;margin-top:32px;padding-top:24px;display:grid}#pipeline .pipeline-reading-notes h3{color:#333;margin:0;font-size:17px;font-weight:600;line-height:1.45}#pipeline .pipeline-reading-notes p{color:#555;max-width:850px;margin:0 0 14px;font-size:14px;line-height:1.65}html[lang=zh-CN] #pipeline .pipeline-overview-heading h2,html[lang=zh-CN] #pipeline .pipeline-group-heading h3{letter-spacing:0}html[lang=zh-CN] #pipeline .pipeline-status-scope,html[lang=zh-CN] #pipeline .pipeline-territory-detail .pipeline-regimen{font-size:14px;line-height:1.75}#pipeline .pipeline-reading-notes a{color:#1f4e79;text-underline-offset:3px;text-decoration:underline}:is(#pipeline button:focus-visible,#pipeline select:focus-visible,#pipeline a:focus-visible){outline-offset:4px;outline:3px solid #ff2d16}@media (max-width:1100px){#pipeline .pipeline-overview-tools{flex-wrap:wrap;gap:4px 20px}#pipeline .pipeline-molecule{grid-template-columns:145px minmax(0,1fr);gap:22px}#pipeline .pipeline-molecule .pipeline-indication{display:block}#pipeline .pipeline-indication>h4,#pipeline .pipeline-indication>h5{margin-bottom:16px}#pipeline .pipeline-territory{grid-template-columns:minmax(100px,.75fr) minmax(130px,.9fr) minmax(0,1.6fr);gap:18px}}@media (max-width:760px){#pipeline .pipeline-overview-heading{margin-bottom:20px;display:block}#pipeline .pipeline-overview-heading h2{gap:12px;margin-bottom:11px;font-size:27px}#pipeline .pipeline-overview-heading h2 span,#pipeline .pipeline-overview-heading>a{font-size:11px}#pipeline .pipeline-overview-tools{align-items:flex-end;gap:12px;padding-bottom:16px;display:flex}#pipeline .filter-tabs{display:none}#pipeline .pipeline-filter-select{flex:1;min-width:0;display:block}#pipeline .pipeline-filter-select>span{color:#555;margin-bottom:6px;font-size:12px;display:block}#pipeline .pipeline-filter-select select{width:100%;min-height:44px;font:inherit;color:#1f4e79;background:#fff;border:1px solid #aaa;border-radius:0;padding:8px 26px 8px 10px;font-size:16px}#pipeline .results-count{flex-basis:100%;margin:0;font-size:11px!important}#pipeline .pipeline-program-group{margin-top:23px}#pipeline .pipeline-program-group+.pipeline-program-group{margin-top:35px}#pipeline .pipeline-group-heading{padding-bottom:17px;display:block}#pipeline .pipeline-group-heading h3{letter-spacing:-.02em;font-size:22px}#pipeline .pipeline-group-heading h3 span{margin-left:14px;font-size:11px}#pipeline .pipeline-group-heading p{margin-top:10px;font-size:14px;line-height:1.55}#pipeline .pipeline-molecule{padding:20px 0;display:block}#pipeline .pipeline-molecule-core{padding:0}#pipeline .pipeline-molecule-heading{margin-bottom:17px}#pipeline .pipeline-molecule-heading h4{margin-bottom:4px;font-size:19px}#pipeline .pipeline-molecule-heading p{font-size:12px}#pipeline .pipeline-molecule-core .pipeline-indication{padding:21px 0;display:block}#pipeline .pipeline-indication>h4,#pipeline .pipeline-indication>h5{margin-bottom:16px;font-size:16px;line-height:1.45}#pipeline .pipeline-territory{grid-template-columns:minmax(0,.85fr) minmax(0,1.15fr);gap:11px 20px;display:grid}#pipeline .pipeline-territory-location p,#pipeline .pipeline-status{font-size:13px}#pipeline .pipeline-status-scope{margin-top:6px}#pipeline .pipeline-territory-detail{grid-column:1/-1}#pipeline .pipeline-territory-detail>p{font-size:14px;line-height:1.6}#pipeline .pipeline-territory-detail .pipeline-regimen{font-size:13px}#pipeline .pipeline-territory-detail>a{margin-top:8px}#pipeline .pipeline-territory+.pipeline-territory{margin-top:17px;padding-top:17px}#pipeline .pipeline-reading-notes{margin-top:25px;padding-top:22px;display:block}#pipeline .pipeline-reading-notes h3{margin-bottom:15px;font-size:17px}#pipeline .pipeline-reading-notes p{font-size:14px}}#pipeline{padding-top:48px}@media (max-width:760px){#pipeline{padding-top:32px}#pipeline .pipeline-overview-tools{position:relative}#pipeline .results-count{line-height:1.5;position:absolute;top:0;right:0;font-size:11px!important}#pipeline .pipeline-group-other .pipeline-molecule{grid-template-columns:minmax(100px,.8fr) minmax(0,1.2fr);gap:15px 20px;display:grid}#pipeline .pipeline-group-other .pipeline-molecule-heading{margin:0}#pipeline .pipeline-group-other .pipeline-indications,#pipeline .pipeline-group-other .pipeline-indication{display:contents}#pipeline .pipeline-group-other .pipeline-indication>h5{grid-column:2;margin:0}#pipeline .pipeline-group-other .pipeline-territories{grid-column:1/-1}}.medicine-opening{color:var(--body-text);padding:36px 4.5% 40px}.medicine-opening.is-accepted{grid-template-columns:minmax(0,1fr) minmax(0,1fr);grid-template-areas:"copy pack""actions pack";gap:22px 6%;display:grid}.medicine-opening-copy{grid-area:copy;min-width:0}.medicine-opening .eyebrow{font-size:12px}.medicine-opening h1{letter-spacing:-.035em;color:var(--body-text);margin:20px 0 10px;font-size:clamp(40px,4vw,54px);font-weight:500;line-height:1.08}.medicine-opening .resource-generic{color:var(--ink);margin:0 0 18px;font-size:21px;font-weight:400;line-height:1.4}.medicine-opening-description{max-width:610px;margin:0;font-size:16px;line-height:1.65}.medicine-opening .medicine-opening-identity{max-width:580px;color:var(--body-text);margin:0 0 12px;font-size:18px;line-height:1.6}.medicine-opening .medicine-approval-source{color:#666;flex-wrap:wrap;gap:4px 12px;margin:12px 0 0;font-size:12px;display:flex}.medicine-approval-source a{text-underline-offset:3px;text-decoration:underline}.medicine-opening-pack{grid-area:pack;align-self:center;min-width:0;margin:0;padding-top:18px}.medicine-opening-pack img{width:100%;height:auto;display:block}.medicine-opening-pack figcaption{color:#666;flex-wrap:wrap;justify-content:space-between;align-items:center;gap:4px 16px;margin-top:18px;font-size:12px;display:flex}.medicine-opening-pack figcaption a{color:var(--ink);padding:12px 0}.medicine-opening-actions{border-top:2px solid var(--red);grid-area:actions}.medicine-opening-actions a{min-height:54px;color:var(--body-text);border-bottom:1px solid #d3d3d3;grid-template-columns:minmax(0,1fr) auto;align-items:center;gap:8px 18px;padding:13px 0;font-size:15px;font-weight:500;text-decoration:none;display:grid}.medicine-opening-actions a span:last-child{color:#666;font-size:12px;font-weight:400}.medicine-opening-actions a:hover{color:var(--ink)}.medicine-opening-actions a:hover span:first-child{text-underline-offset:4px;text-decoration:underline}.section.resource-treatment{color:var(--body-text);background:#fff;border-bottom:1px solid #d3d3d3;grid-template-columns:minmax(0,.7fr) minmax(0,1.3fr);gap:20px 6%;margin:0 4.5%;padding:40px 0;display:grid}.resource-treatment .resource-section-heading{margin:0}.resource-treatment h2,.resource-presentations h2,.resource-document-intro h2,.resource-guidance .resource-section-heading h2,.medicine-evidence h2,.resource-safety h2{color:var(--body-text);letter-spacing:-.025em;margin:0 0 14px;font-size:28px;font-weight:500;line-height:1.3}.resource-treatment .resource-section-heading p{margin-bottom:0}.resource-treatment-grid{gap:32px}.resource-treatment-grid article{border-top:0;padding-top:0}.resource-treatment-grid h3{color:var(--body-text);margin:0 0 10px;font-size:18px;font-weight:500}.resource-treatment-grid p{margin:0}.resource-treatment>.source-note{grid-column:2;margin:0;color:#666!important}.section.resource-presentations{padding:40px 4.5%}.resource-presentations .resource-section-heading{margin:0 0 24px}.resource-presentation-grid{gap:6%}.presentation.resource-presentation{gap:16px;padding:18px 0 0}.resource-presentation figcaption{margin-top:auto}.resource-presentation figcaption strong{font-size:21px;font-weight:500}.resource-presentations>.source-note{margin-top:20px}.section.resource-document{gap:6%;padding:40px 4.5%}.resource-document-intro p{max-width:620px}.resource-document-card{background:0 0;border-top:0;border-left:1px solid #d3d3d3;padding:0 0 0 28px}.resource-document-format{justify-content:flex-start;gap:12px}.resource-document-format span:first-child{letter-spacing:0;font-size:14px;font-weight:500}.resource-document-card h3{color:var(--body-text);margin:18px 0;font-size:20px;font-weight:500}.resource-document-meta>div{padding:10px 0}.resource-document-card .primary-button{max-width:100%;display:inline-block}.medicine-resources.resource-guidance{grid-template-columns:minmax(0,.8fr) minmax(0,1.2fr);gap:6%;padding:44px 4.5%}.resource-video-content .label-clarification{border-left-width:2px;padding:18px}.resource-video-content .label-clarification h3{color:var(--body-text);font-size:17px;font-weight:500}.resource-video-content video{margin-top:20px}.resource-chapters button{min-height:70px}.medicine-details.resource-overview.medicine-evidence{border-top:1px solid #d3d3d3;padding:36px 4.5%;display:block}.medicine-evidence .resource-overview-copy{grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:22px 6%;display:grid}.medicine-evidence h2{grid-column:1/-1;margin-bottom:0}.medicine-evidence .resource-source-statement{margin:0}.medicine-evidence .resource-source-statement .eyebrow{font-size:13px}.medicine-evidence .resource-source-statement blockquote{font-size:16px}.medicine-evidence .resource-source-statement>a{font-size:13px}.medicine-evidence .resource-facts{margin:0}.medicine-evidence .resource-sources{grid-column:1/-1;max-width:850px;margin-top:0}.section.resource-safety{color:var(--body-text);border-top:2px solid var(--red);background:#fff;padding:36px 4.5%}.resource-safety .eyebrow{color:#666;margin-bottom:16px;font-size:11px}.resource-safety a{color:var(--ink)}.resource-safety a[href^=tel]{letter-spacing:-.015em;font-size:27px;font-weight:500}.resource-safety>a:last-child{font-size:14px}@media (max-width:760px){.medicine-opening{padding:26px 4.5% 28px}.medicine-opening.is-accepted{grid-template-columns:minmax(0,1fr);grid-template-areas:"copy""pack""actions";gap:16px}.medicine-opening h1{margin:16px 0 8px;font-size:40px}.medicine-opening .resource-generic{margin-bottom:12px;font-size:19px}.medicine-opening-description{font-size:15px;line-height:1.6}.medicine-opening .medicine-opening-identity{margin-bottom:10px;font-size:17px}.medicine-opening .medicine-approval-source{margin-top:10px;font-size:11px}.medicine-opening-pack{padding:0}.medicine-opening-pack figcaption{gap:0 10px;margin-top:8px;font-size:11px}.medicine-opening-pack figcaption a{padding:10px 0}.medicine-opening-actions a{gap:8px;min-height:52px;font-size:14px}.medicine-opening-actions a span:last-child{font-size:11px}.section.resource-treatment{grid-template-columns:minmax(0,1fr);gap:24px;padding:30px 0}.resource-treatment-grid{grid-template-columns:minmax(0,1fr);gap:22px}.resource-treatment>.source-note{grid-column:1}.resource-treatment h2,.resource-presentations h2,.resource-document-intro h2,.resource-guidance .resource-section-heading h2,.medicine-evidence h2,.resource-safety h2{font-size:25px}.section.resource-presentations,.section.resource-document{padding:30px 4.5%}.resource-document{gap:22px}.resource-document-card{border-top:1px solid #d3d3d3;border-left:0;padding:22px 0 0}.medicine-resources.resource-guidance{grid-template-columns:minmax(0,1fr);gap:22px;padding:32px 4.5%}.medicine-details.resource-overview.medicine-evidence{padding:30px 4.5%}.medicine-evidence .resource-overview-copy{grid-template-columns:minmax(0,1fr);gap:22px}.medicine-evidence .resource-sources{grid-template-columns:minmax(0,1fr);gap:6px;font-size:12px}.medicine-evidence .resource-sources span{margin-bottom:8px}.section.resource-safety{padding:30px 4.5%}}.professional-dialog #professional-title:focus{outline:none}.professional-dialog .dialog-safety{grid-template-columns:minmax(0,1fr) auto;align-items:center;gap:16px;min-height:48px;padding-block:18px 2px;font-size:16px;font-weight:500;line-height:1.5;display:grid}.professional-dialog .dialog-safety>span:first-child{text-underline-offset:4px;text-decoration:underline}.professional-dialog .dialog-safety>span:last-child{font-size:20px}.home-page{color:#333;max-width:none;margin:0}.home-page h1,.home-page h2,.home-page h3{font-family:var(--sans);color:var(--ink);font-weight:500}.home-page:lang(zh-CN) h2,.home-page:lang(zh-CN) h3{letter-spacing:-.015em;line-height:1.35}.home-page p{line-height:1.65}.home-page img{width:100%;height:auto;display:block}.home-page a:hover{text-underline-offset:5px;text-decoration:underline}.home-page .home-label{letter-spacing:.035em;color:var(--ink);margin:0 0 25px;font-size:12px;font-weight:600;line-height:1.4}.home-page time{font-variant-numeric:tabular-nums}.home-action,.home-text-link{color:var(--ink);border-bottom:1px solid;justify-content:space-between;align-items:center;gap:28px;min-height:44px;padding:7px 0;font-size:14px;display:inline-flex}.home-action>span,.home-text-link>span{font-size:22px;line-height:1;transition:transform .18s}.home-action:hover>span,.home-text-link:hover>span{transform:translate(4px)}.home-source{text-underline-offset:4px;font-size:12px;line-height:1.5;text-decoration:underline}.home-opening{color:#333;isolation:isolate;background:0 0;grid-template-columns:minmax(0,1fr);align-items:center;gap:0;padding:0 4.5%;display:grid;position:relative;overflow:hidden}.home-introduction{flex-direction:column;justify-content:flex-start;align-items:flex-start;gap:0;width:64%;min-height:570px;padding:40px 0 36px;display:flex}.home-introduction .home-label{z-index:1;color:var(--ink);letter-spacing:.035em;justify-content:flex-start;gap:24px;margin:0 0 21px;font-size:13px;display:flex;position:relative}.home-introduction .home-label>span{font-size:11px;font-weight:400}.home-introduction h1{z-index:1;letter-spacing:-.042em;white-space:pre-line;text-wrap:pretty;max-width:790px;color:var(--ink);margin:0 0 28px;font-size:clamp(52px,12.5vw - 82px,68px);line-height:1.035;position:relative}.home-intro-aside{z-index:1;align-self:flex-start;width:440px;max-width:100%;padding-bottom:5px;position:relative}.home-page .home-intro-text{color:#333;max-width:100%;margin-bottom:24px;font-size:18px;line-height:1.65}.home-introduction .home-action{border:1px solid var(--ink);min-width:180px;color:var(--ink);gap:30px;padding:12px 18px;font-size:15px;line-height:1.6}.home-introduction .home-action:hover{background:var(--ink);color:#fff}.home-protein-art{z-index:0;flex-direction:column;justify-content:flex-start;width:810px;min-width:0;height:585px;margin:0;padding:0;display:flex;position:absolute;top:-36px;right:-90px}.home-protein-art img{object-fit:contain;width:100%;height:610px;margin:0}.home-protein-art figcaption{color:#666;justify-content:space-between;gap:15px;width:430px;max-width:none;margin:0;padding:0;font-size:12px;line-height:1.6;display:flex;position:absolute;bottom:0;right:155px}.home-protein-art figcaption a{color:var(--ink);white-space:nowrap}.home-corporate-context{z-index:1;color:#333;border-top:1px solid #ccc;border-bottom:1px solid #ccc;grid-column:1/-1;grid-template-columns:1fr 1.2fr auto;align-items:center;gap:30px;padding:20px 0;display:grid;position:relative}.home-corporate-context p{margin:0;font-size:14px;line-height:1.55}.home-corporate-context p:first-child{color:var(--ink);font-weight:500}.home-corporate-context a{max-width:190px;color:var(--ink);align-items:center;gap:16px;font-size:14px;line-height:1.55;display:flex}.home-section{padding:58px 4.5%}.home-section-heading{grid-template-columns:1fr auto;align-items:end;gap:0 35px;margin-bottom:32px;display:grid}.home-section-heading .home-label{letter-spacing:0;color:#666;grid-column:1/-1;margin-bottom:8px;font-size:13px;font-weight:400}.home-section-heading h2{color:var(--ink);letter-spacing:-.015em;white-space:pre-line;margin:0;font-size:24px;font-weight:400;line-height:1.3}.home-section-heading>a{margin-bottom:5px;font-size:13px}.home-development{background:#fff}.home-medicine-portrait{color:#333;background:#fff;border:0;border-bottom:1px solid #ccc;grid-template-columns:1.1fr 1fr;align-items:center;gap:64px;margin:0 0 32px;padding:15px 0 28px;display:grid;position:relative}.home-medicine-image{margin-left:-12px;padding:0}.home-portrait-caption{padding:15px 0 15px 25px}.home-page .home-portrait-caption>.home-first-medicine{color:var(--ink);margin-bottom:12px;font-size:17px;font-weight:400}.home-portrait-caption h3{color:var(--ink);letter-spacing:-.025em;margin-bottom:12px;font-size:38px;line-height:1.15}.home-portrait-caption>p{color:#333}.home-page .home-portrait-caption>p{font-size:16px;line-height:1.65}.home-portrait-caption>p:not(.home-first-medicine){margin:0 0 16px}.home-portrait-caption p.home-approved-scope{color:#666;max-width:430px}.home-portrait-caption .home-action{min-width:190px;font-size:13px}.home-development-browser{grid-template-columns:.85fr 1.5fr;align-items:start;gap:28px 45px;display:grid}.home-development-workspace{grid-area:1/2/span 2;min-width:0}.home-development-select>p:first-child{color:#333;max-width:370px;margin:0 0 25px;font-size:16px;line-height:1.8}.home-view-buttons{border-bottom:1px solid var(--ink);grid-template-columns:minmax(0,1fr) minmax(0,1.5fr);gap:0;display:grid}.home-view-buttons button{cursor:pointer;color:var(--ink);text-align:left;background:0 0;border:0;align-items:center;min-height:56px;padding:14px 22px;font-size:15px;font-weight:500;line-height:1.45;transition:background-color .16s,color .16s;display:flex}.home-view-buttons button[aria-pressed=true]{background:var(--ink);color:var(--paper)}.home-view-buttons button[aria-pressed=false]:hover{background:var(--canvas);text-underline-offset:4px;text-decoration:underline}.home-page .home-program-source{color:#666;margin:22px 0 0;font-size:12px}.home-program-view{background:var(--canvas);border-bottom:1px solid #ccc;min-height:365px;padding:24px}.home-page .home-program-state{color:var(--ink);margin:0 0 20px;font-size:13px;font-weight:600}.home-approved-program>h3{letter-spacing:-.025em;margin:0 0 15px;font-size:30px}.home-approved-program>p:not(.home-program-state){margin:0;font-size:14px}.home-approved-program dl{margin:25px 0}.home-approved-program dl>div{border-top:1px solid #ccc;grid-template-columns:1fr 1.5fr;gap:20px;padding:15px 0;font-size:13px;display:grid}.home-approved-program dt{color:var(--ink)}.home-approved-program dd{flex-wrap:wrap;gap:8px 25px;margin:0;display:flex}.home-approved-program dd>span{white-space:nowrap}.home-research-programs article{border-bottom:1px solid #ccc;grid-template-columns:1fr 1fr;gap:30px;margin-bottom:21px;padding:8px 0 24px;display:grid}.home-research-programs h3{letter-spacing:-.025em;margin:0 0 14px;font-size:23px;line-height:1.2}.home-research-programs p:not(.home-program-state){margin:0;font-size:14px}.home-research-programs article>div>p{color:#666;font-size:13px}.home-science-entry{background:0 0;border-top:1px solid #ccc;grid-area:2/1;margin-top:0;padding:24px 0 0;display:block}.home-science-entry .home-label{margin-bottom:12px;font-size:11px}.home-science-entry h3{color:var(--ink);letter-spacing:-.025em;margin:0;font-size:24px;line-height:1.3}.home-science-entry>p{max-width:410px;margin:16px 0;font-size:14px}.home-science-entry>a{font-size:14px}.home-company{color:#333;background:0 0;border-top:1px solid #ccc;border-bottom:1px solid #ccc;grid-template-columns:.85fr 1.3fr;align-items:start;gap:28px 7%;padding:58px 4.5%;display:grid}.home-company-copy{grid-area:1/1;padding-top:5px}.home-company-copy h2{color:var(--ink);white-space:pre-line;letter-spacing:-.025em;margin-bottom:24px;font-size:36px;line-height:1.1}.home-company-copy>p:not(.home-label){color:#333;max-width:430px;margin-bottom:20px;font-size:17px}.home-company-photo{grid-area:1/2;margin:0}.home-company-photo img{aspect-ratio:3/2;object-fit:cover}.home-company-photo figcaption{color:var(--ink);flex-wrap:wrap;justify-content:space-between;gap:10px 20px;margin-top:12px;padding:0;font-size:12px;line-height:1.5;display:flex}.home-company-photo figcaption a{text-underline-offset:3px;text-decoration:underline}.home-history{grid-area:2/1/auto/-1;margin-top:8px}.home-history-heading{justify-content:space-between;align-items:baseline;gap:20px;margin-bottom:20px;display:flex}.home-history-heading h3{margin:0;font-size:20px}.home-history-heading .home-text-link{font-size:13px}.home-history ol{grid-template-columns:repeat(3,minmax(0,1fr));gap:36px;margin:0;padding:0;list-style:none;display:grid}.home-history li{border-top:1px solid #ccc;padding-top:20px}.home-history .home-history-year{font-variant-numeric:tabular-nums;letter-spacing:-.025em;color:var(--ink);margin:0 0 12px;font-size:26px;line-height:1.2}.home-history li>p:last-child{max-width:34em;margin:0;font-size:15px}.home-commercial-record{color:#333;border-top:1px solid #ccc;grid-area:3/1/auto/-1;grid-template-columns:.85fr 1.3fr;align-items:start;gap:7%;margin-top:0;padding-top:24px;display:grid}.home-commercial-record>div:first-child{flex-wrap:wrap;align-items:center;gap:8px 20px;display:flex}.home-commercial-record strong{white-space:nowrap;letter-spacing:-.055em;color:var(--ink);flex-shrink:0;font-size:60px;font-weight:400;line-height:1}.home-commercial-record strong>span{vertical-align:top;margin-left:6px;font-size:.7em;line-height:1.2}.home-commercial-record>div:first-child>p{max-width:18em;color:var(--ink);flex:160px;margin:0;font-size:14px}.home-commercial-record>div:last-child{margin-top:0}.home-commercial-record>div:last-child>p{margin:0 0 16px;font-size:14px}.home-news{background:0 0;padding-top:66px;padding-bottom:70px}.home-news-layout{grid-template-columns:minmax(0,2fr) minmax(0,1fr);align-items:start;gap:6.5%;display:grid}.home-news-meta,.home-news-list time{color:#666;font-size:13px}.home-news-meta{flex-wrap:wrap;align-items:baseline;gap:6px 20px;margin:0;display:flex}.home-news-meta>span{color:var(--ink);font-weight:500}.home-feature-heading h3{color:var(--ink);letter-spacing:-.025em;text-wrap:balance;-webkit-hyphens:none;hyphens:none;margin:17px 0 28px;font-size:38px;line-height:1.18}.home-feature-copy p{max-width:64ch;margin:0 0 22px;font-size:17px}.home-feature-actions{flex-wrap:wrap;align-items:baseline;gap:18px 28px;display:flex}.home-feature-actions .home-source{margin:0;font-size:12px}.home-perspective{border-top:1px solid #ccc;grid-template-columns:minmax(0,220px) minmax(0,1fr);align-items:start;gap:24px;margin-top:34px;padding-top:28px;display:grid}.home-perspective-image img{aspect-ratio:2.1;object-fit:cover;object-position:50% 72%;width:100%;height:auto;display:block}.home-page .home-perspective h3{color:var(--ink);letter-spacing:-.015em;text-wrap:pretty;margin:10px 0 0;font-size:22px;font-weight:400;line-height:1.35}.home-perspective h3 span{white-space:nowrap}.home-news-list{border-left:1px solid #ccc;padding-left:32px}.home-news-list article{border-top:1px solid #ccc;padding:22px 0}.home-news-list article:first-child{border-top:0;padding-top:0}.home-news-list article:last-child{padding-bottom:0}.home-page .home-news-list h3{color:var(--ink);letter-spacing:-.015em;margin:10px 0 0;font-size:20px;font-weight:400;line-height:1.4}.home-news-list h3 a{justify-content:space-between;gap:18px;display:flex}.home-news-list h3 span{flex:none;font-size:18px}.home-page .home-investors{background:var(--ink);color:#fff;grid-template-columns:minmax(0,.85fr) minmax(0,1.3fr);align-items:start;gap:7%;padding:58px 4.5% 62px;display:grid}.home-investor-heading .home-label{color:#fff;margin:0 0 23px;font-size:12px}.home-page .home-investor-heading h2{color:#fff;letter-spacing:-.025em;margin:0 0 24px;font-size:35px;font-weight:400;line-height:1.15}.home-investor-heading a{color:#fff;max-width:100%;font-size:13px}.home-report-strip{min-width:0;padding:0}.home-page .home-investors .home-report-strip>p{align-items:baseline;gap:26px;margin:0 0 23px;font-size:12px;display:flex}.home-report-strip time{font-size:12px}.home-page .home-report-strip h3{color:#fff;letter-spacing:-.02em;margin:0;font-size:30px;font-weight:400;line-height:1.25}.home-report-period{letter-spacing:0;margin-top:13px;font-size:14px;line-height:1.5;display:block}.home-report-strip>div{gap:35px;margin-top:27px;display:flex}.home-report-strip a{color:#fff;border-bottom:1px solid var(--cyan);justify-content:space-between;align-items:center;gap:25px;min-width:130px;min-height:44px;padding:10px 0;font-size:14px;display:flex}.home-report-strip a>span{white-space:nowrap;font-size:11px}.home-investors a:focus-visible{outline-color:#fff}html[lang=zh-CN] .home-page .home-introduction h1{letter-spacing:0;font-size:64px;line-height:1.16}html[lang=zh-CN] .home-page .home-intro-text{letter-spacing:0;text-wrap:pretty;line-height:1.8}html[lang=zh-CN] .home-page .home-introduction .home-label{letter-spacing:0}html[lang=zh-CN] .home-page .home-section-heading h2{letter-spacing:0;line-height:1.3}html[lang=zh-CN] .home-page .home-section-heading .home-label{letter-spacing:0}html[lang=zh-CN] .home-page .home-company h2{letter-spacing:0;font-size:34px;line-height:1.35}html[lang=zh-CN] .home-page .home-label{letter-spacing:.025em}html[lang=zh-CN] .home-page .home-portrait-caption h3{letter-spacing:0;font-size:36px;line-height:1.3}html[lang=zh-CN] .home-page .home-feature-heading h3{letter-spacing:0;font-size:34px;line-height:1.35}@media (max-width:1050px){.home-page .home-intro-text{font-size:17px}.home-corporate-context{grid-template-columns:1fr 1fr}.home-corporate-context a{grid-column:2}.home-medicine-portrait{gap:34px}.home-portrait-caption{padding-left:0}.home-news-layout{grid-template-columns:minmax(0,1.7fr) minmax(0,1fr);gap:5%}.home-feature-heading h3{font-size:31px}.home-perspective{grid-template-columns:minmax(0,160px) minmax(0,1fr);gap:20px}.home-page .home-perspective h3{font-size:20px}.home-news-list{padding-left:24px}.home-page .home-news-list h3{font-size:18px}.home-page .home-investors{grid-template-columns:minmax(0,1fr) minmax(0,1.35fr);gap:5%}.home-page .home-investor-heading h2{font-size:29px}.home-page .home-report-strip h3{font-size:27px}}@media (min-width:701px) and (max-width:900px){.home-news-layout{display:block}.home-news-list{border-top:1px solid #ccc;border-left:0;margin-top:34px;padding-left:0}.home-news-list article,.home-news-list article:first-child{grid-template-columns:90px minmax(0,1fr);align-items:baseline;gap:24px;padding:21px 0;display:grid}.home-page .home-news-list h3{margin:0;font-size:20px}.home-news-list article:last-child{padding-bottom:0}}@media (min-width:761px) and (max-width:1050px){.home-introduction{width:54%;min-height:510px;padding-top:34px}.home-introduction h1{font-size:42px;line-height:1.1}html[lang=zh-CN] .home-page .home-introduction h1{font-size:42px;line-height:1.2}.home-intro-aside{width:325px}.home-protein-art{width:480px;height:455px;top:20px;right:-70px}.home-protein-art img{width:480px;height:480px}.home-protein-art figcaption{width:310px;font-size:11px;right:100px}}@media (max-width:760px){.home-opening{padding:26px 22px 0}.home-introduction{display:contents}.home-introduction .home-label{justify-content:space-between;width:100%;margin-bottom:18px;font-size:12px}.home-introduction h1{letter-spacing:-.038em;width:100%;max-width:none;margin:0;font-size:clamp(34px,10.77vw,42px);line-height:1.075}.home-intro-aside{width:100%;padding-bottom:30px}.home-page .home-intro-text{margin-bottom:19px;font-size:16px}.home-introduction .home-action{padding:10px 15px}.home-protein-art{width:calc(100% + 44px);height:calc(100vw - 36px);min-height:314px;max-height:364px;margin:0 -22px 23px;position:relative;top:auto;right:auto}.home-protein-art img{width:min(100vw,420px);height:min(100vw,420px);position:absolute;top:-33px;right:-35px}.home-protein-art figcaption{flex-direction:column;align-items:flex-start;gap:0;width:calc(100% - 44px);font-size:11px;right:22px}.home-protein-art figcaption a{align-items:center;min-height:36px;font-size:12px;display:inline-flex}.home-corporate-context{padding:22px 0;display:block}.home-corporate-context p{margin-bottom:13px;font-size:13px}.home-corporate-context a{max-width:none;margin-top:4px;font-size:13px;display:inline-flex}.home-section{padding:42px 22px}.home-section-heading{margin-bottom:26px}.home-section-heading h2{font-size:22px}.home-medicine-portrait{flex-direction:column;gap:22px;padding:0 0 28px;display:flex}.home-medicine-image{width:100%}.home-portrait-caption{width:100%;padding:0}.home-portrait-caption h3{font-size:32px}.home-page .home-portrait-caption>p{font-size:15px}.home-development-browser{display:block}.home-development-select>p:first-child{font-size:15px}.home-development-workspace{margin-top:28px}.home-program-view{margin-top:0}.home-science-entry{margin-top:31px;padding-top:28px}.home-science-entry h3{font-size:25px}.home-company{padding:42px 22px}.home-company-copy h2{font-size:29px}.home-company-copy>p:not(.home-label){font-size:16px}.home-company-photo figcaption{font-size:11px}html[lang=zh-CN] .home-page .home-introduction h1{font-size:clamp(34px,10.77vw,42px);line-height:1.15}html[lang=zh-CN] .home-page .home-intro-text{line-height:1.85}html[lang=zh-CN] .home-page .home-company h2{font-size:28px}html[lang=zh-CN] .home-page .home-portrait-caption h3{font-size:30px}.home-feature-heading h3{font-size:28px;line-height:1.2}html[lang=zh-CN] .home-page .home-feature-heading h3{font-size:28px}}@media (max-width:700px){.home-introduction .home-label>span{font-size:10px}.home-medicine-image{margin:0 -4px 26px}.home-portrait-caption .home-action{min-width:165px;font-size:12px}.home-section-heading{display:block}.home-section-heading>a{margin-top:12px;font-size:12px}.home-development-select>p:first-child{max-width:none;margin-bottom:20px}.home-view-buttons{gap:0}.home-view-buttons button{align-items:center;padding:12px 14px;font-size:14px}.home-page .home-program-source{margin:16px 0 0;font-size:12px}.home-program-view{min-height:0;padding:22px 18px}.home-page .home-program-state{margin-bottom:15px;font-size:13px}.home-approved-program>h3{font-size:27px}.home-approved-program>p:not(.home-program-state){font-size:14px}.home-approved-program dl>div{grid-template-columns:1fr;gap:10px}.home-approved-program dd{gap:7px 22px;font-size:12px}.home-research-programs article{margin-bottom:20px;padding:5px 0 22px;display:block}.home-research-programs h3{margin-bottom:10px;font-size:23px}.home-research-programs article>p{font-size:14px;margin-top:12px!important}.home-program-view .home-text-link{font-size:14px}.home-science-entry{padding:28px 0 0;display:block}.home-science-entry>p{margin-top:18px;font-size:14px}.home-science-entry>a{margin-top:13px;font-size:14px}.home-company{flex-direction:column;gap:24px;display:flex}.home-company-copy h2{margin-bottom:22px}.home-company-copy>p:not(.home-label){margin-bottom:18px}.home-company-copy>a{font-size:12px}.home-company-photo{width:100%}.home-history{width:100%;margin-top:8px}.home-history-heading{margin-bottom:8px;display:block}.home-history-heading .home-text-link{margin-top:7px;font-size:12px}.home-history ol{display:block}.home-history li{grid-template-columns:105px minmax(0,1fr);gap:15px;padding:20px 0;display:grid}.home-history .home-history-year{margin:0;font-size:17px;line-height:1.65}.home-history li>p:last-child{font-size:14px}.home-commercial-record{padding-top:20px;display:block}.home-commercial-record>div:last-child{margin-top:18px}.home-commercial-record strong{font-size:44px}.home-commercial-record>div:last-child>p{font-size:15px}.home-source{font-size:11px}.home-news{padding-top:44px;padding-bottom:46px}.home-news-layout{display:block}.home-feature-heading h3{margin:13px 0 24px}.home-feature-copy p{font-size:16px}.home-news-list{border-top:1px solid #ccc;border-left:0;margin-top:32px;padding-left:0}.home-news-list article,.home-news-list article:first-child{padding:22px 0}.home-news-list article:last-child{padding-bottom:0}.home-page .home-news-list h3{font-size:20px}.home-page .home-investors{padding:38px 22px 42px;display:block}.home-investor-heading{padding:0 0 30px}.home-investor-heading .home-label{margin-bottom:16px}.home-page .home-investor-heading h2{margin-bottom:14px;font-size:29px}.home-investor-heading>a{font-size:12px}.home-report-strip{border-top:1px solid #fff;padding-top:28px}.home-page .home-investors .home-report-strip>p{justify-content:space-between;margin-bottom:16px}.home-page .home-report-strip h3{font-size:26px}.home-report-period{font-size:13px}.home-report-strip>div{gap:25px;margin-top:20px}.home-report-strip a{flex:1 1 0;gap:12px;min-width:0;font-size:13px}}@media (max-width:550px){.home-perspective{grid-template-columns:minmax(0,1fr);gap:18px}.home-perspective-image img{aspect-ratio:2.55}}@media (max-width:360px){.home-page:lang(en) .home-protein-art{margin-top:4px}}@media (prefers-reduced-motion:reduce){.home-page a>span,.home-perspective-image img,.home-introduction .home-action,.home-view-buttons button{transition:none}.home-action:hover>span,.home-text-link:hover>span,.home-perspective-image:hover img{transform:none}}.science-opening{grid-template-columns:minmax(0,1fr) minmax(0,1.05fr);align-items:center;gap:4%;padding:24px 4.5% 32px;scroll-margin-top:78px;display:grid}.science-opening-copy{max-width:580px;padding-block:36px}.science-page-label{color:var(--ink);margin:0 0 28px;font-size:15px;font-weight:500}.science-opening h1{letter-spacing:-.035em;text-wrap:balance;margin:0 0 29px;font-size:clamp(36px,4.1vw,60px);font-weight:400;line-height:1.09}.research-page .science-opening-rationale{max-width:480px;margin:0;font-size:18px;line-height:1.7}.science-opening-actions{flex-wrap:wrap;gap:12px 28px;margin-top:30px;display:flex}.science-opening-actions a{min-height:44px;color:var(--ink);align-items:center;gap:16px;font-size:15px;font-weight:500;display:inline-flex}.science-opening-actions a:hover{text-underline-offset:5px;text-decoration:underline}.science-fc-figure{min-width:0;margin:0}.science-fc-figure>img{object-fit:contain;width:100%;height:min(39vw,545px);display:block}.science-fc-figure figcaption{color:#666;grid-template-columns:1fr auto;gap:2px 24px;margin:7px 0 0;padding:0 6%;font-size:12px;line-height:1.6;display:grid}.science-fc-figure figcaption strong{color:var(--ink);grid-column:1;font-size:15px;font-weight:500}.science-fc-figure figcaption>span{grid-column:1}.science-fc-figure figcaption a{color:var(--ink);grid-area:1/2/span 2;align-self:center;padding-block:12px}.science-opening-nav{border-top-color:#d3d3d3}.science-opening-nav a{border-right:0;justify-content:center;padding:15px 12px;font-size:14px;font-weight:500}.science-section-jump{display:none}.capability-chapter{background:var(--canvas);border-bottom:1px solid #d3d3d3;padding-top:56px;padding-bottom:58px}.capability-chapter .chapter-heading{margin-bottom:28px}.capability-chapter .platform-operations{align-items:start;margin-top:28px;padding-top:28px}.capability-chapter .platform-operations h3{margin-top:12px;font-size:28px;font-weight:400}.capability-chapter .platform-operations p{font-size:15px;line-height:1.75}.capability-chapter .platform-operations figcaption,.capability-chapter .platform-operations a{font-size:13px}.capability-chapter .platform-operations figcaption a{text-underline-offset:3px;text-decoration:underline}.capability-chapter .research-citation{margin-top:28px;font-size:14px}.research-page .pipeline-ownership{max-width:940px;margin:-6px 0 24px;font-size:16px;line-height:1.7}.science-foundation{--foundation-inset:66px;padding-top:var(--foundation-inset);scroll-margin-top:calc(-1 * var(--foundation-inset));padding-bottom:70px}.foundation-inspection,.foundation-explanation{display:block}.foundation-molecular-term{white-space:nowrap}.foundation-introduction{grid-template-columns:minmax(0,.82fr) minmax(0,1.18fr);align-items:start;gap:clamp(36px,7vw,100px);display:grid}.foundation-introduction>h2{letter-spacing:-.025em;text-wrap:balance;margin:0;font-size:clamp(28px,2.8vw,40px);font-weight:400;line-height:1.15}.foundation-explanation h3{letter-spacing:-.015em;margin:0 0 12px;font-size:20px;font-weight:500;line-height:1.35}.foundation-explanation p{margin:0;font-size:16px;line-height:1.75}.foundation-explanation .foundation-design-rationale{margin:0;font-size:17px}.fusion-design{grid-template-columns:minmax(0,.82fr) minmax(0,1.18fr);align-items:center;gap:clamp(36px,7vw,100px);margin-top:36px;display:grid}.fusion-design-figure{min-width:0;max-width:440px;margin:0}.fusion-design-caption>span{color:var(--ink);letter-spacing:-.015em;font-size:20px;font-weight:500}.fusion-design-caption p{color:#666;margin-top:3px;font-size:14px}.fusion-design-illustration{width:100%;height:auto;margin:12px 0 0;display:block}.foundation-explanation .fusion-design-note{color:#666;margin-top:0;font-size:12px;line-height:1.6}.fusion-design-note a{color:var(--ink);text-underline-offset:3px;white-space:nowrap;text-decoration:underline}.foundation-principles{gap:38px;padding-block:16px;display:grid}.foundation-principles article{border-left:2px solid var(--ink);padding-left:23px;position:relative}.foundation-principles article:first-child{border-color:var(--cyan)}.foundation-study{border-top:1px solid var(--ink);min-width:0;margin:44px 0 0;padding-top:28px}.foundation-study-instrument{color:var(--ink);grid-template-columns:minmax(0,.82fr) minmax(0,1.18fr);gap:22px clamp(36px,7vw,100px);margin:0;padding:0;display:grid}.foundation-study-instrument>.foundation-study-heading{letter-spacing:0;margin:0}.foundation-study .foundation-study-heading h3{color:var(--ink);letter-spacing:-.02em;text-wrap:balance;margin:0 0 9px;font-size:28px;font-weight:400;line-height:1.3}.foundation-title-phrase{white-space:nowrap}.foundation-study-heading>p{color:#666;margin:0;font-size:13px}.foundation-comparison{grid-column:1/-1;grid-template-columns:repeat(4,minmax(0,1fr));gap:2px;display:grid}.foundation-comparison>.foundation-panel{min-width:0;margin:0;display:block}.foundation-comparison .foundation-panel-label{background:var(--ink);color:#fff;letter-spacing:0;font-variant-numeric:tabular-nums;justify-content:space-between;align-items:center;min-height:44px;margin:0;padding:9px 14px;font-size:14px;line-height:1.5;display:flex}.foundation-study .foundation-image-finding{color:#333;margin:0;font-size:15px;line-height:1.7}.foundation-micrograph{aspect-ratio:635/615;width:100%;height:auto;display:block;overflow:hidden}.foundation-study .foundation-image-legend{color:#666;grid-column:1/-1;margin:-10px 0 0;font-size:13px}.foundation-study .foundation-image-method,.foundation-study .foundation-image-limit{color:#666;max-width:90ch;margin:16px 0 0;font-size:14px;line-height:1.65}.foundation-mouse-study{border-top:1px solid #d3d3d3;grid-template-columns:minmax(0,.82fr) minmax(0,1.18fr);gap:clamp(36px,7vw,100px);margin-top:36px;padding-top:28px;display:grid}.foundation-mouse-study h3{margin:0;font-size:22px;font-weight:500;line-height:1.35}.foundation-mouse-study p{margin:0;font-size:16px;line-height:1.75}.foundation-method-details{border-top:1px solid #d3d3d3;margin-top:14px}.foundation-method-details summary{min-height:44px;color:var(--ink);cursor:pointer;padding:12px 0;font-size:14px}.foundation-method-details summary:focus-visible{outline:2px solid var(--ink);outline-offset:3px}.foundation-method-details .foundation-image-method{margin-top:0}.foundation-image-source{flex-wrap:wrap;gap:9px 20px;margin-top:19px;font-size:13px;line-height:1.6;display:flex}.foundation-image-source a{color:var(--ink);text-underline-offset:3px;text-decoration:underline}.foundation-image-source>span{color:#666;flex-basis:100%}.science-foundation .research-citation{font-size:14px}.research-page .chapter-heading .eyebrow{letter-spacing:0;text-transform:none;font-size:14px;font-weight:500}.research-page .chapter-heading h2{letter-spacing:-.03em;font-size:clamp(30px,3.2vw,46px);font-weight:400}@media (max-width:1050px){.science-opening{gap:3%}.science-opening-copy{padding-block:24px}.science-page-label{margin-bottom:20px}.science-opening h1{margin-bottom:22px;font-size:42px}.research-page .science-opening-rationale{font-size:16px}.science-opening-actions{gap:8px 20px;margin-top:20px}.science-fc-figure figcaption{column-gap:10px;padding-inline:0}}@media (max-width:900px){.foundation-comparison{grid-template-columns:repeat(2,minmax(0,1fr));gap:12px 2px}}@media (min-width:761px) and (max-width:1050px){.fusion-design{grid-template-columns:minmax(0,1fr) minmax(0,1.15fr);gap:32px}.fusion-design-labels text[font-size="17"]{font-size:25px}}@media (max-width:760px){.science-opening{grid-template-columns:minmax(0,1fr);gap:0;padding:29px 4.5% 24px}.science-opening-copy{max-width:580px;padding-block:0}.science-page-label{margin-bottom:19px;font-size:14px}.science-opening h1{max-width:510px;margin-bottom:19px;font-size:clamp(32px,7.3vw,46px);line-height:1.12}.research-page .science-opening-rationale{max-width:550px;font-size:16px;line-height:1.65}.science-opening-actions{gap:8px 24px;margin-top:13px}.science-opening-actions a{gap:12px;font-size:14px}.science-fc-figure{width:100%;max-width:540px;margin:8px auto 0}.science-fc-figure>img{height:clamp(240px,75vw,440px)}.science-fc-figure figcaption{margin-top:0}.science-opening-nav{display:block}.science-opening-nav>a{display:none}.science-section-jump{color:#666;align-items:center;gap:18px;min-height:50px;font-size:14px;display:flex}.science-section-jump span{flex-shrink:0}.science-section-jump select{min-width:0;max-width:100%;min-height:44px;font:inherit;color:var(--ink);background:#fff;border:0;flex:1;padding:9px 6px}.science-foundation{--foundation-inset:42px;padding-bottom:44px}.capability-chapter{padding-top:38px;padding-bottom:40px}.capability-chapter .chapter-heading{margin-bottom:24px}.capability-chapter .platform-operations{gap:28px;margin-top:24px;padding-top:24px}.capability-chapter .platform-operations h3{font-size:26px}.research-page .pipeline-ownership{margin-bottom:22px;font-size:15px}.foundation-introduction,.fusion-design,.foundation-study-instrument,.foundation-mouse-study{grid-template-columns:minmax(0,1fr);gap:24px}.foundation-introduction>h2{margin-bottom:0;font-size:30px}.foundation-explanation h3{font-size:20px}.fusion-design{gap:28px;margin-top:26px}.foundation-introduction{gap:17px}.fusion-design-figure{flex-direction:column;max-width:100%;display:flex}.fusion-design-caption{order:1;margin-top:8px}.fusion-design-caption>span{font-size:18px}.fusion-design-caption p{font-size:13px;line-height:1.5}.foundation-explanation .fusion-design-note{order:2;margin-top:10px}.fusion-design-illustration{max-width:320px;margin:0 auto}.foundation-principles{gap:24px;padding-block:0}.foundation-principles article{padding-left:18px}.fusion-design-labels text[font-size="17"]{font-size:25px}.foundation-principles p{line-height:1.65}.foundation-study{margin-top:36px;padding-top:24px}.foundation-study .foundation-study-heading h3{font-size:24px}.foundation-study-heading>p{margin-bottom:0}.foundation-comparison .foundation-panel-label{min-height:40px;padding-inline:10px;font-size:13px}.foundation-mouse-study{gap:16px}.research-page .chapter-heading h2{font-size:32px}}html[lang=zh-CN] .science-opening h1{letter-spacing:0;font-size:clamp(36px,3.65vw,52px);line-height:1.22}.science-title-phrase{white-space:nowrap;display:block}html[lang=zh-CN] .research-page .science-opening-rationale{max-width:26em;line-height:1.8}html[lang=zh-CN] .research-page .chapter-heading h2,html[lang=zh-CN] .foundation-introduction>h2,html[lang=zh-CN] .capability-chapter .platform-operations h3{letter-spacing:0;line-height:1.3}.research-page .clinical-study-note,.research-page .clinical-study-result>p:last-child{font-size:14px;line-height:1.7}.research-page .study-bar>span{font-size:13px}@media (max-width:1050px){html[lang=zh-CN] .science-opening h1{font-size:35px}}@media (max-width:760px){html[lang=zh-CN] .science-opening h1{font-size:clamp(30px,8.2vw,40px)}}@media (max-width:360px){.science-opening h1{font-size:31px}.science-opening-actions{gap:0 19px}.science-opening-actions a{gap:8px;font-size:13px}.science-fc-figure figcaption{column-gap:5px;font-size:11px}.science-fc-figure figcaption strong{font-size:14px}}.company-page,.company-directory{--company-gutter:clamp(22px, 4.5vw, 64.8px);color:#333}.company-page h1,.company-page h2,.company-page h3,.company-directory h1,.company-directory h2{font-family:var(--sans);letter-spacing:-.025em;text-wrap:balance;color:var(--ink)}.company-page p,.company-directory p{line-height:1.72}.company-page .company-kicker{color:#666;letter-spacing:.08em;margin:0 0 25px;font-size:12px;font-weight:500}.company-opening{padding:48px var(--company-gutter) 38px;grid-template-columns:minmax(0,.82fr) minmax(0,1.18fr);align-items:center;gap:clamp(40px,5vw,90px);max-width:1720px;margin:0 auto;display:grid}.company-opening-copy{max-width:520px}.company-page .company-opening h1{color:var(--red);margin:0 0 30px;font-size:clamp(46px,4.45vw,64px);font-weight:500;line-height:1.04}.company-opening .company-opening-intro{margin:0 0 28px;font-size:18px;line-height:1.75}.company-inline-link,.company-back-link{color:var(--ink);text-underline-offset:6px;align-items:baseline;gap:16px;font-size:14px;font-weight:500;-webkit-text-decoration:underline #ccc;text-decoration:underline #ccc;display:inline-flex}.company-inline-link:hover,.company-back-link:hover{text-decoration-color:currentColor}.company-listing-photo{min-width:0;margin:0}.company-listing-photo>img{aspect-ratio:1.35;object-fit:cover;object-position:50% 50%;width:100%;height:auto;display:block}.company-listing-photo figcaption{color:#666;flex-wrap:wrap;justify-content:space-between;align-items:baseline;gap:5px 18px;padding-top:12px;font-size:12px;line-height:1.5;display:flex}.company-listing-photo figcaption a{color:var(--ink)}.company-listing-photo figcaption a:hover{text-underline-offset:3px;text-decoration:underline}.company-section-nav{margin:0 var(--company-gutter);color:var(--ink);border-top:1px solid #ccc;border-bottom:1px solid #ccc;flex-wrap:wrap;justify-content:space-between;gap:12px 24px;padding:22px 0;font-size:13px;font-weight:500;line-height:1.5;display:flex}.company-section-nav a:hover{text-underline-offset:5px;text-decoration:underline}.company-focus,.company-platform,.company-history,.company-leadership-intro{grid-template-columns:minmax(0,.82fr) minmax(0,1.18fr);gap:clamp(40px,5vw,90px);display:grid}.company-focus,.company-platform,.company-history,.company-leadership{padding:64px var(--company-gutter);max-width:1720px;margin:0 auto}.company-focus h2,.company-platform h2,.company-history h2,.company-leadership h2{max-width:450px;margin:0 0 26px;font-size:clamp(28px,2.4vw,35px);font-weight:500;line-height:1.16}.company-focus-copy,.company-platform-copy,.company-leadership-intro>div:last-child{max-width:720px;font-size:16px}.company-focus-copy p,.company-platform-copy p{margin-bottom:22px}.company-focus-copy p:last-child,.company-platform-copy p:last-child{margin-bottom:0}.company-focus-copy .company-origin-note{color:#666;font-size:14px}.company-platform{padding-top:0;padding-bottom:44px}.company-platform-title,.company-platform-copy{border-top:1px solid #ccc;padding-top:34px}.company-platform h2{font-size:clamp(25px,2.25vw,34px)}.company-operation+.company-operation{margin-top:30px}.company-platform-copy .company-operation h3{text-wrap:initial;margin:0 0 12px;font-size:20px;font-weight:500;line-height:1.35}.company-operation p+p{margin-top:16px}.company-page .company-sources{color:var(--ink);flex-wrap:wrap;gap:9px 24px;margin-top:28px;font-size:12px;display:flex}.company-sources a{text-underline-offset:4px;-webkit-text-decoration:underline #ccc;text-decoration:underline #ccc}.company-purpose{background:var(--ink);color:#fff;padding:58px var(--company-gutter) 62px;grid-template-columns:1fr 1fr;gap:36px 10%;display:grid}.company-purpose>div{max-width:640px}.company-purpose .company-kicker{color:#fff;margin-bottom:25px}.company-page .company-purpose h2{color:#fff;margin:0 0 24px;font-size:clamp(27px,2.5vw,38px);font-weight:400;line-height:1.22}.company-purpose p:last-child{margin-bottom:0;font-size:16px}.company-history{align-items:start;padding-bottom:78px;position:relative}.company-history>#\31 ,.company-leadership>#\32 {position:absolute;top:0}.company-history-range{color:#666;letter-spacing:.04em;font-size:15px}.company-award{align-items:center;gap:20px;max-width:330px;margin:22px 0 0;display:flex}.company-award img{flex-shrink:0;width:68px;height:auto}.company-award figcaption{color:#666;text-wrap:balance;max-width:190px;font-size:12px;line-height:1.6}.company-timeline{margin:0;padding:0;list-style:none}.company-timeline>li{border-top:1px solid #ccc;grid-template-columns:80px minmax(0,1fr);align-items:baseline;gap:30px;padding:21px 0;display:grid}.company-timeline>li:first-child{border-top:2px solid var(--red);padding-top:23px}.company-timeline>li>time{color:var(--ink);font-variant-numeric:tabular-nums;font-size:24px;line-height:1.2}.company-timeline>li:first-child>time{color:var(--red)}.company-timeline p{margin:0;font-size:15px}.company-year-events{margin:0;padding:0;list-style:none}.company-year-events>li+li{margin-top:12px}.company-year-events time{color:var(--ink);font-size:inherit;white-space:nowrap;font-weight:500}.company-leadership{border-top:1px solid #ccc;padding-top:56px;position:relative}.company-leadership-intro p{margin-bottom:18px}.company-people{grid-template-columns:repeat(4,minmax(0,1fr));gap:clamp(22px,3vw,48px);margin-top:50px;display:grid}.company-person{flex-direction:column;align-items:start;display:flex}.company-person>img{aspect-ratio:3/4;object-fit:cover;object-position:50% 0;filter:none;background:#f5f5f5;width:100%;height:auto}.company-person>div{flex-direction:column;flex:1;width:100%;padding-top:22px;display:flex}.company-person h3{margin:0 0 9px;font-size:clamp(19px,1.7vw,25px);line-height:1.25}.company-person p{margin:0 0 18px;font-size:14px;line-height:1.55}.company-person-action{color:var(--ink);border-top:1px solid #ccc;justify-content:space-between;gap:20px;width:100%;margin-top:auto;padding-top:13px;font-size:13px;display:inline-flex}.company-person:hover h3{text-underline-offset:5px;text-decoration:underline;text-decoration-thickness:1px}.company-next{padding:0 var(--company-gutter) 80px;grid-template-columns:repeat(3,minmax(0,1fr));gap:4%;max-width:1720px;margin:0 auto;display:grid}.company-next a{color:var(--ink);border-top:1px solid #999;justify-content:space-between;align-items:baseline;gap:20px;padding:23px 0;font-size:clamp(18px,1.8vw,25px);line-height:1.3;display:flex}.company-next a:hover{border-color:var(--red)}.company-directory{padding:54px var(--company-gutter) 90px;max-width:1500px;margin:0 auto}.company-directory-heading{grid-template-columns:1fr 1fr;align-items:end;column-gap:8%;padding-bottom:45px;display:grid}.company-directory-heading .company-back-link{grid-column:1/-1;justify-self:start;margin-bottom:37px}.company-directory-heading h1{color:var(--red);margin:0;font-size:clamp(38px,4.5vw,65px);font-weight:500;line-height:1.06}.company-directory-heading p{max-width:570px;margin:0;font-size:16px}.company-directory-note{color:#555;max-width:70ch;margin:24px 0 0;font-size:14px;line-height:1.65}.company-directory-note a{text-underline-offset:3px;text-decoration:underline}.company-institution-list{border-top:1px solid #999;grid-template-columns:repeat(3,minmax(0,1fr));column-gap:5%;display:grid}.company-institution{border-bottom:1px solid #ccc;flex-direction:column;align-items:start;gap:24px;min-width:0;padding:30px 0;display:flex}.company-institution h2{text-wrap:initial;margin:0;font-size:clamp(20px,1.6vw,23px);line-height:1.25}.company-institution>span{width:100%;color:var(--ink);justify-content:space-between;gap:20px;margin-top:auto;font-size:12px;display:flex}.company-institution:hover h2{text-underline-offset:5px;text-decoration:underline;text-decoration-thickness:1px}.company-institution-mark{background:#fff;align-items:center;width:min(100%,250px);height:100px;display:flex}.company-institution-mark img{object-fit:contain;object-position:left center;width:100%;height:100%;display:block}@media (max-width:1050px){.company-institution-list{grid-template-columns:repeat(2,minmax(0,1fr))}.company-opening,.company-focus,.company-platform,.company-history,.company-leadership-intro{grid-template-columns:minmax(0,.9fr) minmax(0,1.1fr);column-gap:38px}.company-opening{padding-top:44px}.company-page .company-opening h1{font-size:54px}.company-opening .company-opening-intro{font-size:17px}.company-listing-photo>img{aspect-ratio:1.1}.company-people{grid-template-columns:repeat(2,minmax(0,1fr));gap:42px 32px}.company-person>img{max-height:420px}.company-person h3{font-size:24px}.company-purpose{column-gap:7%}.company-timeline>li{grid-template-columns:65px minmax(0,1fr);gap:15px}}@media (max-width:700px){.company-page,.company-directory{--company-gutter:22px}.company-opening,.company-focus,.company-platform,.company-history,.company-leadership-intro,.company-directory-heading{grid-template-columns:minmax(0,1fr);gap:28px;display:grid}.company-opening{padding-top:32px;padding-bottom:30px}.company-page .company-kicker{margin-bottom:19px}.company-page .company-opening h1{margin-bottom:22px;font-size:46px}.company-opening .company-opening-intro{margin-bottom:20px;font-size:17px}.company-listing-photo>img{aspect-ratio:1.5}.company-listing-photo figcaption{font-size:12px}.company-section-nav{justify-content:start;gap:13px 22px;padding:18px 0;font-size:13px}.company-focus,.company-history,.company-leadership{padding-top:48px;padding-bottom:48px}.company-focus h2,.company-platform h2,.company-history h2,.company-leadership h2{margin-bottom:20px;font-size:29px}.company-focus-copy,.company-platform-copy,.company-leadership-intro>div:last-child{font-size:16px}.company-platform{padding-top:0;padding-bottom:32px}.company-leadership{padding-top:36px}.company-platform-copy{border-top:0;padding-top:0}.company-platform-title{padding-top:32px}.company-purpose{grid-template-columns:minmax(0,1fr);gap:38px;padding-top:44px;padding-bottom:46px}.company-page .company-purpose h2{font-size:28px}.company-mission{border-top:1px solid #fff;padding-top:32px}.company-history{gap:32px}.company-history-range{margin-bottom:0}.company-award{gap:16px;max-width:100%;margin-top:20px}.company-award img{width:56px}.company-award figcaption{max-width:220px}.company-timeline>li{grid-template-columns:63px minmax(0,1fr);gap:16px;padding:20px 0}.company-timeline>li>time{font-size:24px}.company-timeline p{font-size:14px}.company-people{gap:30px 20px;margin-top:32px}.company-person>div{padding-top:15px}.company-person h3{font-size:20px}.company-person p{font-size:13px}.company-person-action{gap:10px;font-size:13px}.company-next{grid-template-columns:minmax(0,1fr);gap:0;padding-bottom:48px}.company-next a{padding:21px 0;font-size:21px}.company-directory{padding-top:30px;padding-bottom:50px}.company-directory-heading{gap:23px;padding-bottom:32px}.company-directory-heading .company-back-link{margin-bottom:10px}.company-directory-heading h1{font-size:42px}.company-institution-list{grid-template-columns:minmax(0,1fr)}.company-institution{gap:19px;padding:24px 0}.company-institution h2{font-size:23px}}@media (max-width:359px){.company-page,.company-directory{--company-gutter:22px}.company-people{grid-template-columns:minmax(0,1fr);gap:35px}.company-person{grid-template-columns:minmax(0,.82fr) minmax(0,1fr);align-items:start;gap:18px;display:grid}.company-person>div{padding-top:0}.company-person h3{font-size:20px}}.company-page:lang(zh) h1,.company-page:lang(zh) h2,.company-page:lang(zh) h3,.company-directory:lang(zh) h1,.company-directory:lang(zh) h2{letter-spacing:0}.company-page:lang(zh) .company-opening h1{font-size:clamp(44px,4.15vw,60px);line-height:1.16}.company-page:lang(zh) .company-opening-intro{font-size:17px;line-height:1.8}.company-page:lang(zh) .company-focus h2,.company-page:lang(zh) .company-platform h2,.company-page:lang(zh) .company-history h2,.company-page:lang(zh) .company-leadership h2,.company-page:lang(zh) .company-purpose h2{font-size:clamp(27px,2.2vw,32px);line-height:1.3}.company-page:lang(zh) .company-section-nav{font-size:14px}@media (max-width:700px){.company-page:lang(zh) .company-opening h1{font-size:44px}.company-page:lang(zh) .company-focus h2,.company-page:lang(zh) .company-platform h2,.company-page:lang(zh) .company-history h2,.company-page:lang(zh) .company-leadership h2,.company-page:lang(zh) .company-purpose h2{font-size:27px}}@media (not (max-width:700px)) and (max-width:1050px){.company-history{grid-template-columns:minmax(0,1fr);gap:32px 0}.company-history>.company-history-heading{grid-area:1/1;min-width:0}.company-history .company-history-range{margin-bottom:0}.company-history>.company-timeline{grid-area:2/1;justify-self:start;width:min(100%,730px);min-width:0}}@media (not (max-width:1050px)) and (not (min-width:1440px)){.company-history{--history-column-gap:clamp(32px, calc(10.2828vw - 76.072px), 72px);grid-template-columns:minmax(210px, 1fr) min(730.67px, calc(100% - 210px - var(--history-column-gap)));column-gap:var(--history-column-gap)}.company-history>.company-history-heading{grid-area:1/1;min-width:0}.company-history>.company-timeline{grid-area:1/2;min-width:0}}@font-face{font-family:IBM Plex Sans;src:url(/assets/fonts/ibm-plex-sans/plex-400.woff2)format("woff2");font-weight:400;font-display:swap}@font-face{font-family:IBM Plex Sans;src:url(/assets/fonts/ibm-plex-sans/plex-500.woff2)format("woff2");font-weight:500;font-display:swap}@font-face{font-family:IBM Plex Sans;src:url(/assets/fonts/ibm-plex-sans/plex-600.woff2)format("woff2");font-weight:600;font-display:swap}:root{--sans:"IBM Plex Sans", "PingFang SC", "Microsoft YaHei", sans-serif;--serif:"IBM Plex Sans", "PingFang SC", "Microsoft YaHei", sans-serif;--canvas:#fcfdfe;--frame-width:1440px}body{color:#333;background:var(--canvas)}.site{background:var(--canvas)}.site>main{max-width:var(--frame-width);margin-inline:auto}h1,h2,h3,h4,button,input,select{font-family:var(--sans)}h1,h2,h3{font-weight:500}strong,b{font-weight:600}html[lang=zh-CN] .site{line-break:strict}html[lang=zh-CN] .site :is(h1,h2,h3){letter-spacing:0}html[lang=zh-CN] .site .desktop-nav{gap:34px}html[lang=zh-CN] .site .desktop-nav a{font-size:16px}.site .site-header{background:#fff;border-bottom-color:#f5f5f5;width:100%;max-width:none;height:96px;min-height:96px;margin:0;padding-inline:max(4.5%,50vw - 655.2px)}.site-header .logo{width:126px}.site-header nav{font-size:14px;font-weight:500}.site .desktop-nav{gap:30px}.site .desktop-nav a{font-size:15px;font-weight:500}.site-header nav a{color:#333}.site-header nav a:hover,.site-header nav a[aria-current=page]{color:var(--ink)}.header-careers{color:#333;white-space:nowrap;font-size:14px;font-weight:500}.header-careers:hover,.header-careers[aria-current=page]{color:var(--ink);text-underline-offset:5px;text-decoration:underline}.page-heading h1,.detail-heading h1{font-family:var(--sans);color:var(--red);letter-spacing:-.035em}.page-heading>p:not(.eyebrow),.detail-subtitle{color:#333}.section>h2,.section-heading h2{font-family:var(--sans);color:var(--ink)}.article-body{color:#333}.article-body>p{line-height:1.8}.context-note h2,.source-supplement h2{color:var(--ink)}.news-row h2,.filing-title,.institution-grid h2{font-weight:500}.news-row:hover h2,.filing-title:hover{color:var(--ink)}.footer{color:var(--ink);border-top:3px solid var(--cyan);background:#fff;padding-inline:max(4.5%,50vw - 655.2px)}.footer-top>div:first-child>p,.footer-contact p:not(.eyebrow),.safety-strip strong{color:#333}.footer-contact .eyebrow,.footer-bottom{color:#666}.footer .safety-strip{border-color:#ccc}.footer a:hover{color:var(--ink);text-underline-offset:4px;text-decoration:underline}@media (max-width:1050px){.site .desktop-nav,html[lang=zh-CN] .site .desktop-nav{gap:18px}.site .desktop-nav a,html[lang=zh-CN] .site .desktop-nav a{font-size:14px}.header-actions{gap:10px}}@media (max-width:820px){.header-careers{display:none}}@media (max-width:760px){.site .site-header{height:82px;min-height:82px;padding-inline:22px}.site-header .logo{width:108px}.page-heading h1{letter-spacing:-.03em}}.clinical-program-picker{display:none}.clinical-program-identity h4:focus{outline:none}.clinical-program-columns,.clinical-program-item{grid-template-columns:minmax(160px,.55fr) minmax(0,1fr) minmax(0,1fr);column-gap:34px}.clinical-program-map .clinical-program-item p{font-size:15px;line-height:1.7}.clinical-program-map .clinical-program-identity p,.clinical-program-map .clinical-program-sources{font-size:13px}.clinical-publication a{font-weight:600}.clinical-company-start{border-top:1px solid var(--line);margin-top:4px;padding-top:12px}.clinical-source-label{color:#666;margin-bottom:6px;font-size:12px;display:block}.clinical-pipeline-link{text-underline-offset:3px;text-decoration:underline}.research-page .research-paper>p,.research-page .research-paper .paper-copy>p{font-size:15px}.research-page .research-paper .paper-limit{font-size:14px;line-height:1.75}html[lang=zh-CN] .clinical-program-map .clinical-program-item p{line-height:1.8}@media (max-width:760px){.clinical-program-item{grid-template-columns:minmax(0,1fr)}.clinical-program-map[data-enhanced=true] .clinical-program-picker{color:var(--ink);gap:9px;margin-bottom:4px;font-size:14px;font-weight:500;display:grid}.clinical-program-picker select{width:100%;min-width:0;max-width:100%;min-height:48px;color:var(--ink);font:inherit;background:#fff;border:1px solid #666;border-radius:0;padding:10px 12px;font-size:16px;font-weight:400;display:block}.clinical-program-picker select:focus-visible{outline:2px solid var(--ink);outline-offset:3px}.clinical-program-map[data-enhanced=true] .clinical-program-item[data-selected=false]{display:none}.clinical-program-map[data-enhanced=true] .clinical-program-item{border-top:0;padding-top:24px;padding-bottom:12px}.clinical-program-map .clinical-program-question,.clinical-program-map .clinical-program-evidence{margin-left:0}.clinical-program-map .clinical-program-item p{font-size:15px;line-height:1.7}.clinical-program-map .clinical-program-identity p{font-size:13px}.clinical-program-map .clinical-program-sources{gap:13px;margin-top:20px;font-size:13px}.clinical-program-map .clinical-program-sources time{font-size:12px}}html:has([id^=clinical-study-]:target){scroll-behavior:auto}.careers-page{--career-line:#d8e0e7}.careers-welcome{padding:66px 4.5% 62px}.careers-intro{grid-template-columns:1.65fr 1fr;align-items:end;gap:9%;display:grid}.careers-intro .eyebrow{margin-bottom:24px}.site .careers-intro h1{color:var(--red);letter-spacing:-.045em;text-wrap:balance;max-width:760px;margin:0;font-size:clamp(42px,4.4vw,63px);font-weight:500;line-height:1.1}.site .careers-intro:lang(zh) h1{letter-spacing:-.02em;font-size:clamp(36px,3.6vw,52px);line-height:1.3}.careers-intro h1 span{display:block}.careers-invitation>p{max-width:38ch;margin:0 0 23px;font-size:17px;line-height:1.65}.careers-primary{background:var(--ink);border:1px solid var(--ink);color:#fff;justify-content:space-between;align-items:center;gap:30px;min-height:50px;padding:13px 20px;font-size:15px;font-weight:500;transition:box-shadow .15s;display:inline-flex}.careers-primary span{font-size:22px;line-height:1}.site .careers-primary:is(:hover,:focus-visible){color:#fff;box-shadow:inset 0 -3px var(--cyan)}.careers-primary:focus-visible{outline-offset:4px}.career-company-links{flex-wrap:wrap;gap:10px 22px;margin-top:22px;font-size:13px;display:flex}.career-company-links a{min-height:28px}.career-openings{border-top:1px solid var(--ink);grid-template-columns:250px minmax(0,1fr);align-items:start;gap:8%;margin:0 4.5%;padding:40px 0 30px;scroll-margin-top:32px;display:grid}.career-browse{position:sticky;top:28px}.site .career-browse h2{letter-spacing:-.025em;text-wrap:balance;margin:0 0 28px;font-size:27px;line-height:1.3}@media (min-width:681px) and (max-width:1000px){.site .career-browse:lang(zh) h2{font-size:25px}}.career-team-options{gap:4px;display:grid}.career-team-options button{width:100%;color:var(--ink);text-align:left;font:inherit;cursor:pointer;background:0 0;border:0;justify-content:space-between;align-items:center;gap:18px;min-height:46px;padding:12px 14px;font-size:14px;display:flex}.career-team-options button[aria-pressed=true]{background:var(--ink);color:#fff;box-shadow:inset 3px 0 var(--cyan)}.career-team-options button:hover:not([aria-pressed=true]){background:#eef3f7}.career-team-options button>span:last-child{font-variant-numeric:tabular-nums;font-size:12px}.career-location{color:#526577;margin-top:30px;font-size:12px;display:block}.career-location select{width:100%;font:inherit;color:var(--ink);cursor:pointer;background:0 0;border:1px solid #b5c3ce;border-radius:0;min-height:46px;margin-top:8px;padding:12px;font-size:14px;display:block}.career-reset,.career-empty button{color:var(--ink);font:inherit;cursor:pointer;text-underline-offset:4px;background:0 0;border:0;padding:12px 0;font-size:13px;text-decoration:underline;display:block}.career-results-count{color:#526577;margin:4px 0 28px;font-size:13px}.career-result-group{margin-bottom:30px}.site .career-result-group>h3{border-bottom:1px solid var(--ink);color:var(--ink);margin:0;padding:13px 0;font-size:13px;font-weight:500}.career-result-group ul{margin:0;padding:0;list-style:none}.career-listing{border-bottom:1px solid var(--career-line);grid-template-columns:minmax(0,1fr) 84px 18px;align-items:start;gap:22px;padding:24px 0 25px;transition:box-shadow .15s;display:grid}.site .career-listing h4{letter-spacing:-.025em;color:var(--ink);margin:0 0 10px;font-size:23px;font-weight:500;line-height:1.3}.site .career-listing:lang(zh) h4{letter-spacing:0;font-size:21px;line-height:1.5}.career-listing p{color:#526577;max-width:66ch;margin:0;font-size:14px;line-height:1.6}.career-listing-location{color:#526577;padding-top:5px;font-size:13px}.career-listing-arrow{color:var(--ink);font-size:22px;line-height:1.3}.site .career-listing:is(:hover,:focus-visible){box-shadow:0 2px 0 var(--cyan);color:var(--ink)}.career-listing:is(:hover,:focus-visible) h4{text-underline-offset:5px;text-decoration:underline;text-decoration-thickness:1px}.career-empty{min-height:240px;padding:25px 0}.site .career-empty h3{font-size:23px}.careers-catalog-note{border-top:1px solid var(--career-line);color:#526577;justify-content:space-between;align-items:baseline;gap:26px;margin:0 4.5%;padding:22px 0 30px;font-size:12px;line-height:1.6;display:flex}.careers-catalog-note p{max-width:72ch;margin:0}.careers-catalog-note a{white-space:nowrap;color:var(--ink)}.careers-archive{border-top:1px solid var(--career-line);border-bottom:1px solid var(--career-line);margin:0 4.5% 70px;padding:23px 0;font-size:14px}.careers-archive summary{cursor:pointer;min-height:26px;color:var(--ink)}.careers-archive summary>span{color:#526577;margin-left:14px;font-size:12px}.careers-archive>p{color:#526577;margin:20px 0;font-size:13px}.careers-archive ul{margin:0;padding:0;list-style:none}.careers-archive li a{border-top:1px solid var(--career-line);justify-content:space-between;align-items:baseline;gap:22px;padding:16px 0;display:flex}.careers-archive li span{white-space:nowrap;font-size:12px}@media (max-width:1000px){.careers-intro{grid-template-columns:1.3fr 1fr;gap:6%}.career-openings{grid-template-columns:210px minmax(0,1fr);gap:5%}.career-listing{grid-template-columns:minmax(0,1fr) 18px;gap:8px 14px}.career-listing-location{grid-row:2;padding:0}.career-listing-arrow{grid-area:1/2}.careers-catalog-note{flex-wrap:wrap;gap:12px}}@media (max-width:680px){.careers-welcome{padding:38px 22px 35px}.careers-intro{display:block}.careers-intro .eyebrow{margin-bottom:20px}.site .careers-intro h1{max-width:14ch;font-size:clamp(36px,9.8vw,46px);line-height:1.13}.site .careers-intro:lang(zh) h1{max-width:none;font-size:clamp(28px,7.8vw,38px);line-height:1.4}.careers-invitation{margin-top:24px}.careers-invitation>p{max-width:44ch;margin-bottom:18px;font-size:15px}.careers-primary{min-height:48px;font-size:14px}.career-company-links{gap:9px 22px;margin-top:17px}.career-openings{margin:0 22px;padding-top:30px;scroll-margin-top:20px;display:block}.career-browse{position:static}.site .career-browse h2{margin-bottom:20px;font-size:25px}.career-team-options{grid-template-columns:1fr 1fr;gap:6px}.career-team-options button{border:1px solid var(--career-line);gap:8px;min-height:45px;padding:11px 10px;font-size:12px}.career-location{margin-top:19px}.career-location select{padding:10px 12px;font-size:15px}.career-results-count{margin:24px 0 15px}.career-listing{padding:20px 0}.site .career-listing h4{letter-spacing:-.02em;margin-bottom:8px;font-size:21px}.site .career-listing:lang(zh) h4{font-size:19px}.career-listing p{font-size:13px;line-height:1.65}.career-listing-location{margin-top:5px;font-size:12px}.careers-catalog-note{margin:0 22px}.careers-archive{margin:0 22px 44px}.careers-archive li a{display:block}.careers-archive li span{margin-top:7px;display:block}}.career-browse-heading{justify-content:space-between;align-items:baseline;gap:16px;display:flex}.career-filter-toggle{display:none}.site .career-results-count{font-size:13px}.site .careers-catalog-note p{font-size:12px}@media (max-width:680px){.career-filter-toggle{min-height:44px;color:var(--ink);font:inherit;cursor:pointer;background:0 0;border:0;flex-shrink:0;justify-content:space-between;align-items:center;gap:10px;padding:10px 0 10px 10px;font-size:12px;display:inline-flex}.career-browse-heading{align-items:center}.site .career-browse-heading h2{margin-bottom:0}.career-filter-controls[data-open=false]{display:none}.career-filter-controls[data-open=true]{padding-top:18px;padding-bottom:6px}.career-results-count{margin-top:16px}}.career-listing{grid-template-areas:"title location arrow""summary location arrow";row-gap:8px}.site .career-listing h4{grid-area:title;margin-bottom:0}.career-listing p{grid-area:summary}.career-listing-location{grid-area:location}.career-listing-arrow{grid-area:arrow}@media (max-width:1000px){.career-listing{grid-template-areas:"title arrow""location arrow""summary."}.career-listing-location{grid-area:location;margin:0}.career-listing-arrow{grid-area:arrow}}.career-listing .career-title-phrase{display:inline-block}.detail-job .detail-heading{border-bottom:1px solid #d7dee4;max-width:1100px;margin:0 auto 46px;padding-bottom:37px}.detail-job .back-link{color:var(--ink);margin-bottom:38px;font-size:14px}.detail-job .article-meta{flex-wrap:wrap;align-items:baseline;gap:10px 22px;margin-bottom:17px;font-size:13px}.detail-job .article-meta>span{color:var(--ink);font-weight:500}.site .detail-job .detail-heading h1{letter-spacing:-.03em;text-wrap:balance;max-width:890px;margin-bottom:19px;font-size:clamp(37px,4.1vw,57px);line-height:1.12}.detail-job .detail-heading .article-standfirst{max-width:770px;margin-bottom:0;font-size:19px;line-height:1.6}.detail-job .article-layout{grid-template-columns:minmax(0,1fr) 300px;grid-template-areas:"body aside";align-items:start;gap:65px}.detail-job .article-body{grid-area:body}.detail-job .article-aside{border:0;grid-area:aside;padding:0;display:block}.detail-job .job-facts{margin-bottom:26px}.detail-job .job-facts h2{color:var(--ink);margin:0 0 10px;font-size:19px}.detail-job .job-facts dl{margin:0}.detail-job .job-facts dl>div{border-bottom:1px solid #d7dee4;padding:14px 0}.detail-job .job-facts dt{color:var(--muted);margin-bottom:4px;font-size:12px;line-height:1.5}.detail-job .job-facts dd{margin:0;font-size:15px;line-height:1.55}.detail-job .job-next-step{border-top:3px solid var(--cyan);color:var(--paper);background:var(--ink);margin-bottom:24px;padding:23px 23px 22px}.detail-job .job-next-step h2{color:var(--paper);letter-spacing:-.02em;margin:0 0 14px;font-size:24px;line-height:1.22}.detail-job .job-next-step p{color:var(--paper);margin:0 0 18px;font-size:14px;line-height:1.65}.detail-job .job-next-step .job-status{margin-bottom:15px;font-size:12px}.detail-job .job-opportunities-link{min-height:48px;color:var(--ink);background:var(--paper);justify-content:space-between;align-items:center;gap:12px;padding:12px 14px;font-size:14px;font-weight:500;line-height:1.45;transition:background-color .15s;display:flex}.detail-job .job-opportunities-link:hover{background:var(--cyan);color:var(--ink)}.detail-job .job-opportunities-link>span:last-child{flex-shrink:0;font-size:18px}.detail-job .job-next-step .job-portal-language{margin:10px 0 0;font-size:12px}.detail-job .article-provenance{border-top:1px solid #d7dee4;padding-top:17px;font-size:13px}.detail-job .article-provenance summary{min-height:30px}.detail-job .article-aside .article-provenance p{font-size:13px;line-height:1.65}.detail-job .article-body>p{margin-bottom:18px;font-size:17px;line-height:1.8}.detail-job .article-body .job-section-heading{color:var(--ink);margin-top:35px;margin-bottom:15px;font-size:22px;line-height:1.4}.detail-job .article-body .job-section-heading:first-child,.detail-job .article-body>p:first-child{margin-top:0}.detail-job .article-body .job-subsection-heading{color:var(--ink);margin:25px 0 12px;font-size:18px;line-height:1.5}.detail-job .article-body li{line-height:1.75}.detail-job .article-body .context-note{margin-top:28px;font-size:13px;line-height:1.7}@media (max-width:1000px) and (min-width:761px){.detail-job .article-layout{grid-template-columns:minmax(0,1fr) 255px;gap:32px}.detail-job .job-next-step{padding:20px}.detail-job .job-next-step h2{font-size:22px}}@media (max-width:760px){.detail-job .detail-heading{margin-bottom:27px;padding-bottom:25px}.detail-job .back-link{margin-bottom:27px}.detail-job .article-meta{gap:6px 15px;font-size:12px}.site .detail-job .detail-heading h1{font-size:clamp(31px,8.5vw,43px);line-height:1.16}.detail-job .detail-heading .article-standfirst{font-size:17px;line-height:1.65}.detail-job .article-layout{grid-template-columns:1fr;grid-template-areas:"aside""body";gap:31px}.detail-job .job-facts dl{grid-template-columns:repeat(2,minmax(0,1fr));column-gap:22px;display:grid}.detail-job .job-facts dd{font-size:14px}.detail-job .job-next-step{margin-bottom:19px;padding:20px}.detail-job .job-next-step h2{margin-bottom:10px;font-size:23px}.detail-job .job-next-step .job-status{margin-bottom:11px}.detail-job .job-next-step p{margin-bottom:14px}.detail-job .article-body>p{font-size:16px;line-height:1.8}.detail-job .article-body .job-section-heading{font-size:21px}}@media (prefers-reduced-motion:reduce){.detail-job .job-opportunities-link{transition:none}}@media (max-width:760px){.detail-job .job-facts{margin-bottom:18px}.detail-job .job-facts h2{clip-path:inset(50%);white-space:nowrap;width:1px;height:1px;padding:0;position:absolute;overflow:hidden}.detail-job .job-facts dl:has(>div:only-child){display:block}.detail-job .job-facts dl>div{padding:0 0 12px}.detail-job .job-next-step{padding:17px 18px}.detail-job .job-next-step h2{font-size:20px}.detail-job .job-next-step .job-status{display:none}}.job-detail-bottom{flex-wrap:wrap;justify-content:space-between;align-items:center;gap:18px 30px;display:flex}@media (max-width:760px){.detail-job .job-fact-wide{grid-column:1/-1}.detail-job .job-facts dl{row-gap:13px}}.current-job{max-width:1220px;margin:0 auto;padding:46px 4.5% 76px}.current-job-heading{border-bottom:1px solid #ccd7df;padding-bottom:30px}.current-job-heading .back-link{margin-bottom:38px;font-size:13px}.current-job-department{color:#526577;margin:0 0 16px;font-size:13px}.site .current-job h1{letter-spacing:-.035em;text-wrap:balance;max-width:990px;margin:0 0 24px;font-size:clamp(36px,3.65vw,52px);font-weight:500;line-height:1.14}.site .current-job:lang(zh) h1{letter-spacing:-.015em;font-size:clamp(30px,3.2vw,45px);line-height:1.4}.current-job-basics{color:#526577;flex-wrap:wrap;gap:10px 24px;font-size:14px;display:flex}.current-job-basics span+span{border-left:1px solid #bccbd6;padding-left:24px}.site .current-job-posted{color:#526577;margin:14px 0 0;font-size:13px;line-height:1.6}.current-job-layout{grid-template-columns:minmax(0,1fr) 260px;align-items:start;gap:8%;padding-top:36px;display:grid}.current-job-body{min-width:0}.current-job-overview{color:var(--ink);margin:0 0 36px;font-size:19px;line-height:1.65}.job-editorial>section{margin-bottom:36px;scroll-margin-top:28px}.site .job-editorial h2{letter-spacing:-.02em;margin:0 0 18px;font-size:24px;font-weight:500;line-height:1.35}.job-editorial p,.job-editorial li{color:#253d50;font-size:16px;line-height:1.8}.job-editorial p{margin:0 0 16px}.job-editorial ul{margin:0;padding-left:20px}.job-editorial li{margin-bottom:13px;padding-left:5px}.job-editorial li::marker{color:var(--ink);font-size:.72em}.current-job-aside{position:sticky;top:28px}.current-job-aside .careers-primary{width:100%;display:flex}.current-job-apply-note{color:#526577;margin:11px 0 24px;font-size:11px;line-height:1.6}.current-job-aside nav p{color:#526577;margin:0 0 8px;font-size:11px}.current-job-aside nav a{padding:7px 0;font-size:13px;line-height:1.5;display:block}.current-job-checked{color:#526577;margin-top:22px;font-size:11px;line-height:1.6}.current-job-original{border-top:1px solid #d8e0e7;border-bottom:1px solid #d8e0e7;margin-top:30px;padding:20px 0;font-size:13px}.current-job-original summary{cursor:pointer;min-height:24px}.current-job-original>div{padding-top:20px}.current-job-original p{white-space:pre-line;overflow-wrap:anywhere;font-size:14px;line-height:1.8}.site .current-job-original h2{font-size:21px;line-height:1.5}.site .current-job-original h3{margin-top:20px;font-size:17px}.current-job-bottom{flex-wrap:wrap;justify-content:space-between;gap:24px;padding-top:28px;font-size:13px;display:flex}@media (max-width:1000px){.current-job-layout{grid-template-columns:minmax(0,1fr) 220px;gap:5%}.current-job-aside .careers-primary{gap:15px;padding:12px 15px}}@media (max-width:680px){.current-job{padding:28px 22px 50px}.current-job-heading .back-link{margin-bottom:27px}.current-job-department{margin-bottom:13px;font-size:12px;line-height:1.6}.site .current-job h1{margin-bottom:22px;font-size:clamp(30px,8.5vw,38px);line-height:1.18}.site .current-job:lang(zh) h1{font-size:clamp(27px,7vw,34px);line-height:1.4}.current-job-basics{gap:9px 15px;font-size:12px}.current-job-basics span+span{padding-left:15px}.current-job-heading{padding-bottom:25px}.current-job-layout{flex-direction:column;gap:22px;padding-top:23px;display:flex}.current-job-aside{border-bottom:1px solid #d8e0e7;order:-1;width:100%;position:static}.current-job-aside .careers-primary{max-width:320px;min-height:47px}.current-job-aside nav,.current-job-checked{display:none}.current-job-apply-note{margin-bottom:20px;font-size:11px}.current-job-overview{margin-bottom:29px;font-size:17px;line-height:1.75}.site .job-editorial h2{margin-bottom:16px;font-size:22px}.job-editorial p,.job-editorial li{font-size:15px;line-height:1.8}.job-editorial>section{margin-bottom:29px}.current-job-bottom{font-size:12px}}.site .current-job h1{color:var(--ink)}.site .current-job-department{font-size:13px}.site .current-job-overview{font-size:19px}.site .current-job-apply-note,.site .current-job-checked,.site .current-job-aside nav p{font-size:11px}.job-editorial ul{list-style:outside}.job-title-specialty{letter-spacing:-.015em;margin-top:15px;font-size:.57em;font-weight:400;line-height:1.45;display:block}.job-title-phrase{display:inline-block}@media (max-width:680px){.site .current-job-overview{font-size:17px}.site .current-job-department{font-size:12px}.current-job-checked{margin:0 0 14px;display:block}.job-title-specialty{margin-top:13px;font-size:.64em}}.job-title-separator{clip-path:inset(50%);white-space:nowrap;border:0;width:1px;height:1px;margin:-1px;padding:0;position:absolute;overflow:hidden}.site .current-job-apply-note,.site .current-job-checked{font-size:12px}.navigation-progress{z-index:200;background:var(--red);opacity:0;transform-origin:0;pointer-events:none;height:2px;position:fixed;inset:0 0 auto;transform:scaleX(0)}.navigation-progress[data-pending=true]{opacity:1;transition:transform 6s cubic-bezier(.1,.8,.1,1) .15s,opacity 80ms linear .15s;transform:scaleX(.8)}a[data-pending=true]{cursor:progress}.mobile-menu-shell{display:none}@media (max-width:820px){.site .site-header{z-index:102;position:relative}.mobile-menu-shell{z-index:101;inset:var(--menu-top,82px) 0 0;visibility:hidden;pointer-events:none;transition:visibility 0s linear .18s;display:block;position:fixed}.mobile-menu-shell[data-open=true]{visibility:visible;pointer-events:auto;transition-delay:0s}.mobile-menu-scrim{opacity:0;cursor:default;touch-action:none;background:#1f4e7914;border:0;border-radius:0;width:100%;height:100%;margin:0;padding:0;transition:opacity .16s ease-out;position:absolute;inset:0}.mobile-menu-shell[data-open=true] .mobile-menu-scrim{opacity:1}.site .mobile-navigation{z-index:1;box-sizing:border-box;overscroll-behavior:contain;background:var(--canvas);border-bottom:1px solid var(--ink);clip-path:inset(0 0 100%);max-height:100%;padding:10px max(4.5%,22px) 20px;transition:clip-path .18s cubic-bezier(.2,.7,.2,1);position:relative;overflow-y:auto}.mobile-menu-shell[data-open=true] .mobile-navigation{clip-path:inset(0)}.site .mobile-navigation>a{box-sizing:border-box;min-height:62px;color:var(--ink);border-bottom:1px solid #1f4e7933;gap:24px;padding:14px 0;font-size:22px;line-height:1.35;text-decoration:none;position:relative}.site .mobile-navigation>a>.mobile-navigation-label{color:inherit;font-size:inherit;font-weight:400}.site .mobile-navigation>a>.mobile-navigation-arrow{flex-shrink:0;margin-left:auto;font-size:23px;line-height:1}.site .mobile-navigation>a[aria-current=page]{border-bottom-color:var(--ink)}.site .mobile-navigation>a[aria-current=page]:after{content:"";background:var(--red);width:26px;height:2px;position:absolute;bottom:-1px;left:0}.site .mobile-navigation>a[aria-current=page]>.mobile-navigation-label{font-weight:500}.site .mobile-navigation>div{color:var(--ink);gap:32px;margin-top:14px;font-size:14px}.mobile-navigation>div>a{align-items:center;min-height:44px;display:inline-flex}.mobile-navigation>div>a[aria-current=page]{text-decoration:underline;-webkit-text-decoration-color:var(--red);text-decoration-color:var(--red);text-underline-offset:6px}.site .mobile-navigation>a:focus-visible{outline-offset:2px}.mobile-navigation>div>a:focus-visible{outline-offset:2px}@media (hover:hover) and (pointer:fine){.site .mobile-navigation>a:hover .mobile-navigation-label{text-underline-offset:5px;text-decoration:underline;text-decoration-thickness:1px}}}@media (prefers-reduced-motion:reduce){.navigation-progress[data-pending=true],.mobile-menu-shell,.mobile-menu-scrim,.site .mobile-navigation{transition:none}}.site .action-feedback{color:#fff;touch-action:manipulation;background:#1f4e79;border:1px solid #1f4e79;justify-content:space-between;align-items:center;gap:28px;padding:12px 18px;font-size:15px;font-weight:500;line-height:1.6;text-decoration:none;transition:box-shadow .16s ease-out;display:inline-flex;position:relative;box-shadow:inset 0 0 0 100px #0000}.site .action-feedback.careers-primary{padding:13px 20px;line-height:1.4}.site .action-feedback .action-feedback-label{font:inherit;white-space:nowrap;transition:transform .11s ease-out;display:inline-block;transform:translateY(0)}.site .action-feedback .action-feedback-aperture{width:20px;height:20px;font-size:inherit;flex:0 0 20px;line-height:1;transition:transform .11s ease-out;position:relative;overflow:hidden;transform:translateY(0)}.site .action-feedback .action-feedback-track{align-items:center;gap:6px;width:46px;transition:transform .23s cubic-bezier(.22,.75,.25,1);display:flex;position:absolute;inset:0;transform:translate(-26px)}.site .action-feedback .action-feedback-arrow{flex:0 0 20px;width:20px;height:20px;display:block;position:relative}.action-feedback-arrow:before{content:"";background:currentColor;width:15px;height:1.5px;position:absolute;top:9.25px;left:2px}.action-feedback-arrow:after{content:"";border-top:1.5px solid;border-right:1.5px solid;width:7px;height:7px;position:absolute;top:6.25px;right:3px;transform:rotate(45deg)}.site .action-feedback[data-direction=down] .action-feedback-aperture{transform:rotate(90deg)}.site .action-feedback:is(:hover,:focus-visible,:active){color:#fff;box-shadow:none;background:#1f4e79;border-color:#1f4e79;text-decoration:none}.site .action-feedback:focus-visible{outline-offset:4px;outline:2px solid #1f4e79}@media (hover:hover) and (pointer:fine){.site .action-feedback:hover{box-shadow:inset 0 0 0 100px #0000000f}.site .action-feedback:hover .action-feedback-track{transform:translate(0)}}.site .action-feedback:is(:active,[data-held=true]){transition-duration:65ms;box-shadow:inset 0 0 0 100px #0000001f}.site .action-feedback:is(:active,[data-held=true]) .action-feedback-label,.site .action-feedback:is(:active,[data-held=true]) .action-feedback-aperture{transition-duration:65ms;transform:translateY(1px)}.site .action-feedback[data-direction=down]:is(:active,[data-held=true]) .action-feedback-aperture{transform:translateY(1px)rotate(90deg)}@media (max-width:700px){.site .action-feedback{min-height:48px;font-size:14px}.site .action-feedback.home-action{padding:10px 15px}}@media (prefers-reduced-motion:reduce){.site .action-feedback,.site .action-feedback *{transition:none!important}.site .action-feedback:hover .action-feedback-track{transform:translate(-26px)}.site .action-feedback:is(:active,[data-held=true]) .action-feedback-label,.site .action-feedback:is(:active,[data-held=true]) .action-feedback-aperture{transform:none}.site .action-feedback[data-direction=down]:is(:active,[data-held=true]) .action-feedback-aperture{transform:rotate(90deg)}}.site .section.follow-section{padding-top:24px;padding-bottom:24px}.follow-qr--expanded{margin:0}.follow-qr__body{align-items:center;gap:30px;display:flex}.follow-qr .follow-qr__body img{flex:none;width:172px;max-width:100%;height:172px;margin:0;display:block}.follow-qr__copy{min-width:0}.follow-qr .follow-qr__copy h2{color:var(--ink);margin:0 0 8px;font-size:23px;font-weight:500;line-height:1.3}.follow-qr .follow-qr__copy p{color:var(--muted);margin:0 0 5px;font-size:14px;line-height:1.6}.follow-qr .follow-qr__save{min-height:44px;color:var(--ink);text-underline-offset:5px;align-items:center;padding:9px 0;font-size:14px;line-height:1.5;text-decoration:underline;text-decoration-thickness:1px;display:inline-flex}.follow-qr .follow-qr__save:hover{text-decoration-thickness:2px}.follow-qr .follow-qr__save:focus-visible{outline:2px solid var(--ink);outline-offset:4px}.follow-qr summary:focus-visible{outline:2px solid var(--ink);outline-offset:4px}.follow-qr:not(.follow-qr--expanded) .follow-qr__body{flex-direction:column;align-items:flex-start;gap:10px;margin-top:18px}@media (max-width:520px){.follow-qr--expanded .follow-qr__body{flex-wrap:wrap;gap:18px 24px}.follow-qr--expanded .follow-qr__copy{flex:140px}.follow-qr .follow-qr__copy h2{font-size:20px}}.home-page .home-protein-art--fc{width:760px;height:520px;min-height:0;max-height:none;top:-4px;right:-20px}.fc-ribbon{pointer-events:none;z-index:1;width:100%;height:520px;position:absolute;top:0;left:0}.fc-ribbon-poster,.fc-ribbon-viewport{pointer-events:none;width:100%;height:100%;display:block;position:absolute;inset:0}.home-protein-art--fc .fc-ribbon-poster img{object-fit:contain;width:100%;height:100%;margin:0;display:block;position:static}.fc-ribbon-viewport{opacity:0}.fc-ribbon-viewport canvas{pointer-events:none;width:100%;height:100%;display:block}.fc-ribbon[data-ready=true] .fc-ribbon-viewport{opacity:1}.fc-ribbon[data-ready=true] .fc-ribbon-poster{opacity:0}@media (min-width:761px) and (max-width:1199px){.home-page .home-protein-art--fc{width:52vw;height:480px;right:0}.fc-ribbon{height:480px}}@media (max-width:760px){.home-page .home-protein-art--fc{width:calc(100% + 44px);height:clamp(280px,84vw,360px);min-height:0;max-height:none;margin:8px -22px 18px;position:relative;top:auto;left:auto;right:auto}.home-page:lang(en) .home-protein-art--fc{margin-top:8px}.fc-ribbon{height:100%}}@media (prefers-reduced-motion:reduce){.fc-ribbon[data-ready=true] .fc-ribbon-poster{opacity:1}.fc-ribbon .fc-ribbon-viewport{display:none}}body:has(.home-page) .home-protein-art--fc{container-type:inline-size}body:has(.home-page) .fc-ribbon-poster{overflow:hidden}@container (width<=610px){body:has(.home-page) .fc-ribbon-poster img{transform:translateY(-2%)scale(1.12)}}body:has(.home-page) .home-protein-art--fc .fc-ribbon{height:100%}body:has(.home-page) .home-intro-copy{display:contents}@media (max-width:820px){body:has(.home-page) .site .site-header{height:72px;min-height:72px}}@media (max-width:559px){body:has(.home-page) .home-opening{padding:20px 22px 0}body:has(.home-page) .home-introduction{flex-direction:column;width:100%;min-height:0;padding:0;display:flex}body:has(.home-page) .home-introduction .home-label{order:0}body:has(.home-page) .home-introduction h1{order:1}body:has(.home-page) .home-introduction .home-protein-art--fc{order:2}body:has(.home-page) .home-intro-aside{order:3}body:has(.home-page) .home-introduction .home-label{margin-bottom:14px}body:has(.home-page) .home-introduction h1{font-size:clamp(32px,10.25vw,40px);line-height:1.075}html[lang=zh-CN] body:has(.home-page) .home-introduction h1{font-size:clamp(32px,10.25vw,40px);line-height:1.15}body:has(.home-page) .home-page .home-protein-art--fc{width:calc(100% + 44px);height:clamp(238px,100svh - 430px,284px);margin:4px -22px 8px}body:has(.home-page) .home-intro-aside{padding-bottom:24px}body:has(.home-page) .home-page .home-intro-text{margin-top:0;margin-bottom:16px;font-size:16px;line-height:1.6}html[lang=zh-CN] body:has(.home-page) .home-intro-text{line-height:1.8}}@media (min-width:560px) and (max-width:820px){body:has(.home-page) .home-opening{padding:24px 28px 0}body:has(.home-page) .home-introduction{grid-template-columns:minmax(0,1fr) minmax(0,1fr);align-items:center;gap:0 20px;width:100%;min-height:0;padding:0 0 28px;display:grid}body:has(.home-page) .home-introduction .home-label{grid-area:1/1/auto/-1;justify-content:space-between;width:100%;margin:0 0 8px}body:has(.home-page) .home-introduction h1{white-space:pre-line;grid-area:2/1;width:auto;margin:0;font-size:clamp(34px,5.8vw,44px);line-height:1.1}html[lang=zh-CN] body:has(.home-page) .home-introduction h1{font-size:clamp(34px,5.8vw,44px);line-height:1.2}body:has(.home-page) .home-page .home-protein-art--fc{grid-area:2/2;width:calc(100% + 16px);height:clamp(270px,44vw,350px);min-height:0;margin:0 -8px;position:relative;inset:auto}body:has(.home-page) .home-intro-aside{grid-area:3/1/auto/-1;width:100%;max-width:620px;margin-top:8px;padding:0}body:has(.home-page) .home-page .home-intro-text{margin:0 0 18px;font-size:17px;line-height:1.65}html[lang=zh-CN] body:has(.home-page) .home-intro-text{line-height:1.8}body:has(.home-page) .home-corporate-context{grid-template-columns:1fr 1fr;gap:12px 24px;padding:20px 0;display:grid}body:has(.home-page) .home-corporate-context p{margin:0;font-size:13px}body:has(.home-page) .home-corporate-context a{grid-column:1/-1;margin:0}}@media (min-width:821px) and (max-width:1199px){body:has(.home-page) .home-introduction{grid-template-columns:minmax(0,1fr) minmax(0,1fr);align-items:start;column-gap:30px;width:100%;min-height:0;padding:32px 0;display:grid}body:has(.home-page) .home-intro-copy{grid-area:1/1;min-width:0;display:block}body:has(.home-page) .home-introduction .home-label{margin:0 0 18px}body:has(.home-page) .home-introduction h1{margin:0 0 22px;font-size:clamp(40px,4.5vw,52px);line-height:1.08}html[lang=zh-CN] body:has(.home-page) .home-introduction h1{font-size:clamp(40px,4.5vw,52px);line-height:1.18}body:has(.home-page) .home-intro-aside{width:100%;padding:0}body:has(.home-page) .home-page .home-intro-text{margin:0 0 20px;font-size:17px}body:has(.home-page) .home-page .home-protein-art--fc{grid-area:1/2;align-self:start;width:100%;height:clamp(330px,44vw,440px);margin:0;position:relative;inset:auto}}@media (min-width:821px) and (max-height:600px){body:has(.home-page) .site .site-header{height:72px;min-height:72px}body:has(.home-page) .home-introduction{min-height:0;padding-top:20px;padding-bottom:24px}body:has(.home-page) .home-introduction .home-label{margin-bottom:12px}body:has(.home-page) .home-introduction h1{margin-bottom:16px;font-size:clamp(38px,4.25vw,54px);line-height:1.06}html[lang=zh-CN] body:has(.home-page) .home-introduction h1{font-size:clamp(38px,4.25vw,54px);line-height:1.15}body:has(.home-page) .home-page .home-intro-text{margin-bottom:16px}body:has(.home-page) .home-page .home-protein-art--fc{height:clamp(280px,65svh,350px)}}.platform-study .platform-title-phrase{white-space:nowrap}.platform-study .platform-composition{margin-top:34px}.platform-study .platform-workflow{border-top:1px solid var(--ink);grid-template-columns:repeat(7,minmax(0,1fr));margin:0 0 46px;padding:0;list-style:none;display:grid}.platform-study .platform-workflow>li{color:var(--ink);min-width:0;padding:24px 24px 0 0;font-size:17px;font-weight:500;line-height:1.38;position:relative}.platform-study .platform-workflow>li:before{content:"";background:var(--canvas);border:1px solid var(--ink);border-radius:50%;width:7px;height:7px;position:absolute;top:-4px;left:0}.platform-study .platform-workflow>li:last-child{padding-right:0}.platform-study .platform-workflow>li:last-child:after{content:"";border-top:1px solid var(--ink);border-right:1px solid var(--ink);width:7px;height:7px;position:absolute;top:-4px;right:1px;transform:rotate(45deg)}.platform-study .platform-workflow small{color:#666;margin-top:6px;font-size:13px;font-weight:400;line-height:1.4;display:block}.platform-study .platform-production{grid-area:1/2;margin:0}.platform-study .platform-crop{width:100%;aspect-ratio:var(--crop-w) / var(--crop-h);display:block;position:relative;overflow:hidden}.site .platform-study .platform-crop img{width:calc(1152 / var(--crop-w) * 100%);max-width:none;height:auto;left:calc(var(--crop-x) / var(--crop-w) * -100%);top:calc(var(--crop-y) / var(--crop-h) * -100%);box-shadow:none;border:0;border-radius:0;margin:0;display:block;position:absolute}.platform-study .platform-production figcaption{color:#666;margin-top:12px;font-size:12px;line-height:1.5}.platform-study .platform-manufacturing{border-top:1px solid #d3d3d3;grid-template-columns:180px minmax(0,1fr);align-items:start;gap:28px;margin-top:32px;padding-top:21px;display:grid}.platform-study .platform-manufacturing h3{color:var(--ink);margin:0;font-size:16px;font-weight:500;line-height:1.5}.platform-study .platform-manufacturing p{max-width:850px;margin:0 0 9px;font-size:14px;line-height:1.7}.platform-study .platform-manufacturing a{text-underline-offset:4px;font-size:13px;text-decoration:underline}.platform-study .research-citation{margin-top:28px;padding-top:20px}@media (max-width:1100px){.platform-study .platform-workflow>li{padding-right:16px;font-size:15px}}@media (max-width:850px){.platform-study .platform-composition{grid-template-columns:minmax(0,.85fr) minmax(0,1.15fr);gap:28px 38px;margin-top:28px;display:grid}.platform-study .platform-workflow{border-top:0;align-self:start;margin:0;padding:0 0 0 16px;display:block}.platform-study .platform-workflow>li{border-left:0;padding:0 0 20px 22px;font-size:17px}.platform-study .platform-workflow>li:before{z-index:1;top:8px;left:-3px}.platform-study .platform-workflow>li:not(:last-child):after{content:"";background:var(--ink);width:1px;position:absolute;top:11px;bottom:-11px;left:0}.platform-study .platform-workflow>li:last-child{padding-bottom:0}.platform-study .platform-workflow>li:last-child:after{display:none}.platform-study .platform-production{grid-area:1/2;width:100%}.platform-study .platform-manufacturing{grid-area:3/1/auto/-1;grid-template-columns:150px minmax(0,1fr);margin-top:0}}@media (max-width:540px){.platform-study .platform-composition{margin-top:30px;display:block}.platform-study .platform-workflow{margin-bottom:32px;padding-left:4px}.platform-study .platform-workflow>li{padding-bottom:17px;font-size:17px}.platform-study .platform-workflow small{font-size:13px}.platform-study .platform-production{width:min(100%,400px);margin-bottom:28px}.platform-study .platform-manufacturing{margin-top:30px;padding-top:20px;display:block}.platform-study .platform-manufacturing h3{margin-bottom:10px}}.proposal-platform{padding-top:52px}.proposal-platform .chapter-heading{grid-template-columns:minmax(0,1fr) minmax(0,1.1fr);column-gap:7%;margin-bottom:32px}.proposal-platform .chapter-heading>p:last-child{max-width:650px;padding-left:25px}.proposal-platform .platform-title-phrase{white-space:nowrap}.proposal-platform .fusion-design{grid-template-columns:minmax(0,1fr) minmax(0,1.1fr);gap:7%;margin-top:0}.proposal-platform .fusion-design-figure{max-width:520px}.proposal-platform .fusion-design-illustration{margin-top:15px}.proposal-platform .foundation-principles{gap:32px}.proposal-platform .foundation-study{margin-top:44px}.proposal-platform .foundation-mouse-study{margin-top:28px;padding-top:25px}.proposal-development{border-top:1px solid #d3d3d3;padding-top:44px;padding-bottom:44px}.proposal-development>.chapter-heading{grid-template-columns:minmax(0,.8fr) minmax(0,1.2fr);column-gap:8%;margin-bottom:34px}.proposal-development>.chapter-heading h2{font-size:31px;line-height:1.2}.proposal-development .platform-composition{margin-top:0}.proposal-development .platform-workflow{margin-bottom:30px}.proposal-development .proposal-production{grid-template-columns:192px minmax(0,.85fr) minmax(0,1.35fr);align-items:start;gap:36px;display:grid}.proposal-development .platform-production{grid-area:auto;width:192px;margin:0}.proposal-development .platform-production figcaption{margin-top:9px}.proposal-development .proposal-equipment h3,.proposal-development .platform-manufacturing h3{color:var(--ink);margin:0 0 12px;font-size:16px;font-weight:500;line-height:1.4}.proposal-development .proposal-equipment p{margin:0 0 12px;font-size:16px;line-height:1.65}.proposal-development .proposal-equipment a{text-underline-offset:3px;font-size:13px;line-height:1.5;text-decoration:underline}.proposal-development .platform-manufacturing{border:0;margin:0;padding:0;display:block}.proposal-development .platform-manufacturing p{margin:0 0 12px;font-size:15px;line-height:1.65}.proposal-development .research-citation{margin-top:26px;padding-top:22px}@media (max-width:1100px){.proposal-development .proposal-production{grid-template-columns:164px minmax(0,1fr);gap:24px 32px}.proposal-development .platform-production{grid-row:1/3;width:164px}.proposal-development .platform-manufacturing{grid-column:2}}@media (max-width:850px){.proposal-development .platform-composition{display:block}.proposal-development .platform-workflow{grid-template-columns:1fr 1fr;gap:0 28px;margin:0 0 28px;padding:0;display:grid}.proposal-development .platform-workflow>li{border-bottom:1px solid #d3d3d3;padding:10px 0;font-size:16px}.proposal-development .platform-workflow>li:before,.proposal-development .platform-workflow>li:after{display:none!important}.proposal-development .platform-workflow>li:last-child{padding-bottom:10px}.proposal-development .platform-workflow>li{counter-increment:proposal-stage}.proposal-development .platform-workflow{counter-reset:proposal-stage}.proposal-development .platform-workflow>li:before{content:counter(proposal-stage, decimal-leading-zero);color:#666;background:0 0;border:0;margin-right:10px;font-size:12px;position:static;display:inline!important}.proposal-development .platform-workflow small{margin-left:25px}}@media (max-width:700px){.proposal-platform{padding-top:32px}.proposal-platform .chapter-heading{margin-bottom:28px;display:block}.proposal-platform .chapter-heading>p:last-child{margin-top:24px;padding-left:0}.proposal-platform .fusion-design{grid-template-columns:1fr;gap:26px}.proposal-platform .fusion-design-figure{max-width:100%}.proposal-platform .fusion-design-illustration{max-width:360px;margin:0 auto}.proposal-platform .foundation-principles{gap:24px}.proposal-development{padding-top:32px;padding-bottom:32px}.proposal-development>.chapter-heading{margin-bottom:20px;display:block}.proposal-development>.chapter-heading h2{margin-bottom:16px;font-size:28px}.proposal-development>.chapter-heading p{font-size:16px;line-height:1.65}.proposal-development .platform-workflow{grid-template-columns:1fr}.proposal-development .platform-workflow>li{padding-block:9px}.proposal-development .platform-workflow small{margin-left:8px;font-size:12px;display:inline}.proposal-development .proposal-production{grid-template-columns:128px minmax(0,1fr);gap:24px}.proposal-development .platform-production{grid-row:1;width:128px;margin-bottom:0}.proposal-development .platform-production figcaption{font-size:11px}.proposal-development .proposal-equipment h3{margin-bottom:8px;font-size:15px}.proposal-development .proposal-equipment p{margin-bottom:10px;font-size:15px;line-height:1.55}.proposal-development .platform-manufacturing{border-top:1px solid #d3d3d3;grid-column:1/-1;padding-top:20px}}.refined-platform .fusion-design-figure{container-type:inline-size}.refined-platform .fusion-design-labels text[font-size="17"]{font-size:17px}.refined-platform .refined-annotation-lines path{vector-effect:non-scaling-stroke;stroke-width:1px}.refined-platform .fusion-design-illustration{margin-top:20px}.refined-platform .fusion-design-caption{order:0;margin-top:0}.refined-platform .fusion-design-caption>span{font-size:20px}.refined-platform .fusion-design-caption p{font-size:14px}.refined-platform .foundation-principles{gap:30px}.refined-platform .foundation-principles p{max-width:58ch}.refined-platform .foundation-study{padding-top:30px}.refined-platform .foundation-study-instrument,.refined-platform .foundation-mouse-study{grid-template-columns:minmax(0,1fr) minmax(0,1.1fr);column-gap:7%}.refined-platform .foundation-study-heading .refined-foundation-eyebrow{color:var(--ink);margin:0 0 10px;font-size:14px;font-weight:500;line-height:1.5}.refined-platform .foundation-study-heading h3{margin-bottom:8px}.refined-platform .foundation-image-finding{align-self:end;padding-bottom:2px;padding-left:25px}.refined-platform .foundation-comparison{gap:2px}.refined-platform .foundation-panel-label{min-height:34px;color:var(--ink);background:0 0;padding:0 0 10px;font-size:14px;font-weight:500;line-height:1.5}.refined-platform .foundation-panel:not(:first-child) .foundation-panel-label{padding-left:10px}.refined-platform .refined-figure-notes{margin-top:14px}.refined-platform .refined-figure-notes .foundation-image-legend{margin:0;font-size:13px;line-height:1.6}.refined-platform .refined-figure-notes .foundation-image-limit{max-width:105ch;margin:10px 0 0;font-size:14px;line-height:1.65}.refined-platform .refined-figure-utilities{border-top:1px solid #d3d3d3;grid-template-columns:minmax(0,1fr) minmax(0,1.1fr);align-items:start;column-gap:7%;margin-top:16px;padding-top:2px;display:grid}.refined-platform .foundation-method-details{border:0;margin:0}.refined-platform .foundation-method-details summary{padding-block:11px}.refined-platform .foundation-method-details[open]{padding-bottom:4px}.refined-platform .foundation-image-source{align-items:start;gap:0 22px;margin:0;padding-left:25px;font-size:13px}.refined-platform .foundation-image-source>a{align-items:center;min-height:44px;padding-block:8px;display:inline-flex}.refined-platform .foundation-image-source>span{margin-top:0}.refined-platform .foundation-mouse-study{margin-top:30px}.refined-platform .foundation-mouse-study>p{padding-left:25px}@container (width<=480px){.refined-platform .fusion-design-labels text[font-size="17"]{font-size:20px}}@container (width<=400px){.refined-platform .fusion-design-labels text[font-size="17"]{font-size:24px}}@container (width<=330px){.refined-platform .fusion-design-labels text[font-size="17"]{font-size:28px}}@media (max-width:900px){.refined-platform .foundation-comparison{gap:18px 2px}.refined-platform .foundation-panel:nth-child(odd) .foundation-panel-label{padding-left:0}}@media (max-width:850px){.refined-platform .chapter-heading{margin-bottom:32px;display:block}.refined-platform .chapter-heading>p:last-child{margin-top:22px;padding-left:0}.refined-platform .fusion-design{grid-template-columns:minmax(0,1fr);gap:30px}.refined-platform .fusion-design-figure{flex-direction:column;width:100%;max-width:480px;margin-inline:auto;display:flex}.refined-platform .fusion-design-illustration{max-width:none;margin:16px 0 0}.refined-platform .fusion-design-note{order:2;margin-top:8px}.refined-platform .foundation-principles{grid-template-columns:repeat(2,minmax(0,1fr));gap:28px;padding:0}.refined-platform .foundation-study-instrument,.refined-platform .foundation-mouse-study{grid-template-columns:minmax(0,1fr);gap:20px}.refined-platform .foundation-image-finding,.refined-platform .foundation-mouse-study>p,.refined-platform .foundation-image-source{padding-left:0}.refined-platform .refined-figure-utilities{grid-template-columns:minmax(0,.7fr) minmax(0,1.3fr);column-gap:28px}}@media (max-width:600px){.refined-platform .chapter-heading{margin-bottom:28px}.refined-platform .chapter-heading>p:last-child{margin-top:20px}.refined-platform .fusion-design-figure{max-width:400px}.refined-platform .fusion-design-caption>span{font-size:18px}.refined-platform .fusion-design-caption p{font-size:13px}.refined-platform .foundation-principles{grid-template-columns:minmax(0,1fr);gap:24px}.refined-platform .foundation-principles article{padding-left:18px}.refined-platform .foundation-study{margin-top:36px;padding-top:24px}.refined-platform .foundation-study-heading .refined-foundation-eyebrow{margin-bottom:8px}.refined-platform .foundation-panel-label{min-height:32px;padding-bottom:9px;font-size:14px}.refined-platform .refined-figure-utilities{grid-template-columns:minmax(0,1fr);gap:0}.refined-platform .foundation-image-source{column-gap:20px}.refined-platform .foundation-image-source>span{margin-top:3px}}.refined-platform{scroll-margin-top:-52px}.proposal-development{scroll-margin-top:-44px}@media (max-width:700px){.refined-platform,.proposal-development{scroll-margin-top:-32px}}.citation-library .research-paper-citation{padding-bottom:26px}.citation-library .paper-citation-links{color:var(--ink);flex-wrap:wrap;align-items:baseline;gap:10px 24px;margin-bottom:24px;font-size:13px;display:flex}.citation-library .paper-citation-links .paper-publication-link{margin-bottom:0}.citation-library .paper-citation-links a{text-underline-offset:3px;text-decoration:underline}.citation-library .paper-details{border-top:1px solid var(--line)}.citation-library .paper-details summary{color:var(--ink);cursor:pointer;padding:14px 0;font-size:14px;font-weight:500;line-height:1.6}.citation-library .paper-details summary::marker{color:var(--ink)}.citation-library .paper-details summary:focus-visible{outline:2px solid var(--ink);outline-offset:4px}.citation-library .paper-annotation>p{font-size:15px;line-height:1.75}.citation-library .paper-annotation .paper-limit{font-size:14px;line-height:1.75}.citation-library .paper-details .paper-annotation{padding-top:6px}.citation-library .paper-details .paper-limit{margin-bottom:4px}@media (max-width:760px){.citation-library .paper-citation-links{gap:10px 20px}.citation-library .paper-details summary{min-height:48px}}:root{--masthead-utility-height:40px;--masthead-navigation-height:64px;--masthead-reading-height:64px}html{scroll-padding-top:calc(var(--masthead-reading-height) + 22px);scrollbar-gutter:stable}.site>header.site-header.masthead{--header-gutter:max(4.5vw, calc((100vw - 1310.4px) / 2));top:calc(-1 * var(--masthead-utility-height));z-index:60;grid-template-columns:176px minmax(0,1fr);grid-template-rows:var(--masthead-utility-height) var(--masthead-navigation-height);width:100%;height:104px;min-height:104px;padding:0 var(--header-gutter);background:#fff;border:0;align-items:stretch;gap:0 48px;margin:0;display:grid;position:sticky;box-shadow:0 1px #1f4e7921}.masthead .brand{transform-origin:50%;grid-area:1/1/3;align-items:center;width:fit-content;transition:transform .22s cubic-bezier(.2,.7,.2,1);display:flex}.site .masthead .brand .logo{width:148px;height:auto;display:block}.masthead[data-condensed=true] .brand{transform:translateY(20px)scale(.78)}@media (min-width:1121px){.site>header.site-header.masthead:is([data-utilities-revealed=true],:has(.header-utilities:focus-within)){top:0}.masthead:is([data-utilities-revealed=true],:has(.header-utilities:focus-within)) .brand{transform:none}:is(html:has(.masthead[data-utilities-revealed=true]),html:has(.header-utilities:focus-within)){--masthead-reading-height:104px}}.masthead .header-utilities{color:var(--ink);grid-area:1/2;justify-content:space-between;align-items:center;padding-left:24px;display:flex}.header-utilities>div{align-items:center;gap:28px;height:100%;display:flex}.masthead .header-utilities a{min-height:32px;color:var(--ink);align-items:center;font-size:13px;font-weight:400;display:inline-flex}.masthead .header-utilities a:hover{text-underline-offset:4px;text-decoration:underline}.masthead .header-utilities .header-listing{letter-spacing:.09em;gap:7px;font-size:10px}.header-listing strong{font-weight:500}.masthead .header-primary{margin-right:calc(-1 * var(--header-gutter));padding-right:var(--header-gutter);background:var(--ink);color:#fff;grid-area:2/2;align-items:stretch;gap:24px;padding-left:24px;display:flex}.site .masthead .desktop-nav{flex:1;gap:0;min-width:0;margin:0;display:block;position:static}.desktop-nav-items{justify-content:space-between;align-items:stretch;gap:24px;height:100%;display:flex;position:static}.masthead .nav-item{align-items:stretch;display:flex;position:static}.site .masthead .desktop-nav .nav-item>a{color:#fff;letter-spacing:-.015em;align-items:center;padding:0;font-size:18px;font-weight:500;line-height:1.2;transition:color .16s;display:flex}.site .masthead .desktop-nav a:after{content:none}.site .masthead .desktop-nav .nav-item>a:is(:hover,[aria-current=page]){color:#fff}.site .masthead .desktop-nav a:focus-visible{outline:2px solid var(--cyan);outline-offset:4px;border-radius:0}.nav-disclosure:focus-visible{outline:2px solid var(--cyan);outline-offset:4px;border-radius:0}.nav-disclosure{width:26px;height:40px;color:inherit;cursor:pointer;background:0 0;border:0;flex:0 0 26px;align-self:center;place-items:center;padding:0;display:grid}.nav-disclosure>span{opacity:.8;border-bottom:1px solid;border-right:1px solid;width:6px;height:6px;transition:transform .18s;transform:rotate(45deg)translateY(-2px)}.nav-disclosure[aria-expanded=true]>span{transform:rotate(225deg)translate(-1px,-1px)}.masthead .nav-marker{background:var(--cyan);pointer-events:none;height:3px;transition:transform .22s cubic-bezier(.2,.7,.2,1),width .22s cubic-bezier(.2,.7,.2,1),opacity .12s;position:absolute;bottom:0;left:0}.masthead .header-actions{flex-shrink:0;align-items:center;gap:0;display:flex}.language-switch{color:#fff;grid-template-columns:44px 44px;align-items:center;height:44px;font-size:13px;line-height:1;display:grid;position:relative}.language-switch:before{content:"";background:var(--cyan);width:22px;height:2px;transition:transform .18s cubic-bezier(.2,.7,.2,1);position:absolute;bottom:7px;left:11px;transform:translate(0)}.language-switch[data-locale=zh]:before{transform:translate(44px)}.language-switch:after{content:"";opacity:.25;pointer-events:none;background:currentColor;width:1px;height:12px;position:absolute;top:16px;left:44px}.language-switch>*{height:44px;color:inherit;border:0;place-items:center;padding:0;font-size:13px;font-weight:400;display:grid;position:relative}.language-switch .language-current{color:inherit;font-weight:600}.language-switch[data-locale=en] .language-current,.language-switch[data-locale=zh] .locale-link{grid-area:1/1}.language-switch[data-locale=zh] .language-current,.language-switch[data-locale=en] .locale-link{grid-area:1/2}.masthead .language-switch .locale-link{min-width:0;color:inherit;border:0;padding:0}.language-switch .locale-link:hover{text-underline-offset:6px;text-decoration:underline}.language-switch .locale-link:focus-visible{outline:2px solid var(--cyan);outline-offset:4px}.masthead .menu-toggle{display:none}.masthead .nav-directory{padding:32px var(--header-gutter) 34px;background:var(--ink);color:#fff;visibility:hidden;clip-path:inset(0 0 100%);opacity:0;border-top:1px solid #ffffff38;grid-template-columns:minmax(220px,1fr) minmax(0,2fr);gap:44px;transition:clip-path .2s cubic-bezier(.2,.7,.2,1),opacity .12s,visibility 0s .2s;display:grid;position:absolute;top:100%;left:0;right:0;box-shadow:0 18px 24px -18px #1f4e7973}.masthead .nav-directory[data-open=true]{visibility:visible;clip-path:inset(0);opacity:1;transition-delay:0s}.nav-directory-intro>p{letter-spacing:-.025em;color:#fff;max-width:8em;margin:0 0 24px;font-size:32px;line-height:1.12}.site .masthead .desktop-nav .nav-directory-intro>a{color:#fff;justify-content:space-between;align-items:center;gap:24px;font-size:13px;font-weight:400;display:inline-flex}.nav-directory-intro>a>span{color:var(--cyan)}.nav-latest-results{margin-bottom:18px}.masthead .nav-results-meta{color:#fff;flex-wrap:wrap;align-items:baseline;gap:8px 22px;margin:0;font-size:12px;line-height:1.4;display:flex}.nav-results-meta time{color:#ffffffbf;font-variant-numeric:tabular-nums}.masthead .nav-results-title{color:#fff;letter-spacing:-.02em;max-width:15em;margin:12px 0 8px;font-size:26px;font-weight:400;line-height:1.2}.masthead .nav-results-period{color:#fffc;margin:0 0 6px;font-size:13px;line-height:1.5}.nav-results-editions{flex-wrap:wrap;gap:4px 26px;display:flex}.site .masthead .desktop-nav .nav-results-editions>a{color:#fff;align-items:center;gap:10px;min-height:44px;font-size:14px;font-weight:500;display:inline-flex}.nav-results-editions>a>span{color:var(--cyan);font-size:11px;font-weight:400}.site .masthead .desktop-nav .nav-results-editions>a:hover{text-underline-offset:5px;text-decoration:underline}.nav-directory-links{grid-template-columns:1fr 1fr;align-content:start;gap:0 32px;display:grid}.site .masthead .desktop-nav .nav-directory-links>a{color:#fff;white-space:normal;border-bottom:1px solid #ffffff38;justify-content:space-between;align-items:center;gap:16px;min-height:68px;padding:16px 0;font-size:17px;font-weight:400;line-height:1.35;transition:color .13s;display:flex}.nav-directory-links>a>span:last-child{color:var(--cyan);opacity:0;transition:transform .16s,opacity .16s;transform:translate(-4px)}.nav-directory-links>a:is(:hover,:focus-visible)>span:last-child{opacity:1;transform:none}.site .masthead .desktop-nav .nav-directory-links>a:hover{color:var(--cyan)}.site .research-nav{top:var(--masthead-reading-height)}.site .career-browse{top:calc(var(--masthead-reading-height) + 24px)}.site .refined-platform,.site .proposal-development{scroll-margin-top:40px}.site .skip{z-index:150}@media (min-width:1121px) and (max-width:1280px){.site>header.site-header.masthead{grid-template-columns:150px minmax(0,1fr);column-gap:24px}.site .masthead .brand .logo{width:132px}.masthead .header-primary{gap:16px;padding-left:18px}.site .masthead .desktop-nav .nav-item>a{font-size:16px}.desktop-nav-items{gap:10px}.nav-disclosure{flex-basis:22px;width:22px}.masthead .nav-directory{gap:28px}}@media (max-width:1120px){:root{--masthead-reading-height:76px}.site>header.site-header.masthead{z-index:102;justify-content:space-between;align-items:center;gap:20px;height:76px;min-height:76px;padding-inline:22px;display:flex;top:0}.masthead .brand,.masthead[data-condensed=true] .brand{transform:none}.site .masthead .brand .logo{width:112px}.masthead .header-utilities,.site .masthead .desktop-nav{display:none}.masthead .header-primary{background:0 0;margin:0;padding:0;display:block}.masthead .header-actions{gap:18px}.masthead .language-switch{color:var(--ink)}.masthead .language-switch:before{background:var(--ink)}.masthead .language-current{color:var(--ink)}.site .masthead .menu-toggle{background:var(--ink);color:#fff;cursor:pointer;border:0;justify-content:center;align-items:center;gap:12px;min-width:88px;height:44px;padding:0 13px;font-size:12px;font-weight:500;display:flex}.menu-toggle-icon{width:18px;height:16px;display:block;position:relative}.menu-toggle-icon i{background:currentColor;width:18px;height:1px;transition:transform .18s,top .18s;display:block;position:absolute;top:5px;left:0}.menu-toggle-icon i:last-child{width:12px;top:11px}.menu-toggle[aria-expanded=true] .menu-toggle-icon i{top:8px;transform:rotate(45deg)}.menu-toggle[aria-expanded=true] .menu-toggle-icon i:last-child{width:18px;transform:rotate(-45deg)}.mobile-menu-shell{z-index:101;inset:var(--menu-top,76px) 0 0;visibility:hidden;pointer-events:none;transition:visibility 0s .18s;display:block;position:fixed}.mobile-menu-shell[data-open=true]{visibility:visible;pointer-events:auto;transition-delay:0s}.mobile-menu-scrim{opacity:0;cursor:default;touch-action:none;background:#1f4e7926;border:0;border-radius:0;width:100%;height:100%;margin:0;padding:0;transition:opacity .18s;position:absolute;inset:0}.mobile-menu-shell[data-open=true] .mobile-menu-scrim{opacity:1}.site .mobile-navigation{z-index:1;overscroll-behavior:contain;background:var(--ink);color:#fff;clip-path:inset(0 0 100%);border:0;max-height:100%;padding:14px 22px 24px;transition:clip-path .2s cubic-bezier(.2,.7,.2,1);display:block;position:relative;overflow-y:auto}.mobile-menu-shell[data-open=true] .mobile-navigation{clip-path:inset(0)}.site .mobile-navigation>a{color:#fff;letter-spacing:-.025em;border-bottom:1px solid #ffffff3b;justify-content:space-between;align-items:center;gap:16px;min-height:66px;padding:15px 0;font-size:27px;line-height:1.2;display:flex}.site .mobile-navigation>a>.mobile-navigation-label{font-size:inherit;color:inherit;font-weight:400}.site .mobile-navigation>a>.mobile-navigation-arrow{color:var(--cyan);opacity:0;font-size:24px}.site .mobile-navigation>a[aria-current=page]{color:var(--cyan);border-bottom-color:#ffffff3b}.site .mobile-navigation>a[aria-current=page]:after{content:none}.site .mobile-navigation>a[aria-current=page]>.mobile-navigation-arrow{opacity:1}.site .mobile-navigation>a:is(:hover,:focus-visible){color:var(--cyan)}.site .mobile-navigation>a:active{background:#ffffff14}.site .mobile-navigation>div{color:#fff;flex-wrap:wrap;gap:8px 36px;margin-top:22px;font-size:15px;display:flex}.site .mobile-navigation>div>a{align-items:center;min-height:44px;display:inline-flex}.site .mobile-navigation a:focus-visible{outline:2px solid var(--cyan);outline-offset:3px}}@media (max-width:374px){.site>header.site-header.masthead{gap:14px;padding-inline:18px}.site .masthead .brand .logo{width:102px}.masthead .header-actions{gap:12px}.site .masthead .menu-toggle{width:44px;min-width:44px;padding:0}.menu-toggle-text{clip-path:inset(50%);white-space:nowrap;width:1px;height:1px;position:absolute;overflow:hidden}.site .mobile-navigation>a{font-size:25px}}@media (prefers-reduced-motion:reduce){.masthead *,.masthead :before,.mobile-menu-shell,.mobile-menu-scrim,.site .mobile-navigation{transition:none!important}}.leadership-profile{color:#333;width:min(1100px,100% - 2*clamp(22px,4.5vw,65px));margin-inline:auto;padding-block:40px 88px}.leadership-return{color:var(--ink);text-underline-offset:5px;align-items:baseline;gap:10px;margin-bottom:36px;padding-block:6px;font-size:14px;display:inline-flex}.leadership-return:hover{text-decoration:underline}.leadership-profile-layout{grid-template-columns:minmax(220px,300px) minmax(0,1fr);align-items:start;gap:28px clamp(40px,6vw,84px);display:grid}.leadership-profile-heading{grid-area:1/2;min-width:0}.site .leadership-profile-heading h1{font-family:var(--sans);letter-spacing:-.035em;color:var(--ink);text-wrap:balance;margin:-.12em 0 18px;font-size:clamp(36px,3.4vw,46px);font-weight:500;line-height:1.15}.leadership-profile-heading>p{color:#555;margin:0;font-size:18px;line-height:1.6}.leadership-profile-portrait{grid-area:1/1/span 2}.leadership-profile-portrait figure{margin:0}.leadership-profile-portrait img{width:100%;height:auto;display:block}.leadership-profile-biography{grid-area:2/2;min-width:0;max-width:68ch}.leadership-profile-biography>p{margin:0 0 21px;font-size:17px;line-height:1.75}.leadership-profile:lang(zh) .leadership-profile-biography>p{line-height:1.95}.leadership-profile-sources{border-top:1px solid var(--line);color:#666;margin-top:28px;padding-top:18px;font-size:13px}.leadership-profile-sources summary{width:fit-content;color:var(--ink);cursor:pointer;padding-block:6px;line-height:1.7}.leadership-profile-sources p{margin:14px 0 0;font-size:13px;line-height:1.75}.leadership-profile-sources a{color:var(--ink);text-underline-offset:3px;text-decoration:underline}@media (max-width:1000px){.leadership-profile-layout{grid-template-columns:230px minmax(0,1fr);column-gap:40px}}@media (max-width:740px){.leadership-profile{padding-block:24px 56px}.leadership-return{margin-bottom:26px}.leadership-profile-layout{grid-template-columns:minmax(0,1fr);gap:24px}.leadership-profile-heading,.leadership-profile-portrait,.leadership-profile-biography{grid-area:auto/1}.site .leadership-profile-heading h1{text-wrap:pretty;margin-top:0;margin-bottom:14px;font-size:clamp(30px,7.7vw,36px)}.leadership-profile-heading>p{font-size:16px}.leadership-profile-portrait{width:180px;max-width:60%}.leadership-profile-biography>p{font-size:16px;line-height:1.8}.leadership-profile-sources{margin-top:24px}}